Year
DEALS // DEV.
Country
Therapeutic Area
Study Phase
Deal Type
Product Type
Dosage Form
Lead Product
Target
Lead Product(s) : Antibody-drug Conjugate
Therapeutic Area : Oncology
Study Phase : Discovery Platform
Sponsor : Debiopharm
Deal Size : Undisclosed
Deal Type : Licensing Agreement
Debiopharm And Genome & Company Partner On Novel Oncology ADC Family
Details : Debiopharm is granted exclusive global rights to use Genome & Company’s antibodies to develop potential first-in-class ADCs integrating Debiopharm’s Multilink™ technology to treat cancers.
Brand Name : Undisclosed
Molecule Type : Large molecule
Upfront Cash : Undisclosed
June 03, 2024
Lead Product(s) : Antibody-drug Conjugate
Therapeutic Area : Oncology
Highest Development Status : Discovery Platform
Sponsor : Debiopharm
Deal Size : Undisclosed
Deal Type : Licensing Agreement
Lead Product(s) : GEN-001,Avelumab
Therapeutic Area : Oncology
Study Phase : Phase II
Sponsor : Merck & Co
Deal Size : Not Applicable
Deal Type : Not Applicable
Positive Results from Interim Analysis of 'GEN-001' Plus Avelumab (Bavencio®) Phase II Trial
Details : GEN-001 is being developed as an orally administered microbiome therapeutic with Lactococcus lactis, a single strain bacteria isolated from a healthy human. Its anticancer efficacy was proven by activating immune activity of cancer cells.
Brand Name : GEN-001
Molecule Type : Large molecule
Upfront Cash : Not Applicable
May 19, 2023
Lead Product(s) : GEN-001,Avelumab
Therapeutic Area : Oncology
Highest Development Status : Phase II
Sponsor : Merck & Co
Deal Size : Not Applicable
Deal Type : Not Applicable
Lead Product(s) : GEN-001,Pembrolizumab
Therapeutic Area : Oncology
Study Phase : IND Enabling
Sponsor : MSD Pharmaceuticals
Deal Size : Undisclosed
Deal Type : Collaboration
Details : Upon the execution of the agreement, Genome will conduct a phase 2 clinical trial to evaluate the safety and efficacy of its immuno-oncology microbiome therapeutic, GEN-001, in combination with MSD’s anti-PD-1 therapy, KEYTRUDA®, in patients with bili...
Brand Name : GEN-001
Molecule Type : Large molecule
Upfront Cash : Undisclosed
March 03, 2022
Lead Product(s) : GEN-001,Pembrolizumab
Therapeutic Area : Oncology
Highest Development Status : IND Enabling
Sponsor : MSD Pharmaceuticals
Deal Size : Undisclosed
Deal Type : Collaboration
Lead Product(s) : GEN-001,Avelumab
Therapeutic Area : Oncology
Study Phase : Phase I
Recipient : Merck Group
Deal Size : Undisclosed
Deal Type : Collaboration
Details : The collaboration follows in just a year after signing the first agreement with Merck KGaA, Darmstadt, Germany and Pfizer in December 2019 to conduct the first combination clinical trial of avelumab (BAVENCIO®) and GEN-001.
Brand Name : GEN-001
Molecule Type : Large molecule
Upfront Cash : Undisclosed
March 09, 2021
Lead Product(s) : GEN-001,Avelumab
Therapeutic Area : Oncology
Highest Development Status : Phase I
Recipient : Merck Group
Deal Size : Undisclosed
Deal Type : Collaboration
Genome & Company Announces First Patient Dosed in Phase 1/1b Study of GEN-001
Details : The phase 1 study aims to determine the RP2D (recommended Phase 2 dose) of GEN-001 in combination with BAVENCIO® (avelumab).
Brand Name : GEN-001
Molecule Type : Large molecule
Upfront Cash : Not Applicable
October 27, 2020
Lead Product(s) : SB-121
Therapeutic Area : Gastroenterology
Study Phase : Phase I/ Phase II
Recipient : Scioto Biosciences
Deal Size : $26.5 million
Deal Type : Series B Financing
Scioto Biosciences Receives Series B Investment from Genome & Company
Details : Funding will be used to support ongoing clinical development of Scioto’s lead product, SB-121, as a microbiome treatment for diseases affecting the gut-brain axis and gut injury.
Brand Name : SB-121
Molecule Type : Large molecule
Upfront Cash : Undisclosed
August 11, 2020
Lead Product(s) : SB-121
Therapeutic Area : Gastroenterology
Highest Development Status : Phase I/ Phase II
Recipient : Scioto Biosciences
Deal Size : $26.5 million
Deal Type : Series B Financing
Lead Product(s) : GEN-001,Avelumab
Therapeutic Area : Oncology
Study Phase : IND Enabling
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
First Anti-Cancer Microbiome Therapeutic Receives FDA IND Clearance in Asia
Details : Genome & Company which sponsor clinical trial of combination therapy of anti-cancer microbiome and anti-PD1/anti-PD-L1 drug receives FDA IND clearance for GEN-001,
Brand Name : Undisclosed
Molecule Type : Large molecule
Upfront Cash : Not Applicable
April 20, 2020
Lead Product(s) : GEN-001,Avelumab
Therapeutic Area : Oncology
Highest Development Status : IND Enabling
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Lead Product(s) : GEN-001,Avelumab
Therapeutic Area : Oncology
Study Phase : Preclinical
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Details : Clinical partnership of phase 1/1b combination clinical trial with Genome & Company's GEN-001, and avelumab, Merck KGaA, Darmstadt, Germany and Pfizer Inc.'s anti-PD-L1 antibody in cancer.
Brand Name : Undisclosed
Molecule Type : Large molecule
Upfront Cash : Not Applicable
January 13, 2020
Lead Product(s) : GEN-001,Avelumab
Therapeutic Area : Oncology
Highest Development Status : Preclinical
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
LOOKING FOR A SUPPLIER?