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                          Top Deals by Deal Size (USD bn)

                          01

                          Pharmtech & Ingredients
                          Not Confirmed
                          Pharmtech & Ingredients
                          Not Confirmed

                          Details : OV888 (GV101) is an investigational small molecule capsule, works by inhibiting Rho-associated coiled-coil containing protein kinase 2 receptor for the treatment of cerebral cavernous malformations.

                          Brand Name : OV888

                          Molecule Type : Small molecule

                          Upfront Cash : Not Applicable

                          July 01, 2024

                          Lead Product(s) : GV101

                          Therapeutic Area : Neurology

                          Highest Development Status : Phase I

                          Recipient : Ovid Therapeutics

                          Deal Size : Not Applicable

                          Deal Type : Not Applicable

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                          02

                          Pharmtech & Ingredients
                          Not Confirmed
                          Pharmtech & Ingredients
                          Not Confirmed

                          Details : Through financing, Sanofi gains a right of first negotiation to license compounds like GV101 for various indications, including immunological and metabolic syndrome.

                          Brand Name : GV101

                          Molecule Type : Small molecule

                          Upfront Cash : Undisclosed

                          February 01, 2024

                          Lead Product(s) : GV101

                          Therapeutic Area : Immunology

                          Highest Development Status : Phase I

                          Sponsor : Sanofi

                          Deal Size : Undisclosed

                          Deal Type : Financing

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                          03

                          Pharmtech & Ingredients
                          Not Confirmed
                          Pharmtech & Ingredients
                          Not Confirmed

                          Details : The collaboration will advance clinical development of GV101, which is currently in a Phase 1 trial, along with other selective, small-molecule compounds from a library of ROCK2 inhibitors, that may penetrate the blood-brain barrier.

                          Brand Name : GV101

                          Molecule Type : Small molecule

                          Upfront Cash : $10.0 million

                          May 01, 2023

                          Lead Product(s) : GV101

                          Therapeutic Area : Neurology

                          Highest Development Status : Phase I

                          Sponsor : Ovid Therapeutics

                          Deal Size : $10.0 million

                          Deal Type : Collaboration

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