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Neoletix","highestDevelopmentStatusID":"4","companyTruncated":"GenScript ProBio \/ Neoletix"},{"orgOrder":0,"company":"GenScript ProBio","sponsor":"Synimmune","pharmaFlowCategory":"D","therapeuticArea":"Oncology","country":"U.S.A","productType":"Large molecule","year":"2021","type":"Collaboration","leadProduct":"Flysyn","moa":"","graph1":"Oncology","graph2":"Phase I\/ Phase II","graph3":"GenScript ProBio","amount2":0,"highestDevelopmentShortName":"Ph I\/II","therapeuticAreaShortName":"Oncology","amount2New":0,"dosageForm":"Intravenous Infusion","sponsorNew":"GenScript ProBio \/ Synimmune","highestDevelopmentStatusID":"7","companyTruncated":"GenScript ProBio \/ Synimmune"},{"orgOrder":0,"company":"GenScript ProBio","sponsor":"AskGene Pharma Inc","pharmaFlowCategory":"D","therapeuticArea":"Oncology","country":"U.S.A","productType":"Large molecule","year":"2021","type":"Licensing Agreement","leadProduct":"Single-domain 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Gene therapy","year":"2024","type":"Not Applicable","leadProduct":"Ciltacabtagene Autoleucel","moa":"","graph1":"Technology","graph2":"Approved","graph3":"GenScript Biotech Corporation","amount2":0,"highestDevelopmentShortName":"Approved","therapeuticAreaShortName":"Technology","amount2New":0.10000000000000001,"dosageForm":"","sponsorNew":"GenScript Biotech Corporation \/ GenScript Biotech Corporation","highestDevelopmentStatusID":"12","companyTruncated":"GenScript Biotech Corporation \/ GenScript Biotech Corporation"}]

Find Clinical Drug Pipeline Developments & Deals by GenScript Biotech Corporation

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                          Therapeutic Area by Lead Product

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                          Top Deals by Deal Size (USD bn)

                          01

                          Antibody Engineering
                          Not Confirmed
                          Antibody Engineering
                          Not Confirmed

                          Details : Carvykti (ciltacabtagene autoleucel) is a FDA approved BCMA-directed genetically modified autologous T cell immunotherapy indicated for the treatment of relapsed/refractory multiple myeloma in adults.

                          Brand Name : Carvykti

                          Molecule Type : Cell and Gene therapy

                          Upfront Cash : Not Applicable

                          August 27, 2024

                          Lead Product(s) : Ciltacabtagene Autoleucel

                          Therapeutic Area : Oncology

                          Highest Development Status : Approved

                          Recipient : Legend Biotech

                          Deal Size : Not Applicable

                          Deal Type : Not Applicable

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                          02

                          Antibody Engineering
                          Not Confirmed
                          Antibody Engineering
                          Not Confirmed

                          Details : Under the partnership, the compamies aims to develop the first circular RNA-based anticancer drug in South Korea using its next-generation mRNA therapy technology.

                          Brand Name : Undisclosed

                          Molecule Type : Large molecule

                          Upfront Cash : Undisclosed

                          November 09, 2023

                          Lead Product(s) : Circular RNA-based Drug

                          Therapeutic Area : Oncology

                          Highest Development Status : Discovery

                          Recipient : NuclixBio

                          Deal Size : Undisclosed

                          Deal Type : Partnership

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                          03

                          Antibody Engineering
                          Not Confirmed
                          Antibody Engineering
                          Not Confirmed

                          Details : EU307 is a fourth-generation CAR-T therapy which targets GPC3-positive solid cancer. It is expected to improve the viability of CAR-T cells and their ability to attack cancer cells through the secretion of cytokine (IL-18).

                          Brand Name : EU307

                          Molecule Type : Cell and Gene therapy

                          Upfront Cash : Not Applicable

                          March 07, 2023

                          Lead Product(s) : EU307

                          Therapeutic Area : Oncology

                          Highest Development Status : Phase I

                          Recipient : Eutilex Inc

                          Deal Size : Not Applicable

                          Deal Type : Not Applicable

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                          04

                          Antibody Engineering
                          Not Confirmed
                          Antibody Engineering
                          Not Confirmed

                          Details : Under the agreement, GenScript ProBio will provide GMP plasmid manufacturing service for RVAC Medicines' program, RVM-V001. The partnership will accelerate its clinical manufacturing of future mRNA-based vaccines targeting infectious diseases such as RSV...

