Year
DEALS // DEV.
Country
Therapeutic Area
Study Phase
Deal Type
Product Type
Dosage Form
Lead Product
Target
Lead Product(s) : Seralutinib
Therapeutic Area : Pulmonary/Respiratory Diseases
Study Phase : Phase III
Sponsor : Chiesi Group
Deal Size : $326.0 million
Deal Type : Collaboration
Gossamer Bio and Chiesi Group Collaborate to Develop Seralutinib for PAH and PH-ILD
Details : Gossamer Bio continues developing GB002 (seralutinib), an inhaled inhibitor for pulmonary hypertension, while Chiesi will commercialize it outside the U.S.
Brand Name : GB002
Molecule Type : Small molecule
Upfront Cash : Undisclosed
May 06, 2024
Lead Product(s) : Seralutinib
Therapeutic Area : Pulmonary/Respiratory Diseases
Highest Development Status : Phase III
Sponsor : Chiesi Group
Deal Size : $326.0 million
Deal Type : Collaboration
Lead Product(s) : Seralutinib
Therapeutic Area : Cardiology/Vascular Diseases
Study Phase : Phase III
Sponsor : New Enterprise Associates
Deal Size : $212.0 million
Deal Type : Private Placement
Gossamer Bio Announces $212 Million Private Placement Financing
Details : Gossamer intends to use the net proceeds to fund the ongoing development and commercialization of GB002 (seralutinib), a tyrosine kinase inhibitor targeting PDGFRα/β, CSF1R, and c-KIT, for the treatment of pulmonary arterial hypertension (PAH).
Brand Name : GB002
Molecule Type : Small molecule
Upfront Cash : Undisclosed
July 20, 2023
Lead Product(s) : Seralutinib
Therapeutic Area : Cardiology/Vascular Diseases
Highest Development Status : Phase III
Sponsor : New Enterprise Associates
Deal Size : $212.0 million
Deal Type : Private Placement
Lead Product(s) : GB5121
Therapeutic Area : Oncology
Study Phase : Phase I/ Phase II
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Gossamer Halts Work on BTK Inhibitor After 2 Patient Deaths
Details : The FDA has now placed a clinical hold on all trials of GB5121, which was being tested for primary central nervous system lymphoma. Now, all work related to GB5121 has been discontinued and the ongoing studies shelved.
Brand Name : GB5121
Molecule Type : Small molecule
Upfront Cash : Not Applicable
April 03, 2023
Lead Product(s) : GB5121
Therapeutic Area : Oncology
Highest Development Status : Phase I/ Phase II
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Lead Product(s) : Seralutinib
Therapeutic Area : Cardiology/Vascular Diseases
Study Phase : Phase II
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Gossamer Bio Announces Seralutinib Meets Primary Endpoint in Phase 2 TORREY Study in PAH
Details : The efficacy results generated with GB002 (seralutinib) in the context of a favorable safety and tolerability profile highlight compelling potential differentiation for seralutinib as an anti-proliferative, anti-inflammatory, and anti-fibrotic therapeuti...
Brand Name : GB002
Molecule Type : Small molecule
Upfront Cash : Not Applicable
December 06, 2022
Lead Product(s) : Seralutinib
Therapeutic Area : Cardiology/Vascular Diseases
Highest Development Status : Phase II
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Lead Product(s) : Seralutinib
Therapeutic Area : Cardiology/Vascular Diseases
Study Phase : Phase II
Sponsor : EcoR1 Capital
Deal Size : $120.0 million
Deal Type : Private Placement
Gossamer Bio Announces $120 Million Private Placement Financing
Details : Gossamer intends to use the net proceeds from the proposed financing to fund research and development of its other product candidates and development programs and for working capital and general corporate purposes.
Brand Name : GB002
Molecule Type : Small molecule
Upfront Cash : Undisclosed
July 13, 2022
Lead Product(s) : Seralutinib
Therapeutic Area : Cardiology/Vascular Diseases
Highest Development Status : Phase II
Sponsor : EcoR1 Capital
Deal Size : $120.0 million
Deal Type : Private Placement
Lead Product(s) : Seralutinib
Therapeutic Area : Pulmonary/Respiratory Diseases
Study Phase : Phase II
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Details : Seralutinib (GB002) is an inhaled PDGFRα and PDGFRβ inhibitor. The primary objective for this trial is to determine the effect of GB002 on improving pulmonary hemodynamics in subjects with WHO Group 1 PAH who are Functional Class II and III.
Brand Name : GB002
Molecule Type : Small molecule
Upfront Cash : Not Applicable
June 09, 2022
Lead Product(s) : Seralutinib
Therapeutic Area : Pulmonary/Respiratory Diseases
Highest Development Status : Phase II
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Lead Product(s) : GB004
Therapeutic Area : Gastroenterology
Study Phase : Phase II
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Details : Neither statistically significant nor clinically meaningful differences were observed for primary endpoint and secondary endpoints, including histologic and mucosal healing endpoints, for either GB004 treatment group relative to placebo at week 12.
Brand Name : GB004
Molecule Type : Small molecule
Upfront Cash : Not Applicable
April 25, 2022
Lead Product(s) : GB004
Therapeutic Area : Gastroenterology
Highest Development Status : Phase II
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Lead Product(s) : GB1275,Pembrolizumab
Therapeutic Area : Oncology
Study Phase : Phase I/ Phase II
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Details : Presentation includes clinical and biomarker data from the ongoing GB1275 Phase 1/2 clinical trial, KEYNOTE-A36, in advanced solid tumors and corresponding presentations from Johanna Bendell, M.D. and Wells Messersmith, M.D.
Brand Name : GB1275
Molecule Type : Small molecule
Upfront Cash : Not Applicable
November 06, 2020
Lead Product(s) : GB1275,Pembrolizumab
Therapeutic Area : Oncology
Highest Development Status : Phase I/ Phase II
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Lead Product(s) : GB001
Therapeutic Area : Pulmonary/Respiratory Diseases
Study Phase : Phase II
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Despite Phase 2 Failure, Gossamer Bio Sees a Path for Drug in Asthma
Details : The primary endpoint of the trial was not met, though consistent and meaningful numeric reductions in the odds of asthma worsening as compared to placebo were observed across all GB001 groups.
Brand Name : GB001
Molecule Type : Small molecule
Upfront Cash : Not Applicable
October 13, 2020
Lead Product(s) : GB001
Therapeutic Area : Pulmonary/Respiratory Diseases
Highest Development Status : Phase II
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Lead Product(s) : GB004
Therapeutic Area : Gastroenterology
Study Phase : Phase II
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Details : Gossamer Bio will present data relevant to GB004 at United European Gastroenterology Virtual Week 2020, which takes place from October 11th through 13th.
Brand Name : GB004
Molecule Type : Small molecule
Upfront Cash : Not Applicable
October 09, 2020
Lead Product(s) : GB004
Therapeutic Area : Gastroenterology
Highest Development Status : Phase II
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
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