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Hoffmann-La Roche","pharmaFlowCategory":"D","therapeuticArea":"Oncology","country":"SWITZERLAND","productType":"Antibody-drug Conjugate","year":"2020","type":"Collaboration","leadProduct":"Sacituzumab Govitecan","moa":"||DNA topoisomerase I","graph1":"Oncology","graph2":"Phase I\/ Phase II","graph3":"Immunomedics","amount2":0,"highestDevelopmentShortName":"Ph I\/II","therapeuticAreaShortName":"Oncology","amount2New":0,"dosageForm":"Intravenous Injection","sponsorNew":"Immunomedics \/ Immunomedics","highestDevelopmentStatusID":"7","companyTruncated":"Immunomedics \/ Immunomedics"},{"orgOrder":0,"company":"Gilead Sciences","sponsor":"Inapplicable","pharmaFlowCategory":"DU","therapeuticArea":"Oncology","country":"U.S.A","productType":"Antibody-drug Conjugate","year":"2024","type":"Inapplicable","leadProduct":"Sacituzumab Govitecan","moa":"DNA topoisomerase I","graph1":"Oncology","graph2":"Phase II","graph3":"Gilead Sciences","amount2":0,"highestDevelopmentShortName":"Ph II","therapeuticAreaShortName":"Oncology","amount2New":0,"dosageForm":"Intravenous Injection","sponsorNew":"Gilead Sciences \/ Inapplicable","highestDevelopmentStatusID":"8","companyTruncated":"Gilead Sciences \/ Inapplicable"},{"orgOrder":0,"company":"Immunomedics","sponsor":"Inapplicable","pharmaFlowCategory":"DU","therapeuticArea":"Oncology","country":"U.S.A","productType":"Antibody-drug Conjugate","year":"2020","type":"Inapplicable","leadProduct":"Sacituzumab Govitecan","moa":"DNA topoisomerase I","graph1":"Oncology","graph2":"Phase I","graph3":"Immunomedics","amount2":0,"highestDevelopmentShortName":"Ph I","therapeuticAreaShortName":"Oncology","amount2New":0,"dosageForm":"Intravenous Injection","sponsorNew":"Immunomedics \/ Inapplicable","highestDevelopmentStatusID":"6","companyTruncated":"Immunomedics \/ Inapplicable"},{"orgOrder":0,"company":"Immunomedics","sponsor":"Inapplicable","pharmaFlowCategory":"DU","therapeuticArea":"Oncology","country":"U.S.A","productType":"Antibody-drug Conjugate","year":"2020","type":"Inapplicable","leadProduct":"Sacituzumab Govitecan","moa":"DNA topoisomerase I","graph1":"Oncology","graph2":"Phase I","graph3":"Immunomedics","amount2":0,"highestDevelopmentShortName":"Ph I","therapeuticAreaShortName":"Oncology","amount2New":0,"dosageForm":"Intravenous Injection","sponsorNew":"Immunomedics \/ Inapplicable","highestDevelopmentStatusID":"6","companyTruncated":"Immunomedics \/ Inapplicable"},{"orgOrder":0,"company":"Gilead Sciences","sponsor":"Immunogen","pharmaFlowCategory":"D","therapeuticArea":"Oncology","country":"U.S.A","productType":"Antibody-drug Conjugate","year":"2022","type":"Collaboration","leadProduct":"Pivekimab Sunirine","moa":"||CD123","graph1":"Oncology","graph2":"Phase I\/ Phase II","graph3":"Gilead Sciences","amount2":0,"highestDevelopmentShortName":"Ph I\/II","therapeuticAreaShortName":"Oncology","amount2New":0,"dosageForm":"Intravenous Injection","sponsorNew":"Gilead Sciences \/ Gilead Sciences","highestDevelopmentStatusID":"7","companyTruncated":"Gilead Sciences \/ Gilead Sciences"},{"orgOrder":0,"company":"Gilead Sciences","sponsor":"Tubulis","pharmaFlowCategory":"D","therapeuticArea":"Oncology","country":"GERMANY","productType":"Antibody-drug Conjugate","year":"2024","type":"Licensing Agreement","leadProduct":"Undisclosed","moa":"CIDEB","graph1":"Oncology","graph2":"Discovery Platform","graph3":"Gilead Sciences","amount2":0,"highestDevelopmentShortName":"Discovery Platform","therapeuticAreaShortName":"Oncology","amount2New":0,"dosageForm":"Undisclosed","sponsorNew":"Gilead Sciences \/ Gilead Sciences","highestDevelopmentStatusID":"3","companyTruncated":"Gilead Sciences \/ Gilead Sciences"}]

