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Find Clinical Drug Pipeline Developments & Deals by Gemini Therapeutics

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                          Therapeutic Area by Lead Product

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                          Top Deals by Deal Size (USD bn)

                          01

                          Medlab Asia & Asia Health
                          Not Confirmed
                          Medlab Asia & Asia Health
                          Not Confirmed

                          Details : Disc Medicine (bitopertin) is an oral, selective inhibitor of glycine transporter 1. is developing bitopertin as the potentially first disease-modifying therapy to treat erythropoietic porphyrias – a family of rare, genetic disorders caused by dysregul...

                          Brand Name : DISC-1459

                          Molecule Type : Small molecule

                          Upfront Cash : Undisclosed

                          December 29, 2022

                          Lead Product(s) : Bitopertin

                          Therapeutic Area : Genetic Disease

                          Highest Development Status : Phase II

                          Recipient : Disc medicine

                          Deal Size : $175.0 million

                          Deal Type : Merger

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                          02

                          Medlab Asia & Asia Health
                          Not Confirmed
                          Medlab Asia & Asia Health
                          Not Confirmed

                          Details : The team’s ability to overenroll the study highlights the unmet need and the potential for GEM103 to address these suboptimal outcomes in the setting of regular anti-VEGF therapy and its subsequent depletion in CFH levels causing complement dysfunction...

                          Brand Name : GEM103

                          Molecule Type : Large molecule

                          Upfront Cash : Not Applicable

                          May 13, 2021

                          Lead Product(s) : GEM103,Aflibercept

                          Therapeutic Area : Ophthalmology

                          Highest Development Status : Phase II

                          Sponsor : Not Applicable

                          Deal Size : Not Applicable

                          Deal Type : Not Applicable

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                          03

                          Medlab Asia & Asia Health
                          Not Confirmed
                          Medlab Asia & Asia Health
                          Not Confirmed

                          Details : ReGAtta is a dose escalation trial of GEM103, a recombinant human complement factor H (CFH), in dry AMD patients with CFH loss-of-function gene variants.

                          Brand Name : GEM103

                          Molecule Type : Large molecule

                          Upfront Cash : Not Applicable

                          February 10, 2021

                          Lead Product(s) : GEM103

                          Therapeutic Area : Ophthalmology

                          Highest Development Status : Phase II

                          Sponsor : Not Applicable

                          Deal Size : Not Applicable

                          Deal Type : Not Applicable

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                          04

                          Medlab Asia & Asia Health
                          Not Confirmed
                          Medlab Asia & Asia Health
                          Not Confirmed

                          Details : ReGAtta is a dose escalation trial of GEM103, in dry AMD patients with CFH loss-of-function gene variants. GEM103 targets a genetically-defined subset of age-related macular degeneration (AMD) patients with complement dysregulation.

                          Brand Name : GEM103

                          Molecule Type : Large molecule

                          Upfront Cash : Not Applicable

                          February 01, 2021

                          Lead Product(s) : GEM103

                          Therapeutic Area : Ophthalmology

                          Highest Development Status : Phase II

                          Sponsor : Not Applicable

                          Deal Size : Not Applicable

                          Deal Type : Not Applicable

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                          05

                          Medlab Asia & Asia Health
                          Not Confirmed
                          Medlab Asia & Asia Health
                          Not Confirmed

                          Details : Results showed that, in the four ascending single IVT doses tested (50, 100, 250 and 500 µg of GEM103 in a 50µL dose volume), there were no inflammation, anti-drug antibody, or treatment-related adverse events. A single intravitreal injection of GEM103...

                          Brand Name : GEM103

                          Molecule Type : Large molecule

                          Upfront Cash : Not Applicable

                          November 13, 2020

                          Lead Product(s) : Recombinant human complement Factor H

                          Therapeutic Area : Ophthalmology

                          Highest Development Status : Phase II

                          Sponsor : Not Applicable

                          Deal Size : Not Applicable

                          Deal Type : Not Applicable

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                          06

                          Medlab Asia & Asia Health
                          Not Confirmed
                          Medlab Asia & Asia Health
                          Not Confirmed

                          Details : Proceeds from the transaction are expected to provide Gemini with the capital needed to further develop its clinical programs and preclinical portfolio, including GEM103, Further clinical programs in selected wet AMD populations, Future programs to treat...

                          Brand Name : GEM103

                          Molecule Type : Large molecule

                          Upfront Cash : Undisclosed

                          October 15, 2020

                          Lead Product(s) : GEM103

                          Therapeutic Area : Ophthalmology

                          Highest Development Status : Phase I

                          Sponsor : FS Development Corp

                          Deal Size : $216.0 million

                          Deal Type : Merger

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                          07

                          Medlab Asia & Asia Health
                          Not Confirmed
                          Medlab Asia & Asia Health
                          Not Confirmed

                          Details : The company looking forward to topline data from this study and the potential to initiate a Phase 2 study supported by the CLARITY natural history study data.

                          Brand Name : Undisclosed

                          Molecule Type : Large molecule

                          Upfront Cash : Not Applicable

                          January 09, 2020

                          Lead Product(s) : GEM103

                          Therapeutic Area : Ophthalmology

                          Highest Development Status : Phase I

                          Sponsor : Not Applicable

                          Deal Size : Not Applicable

                          Deal Type : Not Applicable

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