Year
DEALS // DEV.
Country
Therapeutic Area
Study Phase
Deal Type
Product Type
Dosage Form
Lead Product
Target
Lead Product(s) : GEN-011,Interleukin 2,Fludarabine Phosphate
Therapeutic Area : Oncology
Study Phase : Phase I
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Genocea Presents Encouraging Initial Data from GEN-011 Phase 1/2a Trial at AACR 2022
Details : GEN-011 is a neoantigen-targeted peripherally derived T cell therapy candidate comprised of autologous CD4+ and CD8+ T cells that are specific for up to 30 ATLAS-identified neoantigens to limit tumor escape.
Brand Name : GEN-011
Molecule Type : Cell and Gene therapy
Upfront Cash : Not Applicable
April 08, 2022
Lead Product(s) : GEN-011,Interleukin 2,Fludarabine Phosphate
Therapeutic Area : Oncology
Highest Development Status : Phase I
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Lead Product(s) : GEN-011,Interleukin 2,Fludarabine Phosphate
Therapeutic Area : Oncology
Study Phase : Phase I
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Genocea to Present Clinical and Preclinical Data at AACR Annual Meeting
Details : GEN-011 is a neoantigen-targeted peripherally derived T cell therapy candidate comprised of autologous CD4+ and CD8+ T cells that are specific for up to 30 ATLAS-identified neoantigens to limit tumor escape.
Brand Name : GEN-011
Molecule Type : Cell and Gene therapy
Upfront Cash : Not Applicable
March 08, 2022
Lead Product(s) : GEN-011,Interleukin 2,Fludarabine Phosphate
Therapeutic Area : Oncology
Highest Development Status : Phase I
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Lead Product(s) : Cancer Vaccine
Therapeutic Area : Oncology
Study Phase : Discovery Platform
Sponsor : Johnson & Johnson Innovative Medicine
Deal Size : Undisclosed
Deal Type : Collaboration
Genocea Biosciences Provides Corporate Update
Details : Under the collaboration, Genocea will use its clinically validated ATLAS™ platform to characterize Janssen-identified antigens as well as assess approaches that could mitigate the impact of Inhibigens
Brand Name : Undisclosed
Molecule Type : Vaccine
Upfront Cash : Undisclosed
January 04, 2022
Lead Product(s) : Cancer Vaccine
Therapeutic Area : Oncology
Highest Development Status : Discovery Platform
Sponsor : Johnson & Johnson Innovative Medicine
Deal Size : Undisclosed
Deal Type : Collaboration
Lead Product(s) : GEN-009,Pembrolizumab
Therapeutic Area : Oncology
Study Phase : Phase I/ Phase II
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Details : GEN-011addresses several critical adoptive T cell therapy challenges . Novel clinical and durable immune response patterns suggest addition of GEN-009 may offer additive clinical benefit in combination with PD-1-based therapies.
Brand Name : GEN-009
Molecule Type : Vaccine
Upfront Cash : Not Applicable
November 09, 2020
Lead Product(s) : GEN-009,Pembrolizumab
Therapeutic Area : Oncology
Highest Development Status : Phase I/ Phase II
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Lead Product(s) : GEN-009,Pembrolizumab
Therapeutic Area : Oncology
Study Phase : Phase I/ Phase II
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Details : The company is advancing two ATLAS-enabled programs: GEN-009, our neoantigen vaccine and GEN-011, our neoantigen-specific cell therapy using T cells derived from peripheral blood.
Brand Name : GEN-009
Molecule Type : Vaccine
Upfront Cash : Not Applicable
November 05, 2020
Lead Product(s) : GEN-009,Pembrolizumab
Therapeutic Area : Oncology
Highest Development Status : Phase I/ Phase II
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Lead Product(s) : GEN-009,Pembrolizumab
Therapeutic Area : Oncology
Study Phase : Phase I/ Phase II
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Genocea Announces Upcoming Data Presentations at Virtual SITC 2020
Details : Presentation will showcase, emerging safety and activity data from GEN-009-101: A phase 1/2a trial of GEN-009, a neoantigen vaccine in combination with PD-1 checkpoint inhibitors (CPI) in advanced solid tumors.
Brand Name : GEN-009
Molecule Type : Vaccine
Upfront Cash : Not Applicable
October 14, 2020
Lead Product(s) : GEN-009,Pembrolizumab
Therapeutic Area : Oncology
Highest Development Status : Phase I/ Phase II
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Lead Product(s) : GEN-011
Therapeutic Area : Oncology
Study Phase : IND Enabling
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Genocea Announces FDA Acceptance of Gen-011 IND Application
Details : The IND allows Genocea to initiate a Phase 1/2a clinical study of GEN-011 in patients who have failed standard-of-care checkpoint inhibitor therapy. The trial will evaluate safety, T cell proliferation and persistence as well as clinical activity.
Brand Name : GEN-011
Molecule Type : Cell and Gene therapy
Upfront Cash : Not Applicable
September 22, 2020
Lead Product(s) : GEN-011
Therapeutic Area : Oncology
Highest Development Status : IND Enabling
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Lead Product(s) : GEN-009,Nivolumab
Therapeutic Area : Oncology
Study Phase : Phase I/ Phase II
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Details : The trial combines GEN-009 with a Standard of Care (SOC) CPI-based regimen approximately four months after the SOC CPI-based regimen is started. Preliminary finding show three patients achieving independent RECIST responses starting from the first GEN-00...
Brand Name : GEN-009
Molecule Type : Vaccine
Upfront Cash : Not Applicable
July 30, 2020
Lead Product(s) : GEN-009,Nivolumab
Therapeutic Area : Oncology
Highest Development Status : Phase I/ Phase II
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Lead Product(s) : GEN-011
Therapeutic Area : Oncology
Study Phase : IND Enabling
Sponsor : Brookline Capital Markets
Deal Size : $80.0 million
Deal Type : Private Placement
Genocea Announces Private Placement Financing of Up to $80 Million
Details : Genocea intends to use the net proceeds from this private placement to fund continued clinical and program development of its neoantigen vaccine GEN-009 and its neoantigen cell therapy GEN-011, as well as for working capital and other general corporate p...
Brand Name : GEN-011
Molecule Type : Cell and Gene therapy
Upfront Cash : Undisclosed
July 22, 2020
Lead Product(s) : GEN-011
Therapeutic Area : Oncology
Highest Development Status : IND Enabling
Sponsor : Brookline Capital Markets
Deal Size : $80.0 million
Deal Type : Private Placement
Lead Product(s) : GEN-009,Nivolumab
Therapeutic Area : Oncology
Study Phase : Phase I/ Phase II
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Genocea Biosceinces Provides Clinical Updates on Its Neoantigen Vaccine
Details : On July 30, 2020, the Company will share initial clinical data on the first 5 patients from Part B of the ongoing Phase 1/2a clinical trial exploring the combination of GEN-009 and immune checkpoint inhibitor-based regimens in advanced solid tumors.
Brand Name : GEN-009
Molecule Type : Vaccine
Upfront Cash : Not Applicable
July 20, 2020
Lead Product(s) : GEN-009,Nivolumab
Therapeutic Area : Oncology
Highest Development Status : Phase I/ Phase II
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
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