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                            01

                            Gilead Sciences

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                            The Generic Rx Session
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                            Gilead Sciences

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                            The Generic Rx Session
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                            Lead Product(s) : Seladelpar Lysine,Ursodeoxycholic Acid

                            Therapeutic Area : Hepatology (Liver, Pancreatic, Gall Bladder)

                            Study Phase : Approved FDF

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

                            DEALS_DEV arrow-down

                            Gilead’s Seladelpar Gets Conditional Approval for Primary Biliary Cholangitis

                            Details : Livdelzi (seladelpar) is a novel selective, first-in-class, PPAR delta agonist, indicated to treat adults with primary biliary cholangitis (PBC).

                            Product Name : Livdelzi

                            Product Type : Other Small Molecule

                            Upfront Cash : Inapplicable

                            February 20, 2025

                            Lead Product(s) : Seladelpar Lysine,Ursodeoxycholic Acid

                            Therapeutic Area : Hepatology (Liver, Pancreatic, Gall Bladder)

                            Highest Development Status : Approved FDF

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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                            02

                            Gilead Sciences

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                            The Generic Rx Session
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                            Gilead Sciences

                            U.S.A arrow
                            The Generic Rx Session
                            Not Confirmed
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                            Lead Product(s) : Lenacapavir

                            Therapeutic Area : Infections and Infectious Diseases

                            Study Phase : Phase III

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

                            DEALS_DEV arrow-down

                            FDA Accepts Gilead’s NDA for Twice-Yearly Lenacapavir in HIV Prevention

                            Details : Sunlenca (lenacapavir) is a HIV-1 capsid inhibitor, small molecule drug candidate, which is being evaluated for the treatment of HIV pre-exposure prophylaxis.

                            Product Name : Sunlenca

                            Product Type : Other Small Molecule

                            Upfront Cash : Inapplicable

                            February 18, 2025

                            Lead Product(s) : Lenacapavir

                            Therapeutic Area : Infections and Infectious Diseases

                            Highest Development Status : Phase III

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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                            03

                            Gilead Sciences

                            U.S.A arrow
                            The Generic Rx Session
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                            Gilead Sciences

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                            The Generic Rx Session
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                            Lead Product(s) : Casdatifan

                            Therapeutic Area : Oncology

                            Study Phase : Phase I

                            Recipient : Arcus Biosciences

                            Deal Size : $1,600.0 million

                            Deal Type : Collaboration

                            DEALS_DEV arrow-down

                            Arcus Retains Casdatifan Rights, Prices $150M Common Stock Offering

                            Details : Gilead's window to exercise its option to casdatifan has expired and arcus retains rights to AB521 (casdatifan), a small-molecule inhibitor of HIF-2a.

