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    [{"orgOrder":0,"company":"Royal DSM","sponsor":"Humanetics Corporation","pharmaFlowCategory":"D","therapeuticArea":"Oncology","country":"U.S.A","productType":"Small molecule","year":"2020","type":"Acquisition","leadProduct":"Genistein","moa":"","graph1":"Oncology","graph2":"Phase I\/ Phase II","graph3":"Royal DSM","amount2":0,"highestDevelopmentShortName":"Ph I\/II","therapeuticAreaShortName":"Oncology","amount2New":0,"dosageForm":"Oral Suspension","sponsorNew":"Royal DSM \/ Humanetics Corporation","highestDevelopmentStatusID":"7","companyTruncated":"Royal DSM \/ Humanetics Corporation"},{"orgOrder":0,"company":"Sesderma","sponsor":"Not Applicable","pharmaFlowCategory":"DU","therapeuticArea":"Infections and Infectious Diseases","country":"SPAIN","productType":"Large molecule","year":"2020","type":"Not Applicable","leadProduct":"Genistein","moa":"ACE2","graph1":"Infections and Infectious 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II","graph3":"Humanetics","amount2":0,"highestDevelopmentShortName":"Ph II","therapeuticAreaShortName":"Infectious Diseases","amount2New":0,"dosageForm":"Suspension","sponsorNew":"Humanetics \/ Department of Defense","highestDevelopmentStatusID":"8","companyTruncated":"Humanetics \/ Department of Defense"},{"orgOrder":0,"company":"Humanetics","sponsor":"National Heart, Lung, and Blood Institute","pharmaFlowCategory":"D","therapeuticArea":"Pulmonary\/Respiratory Diseases","country":"","productType":"Small molecule","year":"2023","type":"Funding","leadProduct":"Genistein","moa":"","graph1":"Pulmonary\/Respiratory Diseases","graph2":"Preclinical","graph3":"Humanetics","amount2":0,"highestDevelopmentShortName":"Preclinical","therapeuticAreaShortName":"Respiratory Diseases","amount2New":0,"dosageForm":"Suspension","sponsorNew":"Humanetics \/ National Heart, Lung, and Blood Institute","highestDevelopmentStatusID":"4","companyTruncated":"Humanetics \/ National Heart, Lung, and Blood Institute"},{"orgOrder":0,"company":"Humanetics","sponsor":"U.S. Department of Defense","pharmaFlowCategory":"D","therapeuticArea":"Trauma (Emergency, Injury, Surgery)","country":"","productType":"Small molecule","year":"2024","type":"Funding","leadProduct":"Genistein","moa":"","graph1":"Technology","graph2":"Phase I\/II","graph3":"Humanetics","amount2":0,"highestDevelopmentShortName":"","therapeuticAreaShortName":"Technology","amount2New":0.94999999999999996,"dosageForm":"","sponsorNew":"Humanetics \/ U.S. Department of Defense","highestDevelopmentStatusID":"14","companyTruncated":"Humanetics \/ U.S. Department of Defense"}]

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                            01

                            Humanetics

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                            Lead Product(s) : Genistein

                            Therapeutic Area : Trauma (Emergency, Injury, Surgery)

                            Study Phase : Phase I

                            Sponsor : U.S. Department of Defense

                            Deal Size : $3.0 million

                            Deal Type : Funding

                            DEALS_DEV arrow-down

                            Uniformed Services University Grants Support for Humanetics Radiation Countermeasure

                            Details : The Funding will be used to advance the company's lead product BIO 300 (genistein), which is being evaluated in the early-stage clinical trial studies for the treatment of Acute Radiation Syndrome.

                            Brand Name : BIO 300

                            Molecule Type : Small molecule

                            Upfront Cash : Undisclosed

                            August 08, 2024

                            Lead Product(s) : Genistein

                            Therapeutic Area : Trauma (Emergency, Injury, Surgery)

                            Highest Development Status : Phase I

                            Sponsor : U.S. Department of Defense

                            Deal Size : $3.0 million

                            Deal Type : Funding

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                            02

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                            Lead Product(s) : Genistein

                            Therapeutic Area : Pulmonary/Respiratory Diseases

                            Study Phase : Preclinical

                            Sponsor : National Heart, Lung, and Blood Institute

                            Deal Size : Undisclosed

                            Deal Type : Funding

                            DEALS_DEV arrow-down

                            Humanetics Corporation Receives Funding to Study New Drug for Idiopathic Pulmonary Fibrosis

                            Details : The funding will support a series of studies with its new drug candidate, BIO 300 (genistein), a unique, highly selective modulator of inflammation, cell cycle arrest and DNA damage repair, as a treatment for idiopathic pulmonary fibrosis.

