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    [{"orgOrder":0,"company":"Geron","sponsor":"Not Applicable","pharmaFlowCategory":"DU","therapeuticArea":"Oncology","country":"","productType":"Large molecule","year":"2020","type":"Not Applicable","leadProduct":"Imetelstat","moa":"","graph1":"Oncology","graph2":"Phase III","graph3":"Geron","amount2":0,"highestDevelopmentShortName":"Ph III","therapeuticAreaShortName":"Oncology","amount2New":0,"dosageForm":"Intravenous Infusion","sponsorNew":"Geron \/ Not Applicable","highestDevelopmentStatusID":"10","companyTruncated":"Geron \/ Not Applicable"},{"orgOrder":0,"company":"Geron","sponsor":"Not Applicable","pharmaFlowCategory":"DU","therapeuticArea":"Oncology","country":"","productType":"Large molecule","year":"2020","type":"Not Applicable","leadProduct":"Imetelstat","moa":"","graph1":"Oncology","graph2":"Phase III","graph3":"Geron","amount2":0,"highestDevelopmentShortName":"Ph III","therapeuticAreaShortName":"Oncology","amount2New":0,"dosageForm":"Intravenous 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Pharma","pharmaFlowCategory":"D","therapeuticArea":"Oncology","country":"","productType":"Large molecule","year":"2024","type":"Financing","leadProduct":"Imetelstat","moa":"","graph1":"Technology","graph2":"Phase I\/II","graph3":"Geron","amount2":0.25,"highestDevelopmentShortName":"","therapeuticAreaShortName":"Technology","amount2New":0.94999999999999996,"dosageForm":"","sponsorNew":"Geron \/ Royalty Pharma","highestDevelopmentStatusID":"14","companyTruncated":"Geron \/ Royalty Pharma"}]

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                            01

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                            Lead Product(s) : Imetelstat

                            Therapeutic Area : Oncology

                            Study Phase : Approved

                            Sponsor : Royalty Pharma

                            Deal Size : $250.0 million

                            Deal Type : Financing

                            DEALS_DEV arrow-down

                            Geron Secures up to $375M Funding from Royalty Pharma & Pharmakon Advisors

                            Details : The proceeds will support the commercial launch of Rytelo (imetelstat), a first-in-class treatment that works by inhibiting telomerase enzymatic activity, in the U.S. and potential launch in the EU.

                            Brand Name : Rytelo

                            Molecule Type : Large molecule

                            Upfront Cash : $250.0 million

                            November 07, 2024

                            Lead Product(s) : Imetelstat

                            Therapeutic Area : Oncology

                            Highest Development Status : Approved

                            Sponsor : Royalty Pharma

                            Deal Size : $250.0 million

                            Deal Type : Financing

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                            Lead Product(s) : Imetelstat

                            Therapeutic Area : Oncology

                            Study Phase : Approved

                            Recipient : Onco360

                            Deal Size : Undisclosed

                            Deal Type : Partnership

                            DEALS_DEV arrow-down

                            Onco360 Chosen as Specialty Pharmacy Partner for Rytelo™ (Imetelstat)

                            Details : Onco360 partner by Geron for the distribution of Rytelo (imetelstat)l, telomerase inhibitor, approved for the treatment of adult patients with low to intermediate-risk myelodysplastic syndromes.

                            Brand Name : Rytelo

                            Molecule Type : Large molecule

                            Upfront Cash : Undisclosed

                            July 12, 2024

                            Lead Product(s) : Imetelstat

                            Therapeutic Area : Oncology

                            Highest Development Status : Approved

                            Recipient : Onco360

                            Deal Size : Undisclosed

                            Deal Type : Partnership

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                            Lead Product(s) : Imetelstat

                            Therapeutic Area : Oncology

                            Study Phase : Approved

                            Sponsor : Not Applicable

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

                            DEALS_DEV arrow-down

                            Geron's RYTELO Approved by FDA for Low-Risk MDS with Transfusion-Dependent Anemia

                            Details : Rytelo (imetelstat) is an investigational, novel telomerase inhibitor, administered via intravenous infusion, being developed for relapsed/refractory myelofibrosis.

                            Brand Name : Rytelo

                            Molecule Type : Large molecule

                            Upfront Cash : Not Applicable

                            June 06, 2024

                            Lead Product(s) : Imetelstat

                            Therapeutic Area : Oncology

                            Highest Development Status : Approved

                            Sponsor : Not Applicable

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

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                            Lead Product(s) : Imetelstat

                            Therapeutic Area : Oncology

                            Study Phase : Phase II/ Phase III

                            Sponsor : TD Cowen

                            Deal Size : $150.0 million

                            Deal Type : Public Offering

                            DEALS_DEV arrow-down

                            Geron Corporation Announces Pricing Of $150 Million Underwritten Offering

                            Details : Geron plans to fund commercialization of GRN163L and potential launch of imetelstat for low/intermediate-1 risk myelodysplastic syndromes in the U.S. and EU.

                            Brand Name : GRN163L

                            Molecule Type : Large molecule

                            Upfront Cash : Undisclosed

                            March 19, 2024

                            Lead Product(s) : Imetelstat

                            Therapeutic Area : Oncology

                            Highest Development Status : Phase II/ Phase III

                            Sponsor : TD Cowen

                            Deal Size : $150.0 million

                            Deal Type : Public Offering

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                            05

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                            Lead Product(s) : Imetelstat

                            Therapeutic Area : Oncology

                            Study Phase : Phase III

                            Sponsor : Not Applicable

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

                            DEALS_DEV arrow-down

                            Geron Announces Fifty Percent Enrollment in the Phase 3 IMpactMF Clinical Trial Evaluating Imetelstat in Patie...