                            Product Name : AB521

                            Product Type : Other Small Molecule

                            Upfront Cash : $375.0 million

                            February 18, 2025

                            Lead Product(s) : Casdatifan

                            Therapeutic Area : Oncology

                            Highest Development Status : Phase I

                            Recipient : Arcus Biosciences

                            Deal Size : $1,600.0 million

                            Deal Type : Collaboration

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                            04

                            Gilead Sciences

                            U.S.A arrow
                            The Generic Rx Session
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                            Gilead Sciences

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                            The Generic Rx Session
                            Not Confirmed
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                            Lead Product(s) : IDE397,Sacituzumab Govitecan

                            Therapeutic Area : Oncology

                            Study Phase : IND Enabling

                            Recipient : Ideaya Biosciences

                            Deal Size : Undisclosed

                            Deal Type : Collaboration

                            DEALS_DEV arrow-down

                            IDEAYA, Gilead Expand Study on Trodelvy & IDE397 in MTAP-Deletion NSCLC

                            Details : The collaboration aims to evaluate the efficacy and safety of IDE397, potential first-in-class, small molecule MAT2A inhibitor, in combination with Trodelvy to treat MTAP-deletion NSCLC.

                            Product Name : IDE397

                            Product Type : Other Small Molecule

                            Upfront Cash : Undisclosed

                            February 13, 2025

                            Lead Product(s) : IDE397,Sacituzumab Govitecan

                            Therapeutic Area : Oncology

                            Highest Development Status : IND Enabling

                            Recipient : Ideaya Biosciences

                            Deal Size : Undisclosed

                            Deal Type : Collaboration

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                            05

                            Gilead Sciences

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                            The Generic Rx Session
                            Not Confirmed

                            Gilead Sciences

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                            The Generic Rx Session
                            Not Confirmed
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                            Lead Product(s) : Undisclosed

                            Therapeutic Area : Immunology

                            Study Phase : Preclinical

                            Recipient : Leo Pharma

                            Deal Size : $1,700.0 million

                            Deal Type : Partnership

                            DEALS_DEV arrow-down

                            Gilead, LEO Pharma Partner to Develop Programs for Inflammatory Diseases

                            Details : The partnership aims to accelerate the development and commercialization of LEO Pharma’s small molecule oral STAT6 programs for the potential treatment of patients with inflammatory diseases.

                            Product Name : Undisclosed

                            Product Type : Other Small Molecule

                            Upfront Cash : $250.0 million

                            January 11, 2025

                            Lead Product(s) : Undisclosed

                            Therapeutic Area : Immunology

                            Highest Development Status : Preclinical

                            Recipient : Leo Pharma

                            Deal Size : $1,700.0 million

                            Deal Type : Partnership

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                            06

                            Gilead Sciences

                            U.S.A arrow
                            The Generic Rx Session
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                            Gilead Sciences

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                            The Generic Rx Session
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                            Lead Product(s) : ABI-6250

                            Therapeutic Area : Infections and Infectious Diseases

                            Study Phase : IND Enabling

                            Recipient : Assembly Biosciences

                            Deal Size : $30.1 million

                            Deal Type : Collaboration

                            DEALS_DEV arrow-down

                            Assembly Bio Secures $30.1M Funding From Gilead for Clinical Program Development

                            Details : Through the collaboration, Gilead will support the advancement of Assembly Bio’s clinical pipeline, including ABI-6250, which is being evaluated for the treatment of hepatitis.

                            Product Name : Undisclosed

                            Product Type : Small molecule

                            Upfront Cash : Undisclosed

                            December 19, 2024

                            Lead Product(s) : ABI-6250

                            Therapeutic Area : Infections and Infectious Diseases

                            Highest Development Status : IND Enabling

                            Recipient : Assembly Biosciences

                            Deal Size : $30.1 million

                            Deal Type : Collaboration

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                            07

                            Gilead Sciences

                            U.S.A arrow
                            The Generic Rx Session
                            Not Confirmed

                            Gilead Sciences

                            U.S.A arrow
                            The Generic Rx Session
                            Not Confirmed
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                            Lead Product(s) : Undisclosed

                            Therapeutic Area : Technology

                            Study Phase : Discovery Platform

                            Recipient : Terray Therapeutics

                            Deal Size : Undisclosed

                            Deal Type : Collaboration

                            DEALS_DEV arrow-down

                            Gilead and Terray Partner for Multi-Target Discovery Of Small Molecule Therapies

                            Details : The strategic collaboration aims to leverage Terray's tNova platform to discover and develop novel small-molecule therapies targeting multiple targets selected by Gilead.

