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Offering","leadProduct":"Gemcitabine","moa":"","url1":"","url2":"","graph1":null,"graph2":null,"graph3":"Theriva Biologics","amount2":0,"therapeuticAreaNew":null,"highestDevelopmentStatusNew":null,"highestDevelopmentShortName":null,"therapeuticAreaShortName":null,"productSubType":"","amount2New":0,"dosageForm":"","sponsorNew":"Theriva Biologics \/ Alliance Global Partners","highestDevelopmentStatusID":null,"companyTruncated":"Theriva Biologics \/ Alliance Global Partners"}]
Find Clinical Drug Pipeline Developments & Deals for Gemcitabine
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Loqtorzi (toripalimab-tpzi) is an anti-PD-1 monoclonal antibody, which is an approved product in combination with cisplatin and gemcitabine for the first-line treatment of adults with metastatic or recurrent locally advanced nasopharyngeal carcinoma.
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The net proceeds will be used to fund the clinical development of the company's lead product VCN-01, which is being evaluated for the treatment of Metastatic Pancreatic Ductal Adenocarcinoma.
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IMM-1-104 is an oral, once-daily deep cyclic inhibitor, small molecule drug. It is being evaluated for pancreatic ductal adenocarcinoma with gemcitabine and nab-paclitaxel.
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Pamrevlumab is a potential first-in-class anti-CTGF fully human monoclonal antibody being developed by FibroGen to inhibit the activity of CTGF, in patients with pancreatic cancer.
Details :
Loqtorzi (toripalimab) is an approved anti-PD-1 monoclonal antibody, in combination with cisplatin and gemcitabine for the first-line treatment of adults with metastatic nasopharyngeal carcinoma.
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SBP-101 (ivospemin) is a small molecule AMD1/ODC1 inhibitor, being evaluated in combination with gemcitabine & nab-paclitaxel for the treatment of metastatic pancreatic ductal adenocarcinoma.
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Cosela (trilaciclib) is being evaluated in combination with chemotherapeutic drugs gemcitabine and carboplatin in patients with metastatic metastatic triple negative breast cancer.
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IMM-101, is a broad-spectrum immunomodulatory agent investigated in combination with gemcitabine and pembrolizumab as first-line treatment in patients with metastatic pancreatic cancer.
Details :
Opdivo (nivolumab) is a PD-1 immune checkpoint inhibitor, which is approved in combination with cisplatin and gemcitabine, for the patients with unresectable or metastatic urothelial carcinoma.
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