                            Details : GRN163L (imetelstat) is an investigational, novel telomerase inhibitor, administered via intravenous infusion, being developed for relapsed/refractory myelofibrosis.

                            Brand Name : GRN163L

                            Molecule Type : Large molecule

                            Upfront Cash : Not Applicable

                            December 06, 2023

                            Lead Product(s) : Imetelstat

                            Therapeutic Area : Oncology

                            Highest Development Status : Phase III

                            Sponsor : Not Applicable

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

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                            Lead Product(s) : Imetelstat

                            Therapeutic Area : Oncology

                            Study Phase : Phase II/ Phase III

                            Sponsor : Not Applicable

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

                            DEALS_DEV arrow-down

                            Geron Announces EMA Validation of Marketing Authorization Application for Imetelstat for the Treatment of Lowe...

                            Details : GRN163L (imetelstat) is an investigational, novel telomerase inhibitor, by which drug inhibits the uncontrolled proliferation of malignant stem and progenitor cells in relapsed/refractory AML or higher risk MDS resulting in malignant cell apoptosis.

                            Brand Name : GRN163L

                            Molecule Type : Large molecule

                            Upfront Cash : Not Applicable

                            September 29, 2023

                            Lead Product(s) : Imetelstat

                            Therapeutic Area : Oncology

                            Highest Development Status : Phase II/ Phase III

                            Sponsor : Not Applicable

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

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                            07

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                            Lead Product(s) : Imetelstat

                            Therapeutic Area : Oncology

                            Study Phase : Phase II/ Phase III

                            Sponsor : Not Applicable

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

                            DEALS_DEV arrow-down

                            Geron Announces PDUFA Date for Imetelstat NDA in Lower Risk MDS

                            Details : GRN163L (imetelstat) is an investigational, novel telomerase inhibitor, by which drug inhibits the uncontrolled proliferation of malignant stem and progenitor cells in Relapsed/Refractory AML or Higher Risk MDS resulting in malignant cell apoptosis.

                            Brand Name : GRN163L

                            Molecule Type : Large molecule

                            Upfront Cash : Not Applicable

                            August 22, 2023

                            Lead Product(s) : Imetelstat

                            Therapeutic Area : Oncology

                            Highest Development Status : Phase II/ Phase III

                            Sponsor : Not Applicable

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

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                            08

                            Geron

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                            Lead Product(s) : Imetelstat

                            Therapeutic Area : Oncology

                            Study Phase : Phase II/ Phase III

                            Sponsor : Not Applicable

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

                            DEALS_DEV arrow-down

                            Geron Announces FDA Acceptance of New Drug Application for Imetelstat for the Treatment of Lower Risk MDS

                            Details : GRN163L (imetelstat) is an investigational, novel telomerase inhibitor, by which drug inhibits the uncontrolled proliferation of malignant stem and progenitor cells in relapsed/refractory AML or higher risk MDS resulting in malignant cell apoptosis.

                            Brand Name : GRN163L

                            Molecule Type : Large molecule

                            Upfront Cash : Not Applicable

                            August 21, 2023

                            Lead Product(s) : Imetelstat

                            Therapeutic Area : Oncology

                            Highest Development Status : Phase II/ Phase III

                            Sponsor : Not Applicable

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

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                            09

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                            Lead Product(s) : Imetelstat

                            Therapeutic Area : Oncology

                            Study Phase : Phase II/ Phase III

                            Sponsor : Not Applicable

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

                            DEALS_DEV arrow-down

                            Geron Announces U.S. Expanded Access Protocol for Imetelstat in Lower Risk MDS

                            Details : GRN163L (imetelstat) is an investigational, novel telomerase inhibitor, by which drug inhibits the uncontrolled proliferation of malignant stem and progenitor cells in Relapsed/Refractory AML or Higher Risk MDS resulting in malignant cell apoptosis.

                            Brand Name : GRN163L

                            Molecule Type : Large molecule

                            Upfront Cash : Not Applicable

                            June 29, 2023

                            Lead Product(s) : Imetelstat

                            Therapeutic Area : Oncology

                            Highest Development Status : Phase II/ Phase III

                            Sponsor : Not Applicable

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

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                            Geron

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                            Lead Product(s) : Imetelstat

                            Therapeutic Area : Oncology

                            Study Phase : Phase III

                            Sponsor : Not Applicable

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

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                            Geron Announces Submission of New Drug Application to FDA for First-in-Class Telomerase Inhibitor Imetelstat

                            Details : GRN163L (imetelstat) is an investigational, telomerase inhibitor, by which drug inhibits the uncontrolled proliferation of malignant stem and investigated for the treatment of transfusion-dependent anemia with low- to intermediate-1 risk myelodysplastic ...

                            Brand Name : GRN163L

                            Molecule Type : Large molecule

                            Upfront Cash : Not Applicable

                            June 20, 2023

                            Lead Product(s) : Imetelstat

                            Therapeutic Area : Oncology

                            Highest Development Status : Phase III

                            Sponsor : Not Applicable

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

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