                            Product Name : Undisclosed

                            Product Type : Small molecule

                            Upfront Cash : Undisclosed

                            December 17, 2024

                            Lead Product(s) : Undisclosed

                            Therapeutic Area : Technology

                            Highest Development Status : Discovery Platform

                            Recipient : Terray Therapeutics

                            Deal Size : Undisclosed

                            Deal Type : Collaboration

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                            08

                            Gilead Sciences

                            U.S.A arrow
                            The Generic Rx Session
                            Not Confirmed

                            Gilead Sciences

                            U.S.A arrow
                            The Generic Rx Session
                            Not Confirmed
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                            Lead Product(s) : Sacituzumab Govitecan

                            Therapeutic Area : Oncology

                            Study Phase : Phase II

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

                            DEALS_DEV arrow-down

                            FDA Grants Breakthrough Designation to Trodelvy® for Small Cell Lung Cancer Treatment

                            Details : Trodelvy (sacituzumab govitecan) is the first approved Trop-2-directed antibody-drug conjugate which is under developemnt for adult patients with extensive-stage small cell lung cancer.

                            Product Name : Trodelvy

                            Product Type : Antibody-drug Conjugate

                            Upfront Cash : Inapplicable

                            December 17, 2024

                            Lead Product(s) : Sacituzumab Govitecan

                            Therapeutic Area : Oncology

                            Highest Development Status : Phase II

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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                            09

                            Gilead Sciences

                            U.S.A arrow
                            The Generic Rx Session
                            Not Confirmed

                            Gilead Sciences

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                            The Generic Rx Session
                            Not Confirmed
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                            Lead Product(s) : Seladelpar Lysine,Ursodeoxycholic Acid

                            Therapeutic Area : Hepatology (Liver, Pancreatic, Gall Bladder)

                            Study Phase : Approved

                            Sponsor : Not Applicable

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

                            DEALS_DEV arrow-down

                            Gilead’s Seladelpar Receives Positive CHMP Opinion for Primary Biliary Cholangitis

                            Details : Livdelzi (seladelpar) is a novel selective, first-in-class, PPAR delta agonist, indicated to treat adults with primary biliary cholangitis (PBC).

                            Product Name : Livdelzi

                            Product Type : Small molecule

                            Upfront Cash : Not Applicable

                            December 13, 2024

                            Lead Product(s) : Seladelpar Lysine,Ursodeoxycholic Acid

                            Therapeutic Area : Hepatology (Liver, Pancreatic, Gall Bladder)

                            Highest Development Status : Approved

                            Sponsor : Not Applicable

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

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                            10

                            Gilead Sciences

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                            The Generic Rx Session
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                            Gilead Sciences

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                            The Generic Rx Session
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                            Lead Product(s) : Undisclosed

                            Therapeutic Area : Oncology

                            Study Phase : Discovery Platform

                            Recipient : Tubulis

                            Deal Size : $435.0 million

                            Deal Type : Licensing Agreement

                            DEALS_DEV arrow-down

                            Gilead Taps German biotech Tubulis for Solid Tumor ADC Development Deal Worth up to $465M

                            Details : The agreement aims to discover and develop an antibody-drug conjugate (ADC) against a solid tumor target using Tubulis’ proprietary Tubutecan and Alco5 platforms.

                            Product Name : Undisclosed

                            Product Type : Antibody-drug Conjugate

                            Upfront Cash : $20.0 million

                            December 03, 2024

                            Lead Product(s) : Undisclosed

                            Therapeutic Area : Oncology

                            Highest Development Status : Discovery Platform

                            Recipient : Tubulis

                            Deal Size : $435.0 million

                            Deal Type : Licensing Agreement

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