                            Brand Name : BIO 300

                            Molecule Type : Small molecule

                            Upfront Cash : Undisclosed

                            October 24, 2023

                            Lead Product(s) : Genistein

                            Therapeutic Area : Pulmonary/Respiratory Diseases

                            Highest Development Status : Preclinical

                            Sponsor : National Heart, Lung, and Blood Institute

                            Deal Size : Undisclosed

                            Deal Type : Funding

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                            03

                            Humanetics

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                            Lead Product(s) : Genistein

                            Therapeutic Area : Infections and Infectious Diseases

                            Study Phase : Preclinical

                            Sponsor : Department of Defense

                            Deal Size : Undisclosed

                            Deal Type : Agreement

                            DEALS_DEV arrow-down

                            Humanetics Corporation Awarded Contract from Department of Defense to Develop First FDA Approved Drug to Preve...

                            Details : The agreement aims to develop Humanetics' drug, BIO 300 (genistein), a unique, highly selective modulator of inflammation, cell cycle arrest and DNA damage repair, as a medical countermeasure to prevent bodily harm caused by acute exposure to radiation.

                            Brand Name : BIO 300

                            Molecule Type : Small molecule

                            Upfront Cash : Undisclosed

                            September 06, 2023

                            Lead Product(s) : Genistein

                            Therapeutic Area : Infections and Infectious Diseases

                            Highest Development Status : Preclinical

                            Sponsor : Department of Defense

                            Deal Size : Undisclosed

                            Deal Type : Agreement

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                            04

                            Humanetics

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                            Lead Product(s) : Genistein

                            Therapeutic Area : Infections and Infectious Diseases

                            Study Phase : Phase II

                            Sponsor : Not Applicable

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

                            DEALS_DEV arrow-down

                            Humanetics Corporation Announces Positive Results from Independent Data Monitoring Committee Review of Phase 2...

                            Details : BIO 300 (genistein) is a small molecule drug candidate which increases the killing effect of radiation on multiple tumor thus selectively protect normal tissues and to avoid protection of tumor cells. It is being developed as a treatment of inflammatory ...

                            Brand Name : BIO 300

                            Molecule Type : Small molecule

                            Upfront Cash : Not Applicable

                            February 15, 2023

                            Lead Product(s) : Genistein

                            Therapeutic Area : Infections and Infectious Diseases

                            Highest Development Status : Phase II

                            Sponsor : Not Applicable

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

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                            05

                            Humanetics

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                            Lead Product(s) : Genistein

                            Therapeutic Area : Trauma (Emergency, Injury, Surgery)

                            Study Phase : Phase I

                            Sponsor : Not Applicable

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

                            DEALS_DEV arrow-down

                            Humanetics Corporation Publishes Phase 1 Trial Results for BIO 300 Oral Powder

                            Details : BIO 300 (Genistein) Oral Powder is the Company’s medical countermeasure under development to prevent acute radiation syndrome (ARS). The article details results from the trial including safety, pharmacokinetics, and biomarkers in 34 healthy volunteers.

                            Brand Name : BIO 300

                            Molecule Type : Small molecule

                            Upfront Cash : Not Applicable

                            November 15, 2022

                            Lead Product(s) : Genistein

                            Therapeutic Area : Trauma (Emergency, Injury, Surgery)

                            Highest Development Status : Phase I

                            Sponsor : Not Applicable

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

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                            06

                            Humanetics

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                            Lead Product(s) : Genistein

                            Therapeutic Area : Trauma (Emergency, Injury, Surgery)

                            Study Phase : Phase I

                            Sponsor : Not Applicable

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

                            DEALS_DEV arrow-down

                            Humanetics Corporation Presents at the 68th Annual International Radiation Research Society Meeting

                            Details : BIO 300 Oral Powder (Genistein) is a new formulation that was developed to address unique operational needs of military personnel and first responders. It is a solid oral dosage formulation that is shelf-stable and can be self-administered.