                          Brand Name : RVM-V001

                          Molecule Type : Vaccine

                          Upfront Cash : Undisclosed

                          February 22, 2023

                          Lead Product(s) : RVM-V001

                          Therapeutic Area : Infections and Infectious Diseases

                          Highest Development Status : Phase I

                          Sponsor : RVAC Medicines

                          Deal Size : Undisclosed

                          Deal Type : Partnership

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                          05

                          Antibody Engineering
                          Not Confirmed
                          Antibody Engineering
                          Not Confirmed

                          Details : GenScript ProBio provides IND-enabling CMC service for Bio Immunitas to accelerate the preclinical development of 2 recombinant protein products using Bio Immunitas' proprietary hRPP platform.

                          Brand Name : Undisclosed

                          Molecule Type : Large molecule

                          Upfront Cash : Undisclosed

                          February 08, 2023

                          Lead Product(s) : Undisclosed

                          Therapeutic Area : Technology

                          Highest Development Status : Discovery Platform

                          Recipient : Bio Immunitas

                          Deal Size : Undisclosed

                          Deal Type : Collaboration

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                          06

                          Antibody Engineering
                          Not Confirmed
                          Antibody Engineering
                          Not Confirmed

                          Details : SLC-3010 selectively stimulates anti-tumor immune response and the efficacy of SLC-3010 in eradication of various types of tumor was thoroughly demonstrated through various in vitro and in vivo experiments.

                          Brand Name : SLC-3010

                          Molecule Type : Large molecule

                          Upfront Cash : Not Applicable

                          August 23, 2022

                          Lead Product(s) : SLC-3010

                          Therapeutic Area : Oncology

                          Highest Development Status : IND Enabling

                          Recipient : Selecxine

                          Deal Size : Not Applicable

                          Deal Type : Not Applicable

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                          07

                          Antibody Engineering
                          Not Confirmed
                          Antibody Engineering
                          Not Confirmed

                          Details : Through this agreement, both companies will strategically cooperate in the overall development process, such as discovery, manufacturing, and clinical trials of antibody and cell treatments, and related research and service projects.

                          Brand Name : Undisclosed

                          Molecule Type : Cell and Gene therapy

                          Upfront Cash : Undisclosed

                          July 14, 2022

                          Lead Product(s) : Undisclosed

                          Therapeutic Area : Oncology

                          Highest Development Status : Discovery Platform

                          Sponsor : DAAN Bio Therapeutics

                          Deal Size : Undisclosed

                          Deal Type : Collaboration

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                          08

                          Antibody Engineering
                          Not Confirmed
                          Antibody Engineering
                          Not Confirmed

                          Lead Product(s) : Genetically Modified Mesenchymal Stem Cells Therapy

                          Therapeutic Area : Oncology

                          Study Phase : Undisclosed

                          Recipient : AffyXell

                          Deal Size : Undisclosed

                          Deal Type : Partnership

                          Details : The partnership covers process development and production of viral vectors required for the production of AffyXell’s future cell therapy products. The companies will collaborate in the area of business development, including potential out licensing.

                          Brand Name : Undisclosed

                          Molecule Type : Cell and Gene therapy

                          Upfront Cash : Undisclosed

                          May 16, 2022

                          Lead Product(s) : Genetically Modified Mesenchymal Stem Cells Therapy

                          Therapeutic Area : Oncology

                          Highest Development Status : Undisclosed

                          Recipient : AffyXell

                          Deal Size : Undisclosed

                          Deal Type : Partnership

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                          09

                          Antibody Engineering
                          Not Confirmed
                          Antibody Engineering
                          Not Confirmed

                          Details : The single-domain antibodies involved in this license agreement will be paired with AskGene's proprietary next-generation cytokine therapeutics for cancer immunotherapy and other applications.

                          Brand Name : Undisclosed

                          Molecule Type : Large molecule

                          Upfront Cash : Undisclosed

                          September 26, 2021

                          Lead Product(s) : Single-domain Antibody

                          Therapeutic Area : Oncology

                          Highest Development Status : Discovery

                          Sponsor : AskGene Pharma Inc

                          Deal Size : Undisclosed

                          Deal Type : Licensing Agreement

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                          10

                          Antibody Engineering
                          Not Confirmed
                          Antibody Engineering
                          Not Confirmed

                          Details : GenScript ProBio and SYNIMMUNE GmbH entered into collaboration on FLYSYN, a fms-like tyrosine kinase 3 (FLT3) specific antibody for the treatment of acute myeloid leukemia (AML) project for technology transfer and drug product for Clinical Phase II trial...

                          Brand Name : Flysyn

                          Molecule Type : Large molecule

                          Upfront Cash : Undisclosed

                          September 06, 2021

                          Lead Product(s) : Flysyn

                          Therapeutic Area : Oncology

                          Highest Development Status : Phase I/ Phase II

                          Sponsor : Synimmune

                          Deal Size : Undisclosed

                          Deal Type : Collaboration

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