Year
DEALS // DEV.
Country
Therapeutic Area
Study Phase
Deal Type
Product Type
Dosage Form
Lead Product
Target
Lead Product(s) : Gentamicin Sulfate
Therapeutic Area : Dermatology
Study Phase : Phase I
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Hoth Therapeutics Announces Positive Final Results from 14-day Phase 1b Clinical Trial of BioLexa
Details : BioLexa (gentamicin) is a patented, proprietary antimicrobial topical formulation being developed for treatment of atopic dermatitis. Bacterial biofilms are specialized communities consisting of bacteria adhered to a surface and to other bacteria.
Brand Name : BioLexa
Molecule Type : Small molecule
Upfront Cash : Not Applicable
September 06, 2023
Lead Product(s) : Gentamicin Sulfate
Therapeutic Area : Dermatology
Highest Development Status : Phase I
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Lead Product(s) : Gentamicin Sulfate,Pentetic Acid
Therapeutic Area : Dermatology
Study Phase : Phase I
Sponsor : H.C. Wainwright & Co.
Deal Size : $10.0 million
Deal Type : Private Placement
Details : BioLexa (gentamicin) is a patented, proprietary antimicrobial topical formulation being developed for treatment of diseases mediated by Staphylococcal biofilms. Bacterial biofilms are specialized communities consisting of bacteria adhered to a surface an...
Brand Name : BioLexa
Molecule Type : Small molecule
Upfront Cash : Undisclosed
January 03, 2023
Lead Product(s) : Gentamicin Sulfate,Pentetic Acid
Therapeutic Area : Dermatology
Highest Development Status : Phase I
Sponsor : H.C. Wainwright & Co.
Deal Size : $10.0 million
Deal Type : Private Placement
Lead Product(s) : Gentamicin Sulfate,Pentetic Acid
Therapeutic Area : Dermatology
Study Phase : Phase I
Sponsor : H.C. Wainwright & Co.
Deal Size : $10.0 million
Deal Type : Private Placement
Hoth Therapeutics Announces $10 Million Private Placement Priced At-the-Market Under Nasdaq Rules
Details : BioLexa (gentamicin) is a patented, proprietary antimicrobial topical formulation being developed for treatment of diseases mediated by Staphylococcal biofilms. The BioLexa formulation is optimized to prevent Staphylococcal biofilm formation.
Brand Name : BioLexa
Molecule Type : Small molecule
Upfront Cash : Undisclosed
December 29, 2022
Lead Product(s) : Gentamicin Sulfate,Pentetic Acid
Therapeutic Area : Dermatology
Highest Development Status : Phase I
Sponsor : H.C. Wainwright & Co.
Deal Size : $10.0 million
Deal Type : Private Placement
Lead Product(s) : Gentamicin Sulfate,Pentetic Acid
Therapeutic Area : Dermatology
Study Phase : Phase I
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Details : Receiving clearance for Cohort 2 is the next critical milestone in the Phase 1b clinical trial in Australia. Hoth's atopic dermatitis solution, BioLexa, represents a significant global opportunity and looks forward to advancing the treatment through the ...
Brand Name : BioLexa
Molecule Type : Small molecule
Upfront Cash : Not Applicable
October 12, 2021
Lead Product(s) : Gentamicin Sulfate,Pentetic Acid
Therapeutic Area : Dermatology
Highest Development Status : Phase I
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Lead Product(s) : Gentamicin Sulfate,Pentetic Acid
Therapeutic Area : Dermatology
Study Phase : Phase I
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Details : BioLexa is patented, proprietary antimicrobial topical formulation against diseases mediated by Staphylococcal biofilms. BioLexa formulation is optimized to prevent Staphylococcal biofilm formation, keeping bacteria in more susceptible state to antimicro...
Brand Name : BioLexa
Molecule Type : Small molecule
Upfront Cash : Not Applicable
September 21, 2021
Lead Product(s) : Gentamicin Sulfate,Pentetic Acid
Therapeutic Area : Dermatology
Highest Development Status : Phase I
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Lead Product(s) : Gentamicin Sulfate,Pentetic Acid
Therapeutic Area : Dermatology
Study Phase : Phase I
Sponsor : Novotech
Deal Size : Not Applicable
Deal Type : Not Applicable
Details : The first in human clinical trial is randomized, double-blind, vehicle controlled study to determine the safety, tolerability, PK and efficacy of twice daily application of topical BioLexa™ lotion, in adult and adolescent patients with mild to moderate...
Brand Name : BioLexa
Molecule Type : Small molecule
Upfront Cash : Not Applicable
April 22, 2021
Lead Product(s) : Gentamicin Sulfate,Pentetic Acid
Therapeutic Area : Dermatology
Highest Development Status : Phase I
Sponsor : Novotech
Deal Size : Not Applicable
Deal Type : Not Applicable
Lead Product(s) : Gentamicin Sulfate,Pentetic Acid
Therapeutic Area : Dermatology
Study Phase : Phase I
Sponsor : H.C. Wainwright & Co.
Deal Size : $15.0 million
Deal Type : Private Placement
Hoth Therapeutics Announces $15 Million Private Placement Priced At-the-Market Under Nasdaq Rules
Details : The Company currently intends to use the net proceeds from the private placement for further development of Hoth's product candidates including lead drug BioLexa and for working capital and general corporate purposes.
Brand Name : BioLexa
Molecule Type : Small molecule
Upfront Cash : Undisclosed
March 08, 2021
Lead Product(s) : Gentamicin Sulfate,Pentetic Acid
Therapeutic Area : Dermatology
Highest Development Status : Phase I
Sponsor : H.C. Wainwright & Co.
Deal Size : $15.0 million
Deal Type : Private Placement
Lead Product(s) : Gentamicin Sulfate,Pentetic Acid
Therapeutic Area : Dermatology
Study Phase : Phase I
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Details : Hoth Therapeutics has completed recruitment of Cohort 1 for its upcoming first in human clinical trial of the proprietary BioLexa platform to treat atopic dermatitis, also known as eczema.
Brand Name : BioLexa
Molecule Type : Small molecule
Upfront Cash : Not Applicable
March 01, 2021
Lead Product(s) : Gentamicin Sulfate,Pentetic Acid
Therapeutic Area : Dermatology
Highest Development Status : Phase I
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Lead Product(s) : Gentamicin Sulfate,Pentetic Acid
Therapeutic Area : Dermatology
Study Phase : Phase I
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Details : Following the successful completion of the Phase 1b trial, the Company intends to conduct a Phase 2 trial with adult and adolescent patients to continue clinical investigation of the efficacy of BioLexa Lotion for treatment of mild to moderate atopic der...
Brand Name : BioLexa
Molecule Type : Small molecule
Upfront Cash : Not Applicable
December 10, 2020
Lead Product(s) : Gentamicin Sulfate,Pentetic Acid
Therapeutic Area : Dermatology
Highest Development Status : Phase I
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
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