                            Brand Name : BIO 300

                            Molecule Type : Small molecule

                            Upfront Cash : Not Applicable

                            October 25, 2022

                            Lead Product(s) : Genistein

                            Therapeutic Area : Trauma (Emergency, Injury, Surgery)

                            Highest Development Status : Phase I

                            Sponsor : Not Applicable

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

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                            07

                            Humanetics

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                            Lead Product(s) : Genistein

                            Therapeutic Area : Trauma (Emergency, Injury, Surgery)

                            Study Phase : Phase I

                            Sponsor : U.S. Department of Defense

                            Deal Size : $5.1 million

                            Deal Type : Funding

                            DEALS_DEV arrow-down

                            U.S. Department of Defense Awards $5.1 Million to Humanetics Corporation for Continued Development of Radiatio...

                            Details : The new funding will be used to create, manufacture, and test a new formulation of BIO 300 (genistein) that can be self-administered using an auto injector. Auto injectors are commonly used by the military to deliver fast-acting drugs such as atropine an...

                            Brand Name : BIO 300

                            Molecule Type : Small molecule

                            Upfront Cash : Undisclosed

                            June 21, 2022

                            Lead Product(s) : Genistein

                            Therapeutic Area : Trauma (Emergency, Injury, Surgery)

                            Highest Development Status : Phase I

                            Sponsor : U.S. Department of Defense

                            Deal Size : $5.1 million

                            Deal Type : Funding

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                            08

                            Humanetics

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                            Lead Product(s) : Genistein

                            Therapeutic Area : Infections and Infectious Diseases

                            Study Phase : Phase II

                            Sponsor : Not Applicable

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

                            DEALS_DEV arrow-down

                            Humanetics Corporation Expands Long-Haul COVID-19 Trial to Additional Sites

                            Details : BIO 300 (genistein) is an oral drug that patients self-administer daily for 12 weeks following discharge from the hospital. The primary endpoint of the trial is 12 weeks after the start of dosing and patients will be followed for one year.

                            Brand Name : BIO 300

                            Molecule Type : Small molecule

                            Upfront Cash : Not Applicable

                            May 18, 2022

                            Lead Product(s) : Genistein

                            Therapeutic Area : Infections and Infectious Diseases

                            Highest Development Status : Phase II

                            Sponsor : Not Applicable

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

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                            09

                            Humanetics

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                            Lead Product(s) : Genistein

                            Therapeutic Area : Trauma (Emergency, Injury, Surgery)

                            Study Phase : Phase I

                            Sponsor : Not Applicable

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

                            DEALS_DEV arrow-down

                            Humanetics Corporation’s BIO 300 Receives Fast Track Designation from FDA

                            Details : BIO 300 is under advanced development by Humanetics as a medical countermeasure to protect healthy human tissues and organs from harm caused by ionizing radiation. BIO 300 was initially discovered by researchers at the U.S.

                            Brand Name : BIO 300

                            Molecule Type : Small molecule

                            Upfront Cash : Not Applicable

                            August 24, 2021

                            Lead Product(s) : Genistein

                            Therapeutic Area : Trauma (Emergency, Injury, Surgery)

                            Highest Development Status : Phase I

                            Sponsor : Not Applicable

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

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                            Humanetics

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                            Lead Product(s) : Genistein

                            Therapeutic Area : Oncology

                            Study Phase : Preclinical

                            Sponsor : Regenerative Medicine Minnesota

                            Deal Size : Undisclosed

                            Deal Type : Funding

                            DEALS_DEV arrow-down

                            Humanetics Corporation Receives Funding From Regenerative Medicine Minnesota to Study New Drug for Triple Nega...

                            Details : The studies will evaluate the potential of BIO 300 to prevent metastasis of triple negative breast cancer to the lungs following radiotherapy.

                            Brand Name : BIO 300

                            Molecule Type : Small molecule

                            Upfront Cash : Undisclosed

                            June 02, 2021

                            Lead Product(s) : Genistein

                            Therapeutic Area : Oncology

                            Highest Development Status : Preclinical

                            Sponsor : Regenerative Medicine Minnesota

                            Deal Size : Undisclosed

                            Deal Type : Funding

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