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Find Clinical Drug Pipeline Developments & Deals by Gannex Pharma
ASC41, once daily oral tablet is a thyroid hormone receptor β (THRβ) agonist. It is under phase 2 clinical development for the treatment of biopsy-confirmed non-alcoholic steatohepatitis (NASH).
ASC42 is an in-house developed, novel non-steroidal, selective, potent FXR agonist with best-in-class potential and global intellectual property, which is investigated for the treatment of Primary Biliary Cholangitis.
ASC42 is an in-house developed, novel non-steroidal, selective, potent FXR agonist with best-in-class potential and global intellectual property. Currently, FXR agonist ASC42 is in Phase II clinical trial in China.
ASC43F First-in-class, fixed-dose combination oral tablet with dual targets of thyroid hormone receptor beta and farnesoid X receptor for the treatment of NASH.
ASC42 data indicated there was no pruritus observed during 14-day treatment of the once-daily human therapeutic dose of 15 mg and FXR target engagement biomarker FGF19 increased 1,780% on Day 14 of treatment with 15 mg dose.
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