Year
DEALS // DEV.
Country
Therapeutic Area
Study Phase
Deal Type
Product Type
Dosage Form
Lead Product
Target
Lead Product(s) : GV101
Therapeutic Area : Neurology
Study Phase : Phase I
Recipient : Ovid Therapeutics
Deal Size : Not Applicable
Deal Type : Not Applicable
Ovid and Graviton Announce Data for OV888/GV101 in Cerebral Cavernous Malformations
Details : OV888 (GV101) is an investigational small molecule capsule, works by inhibiting Rho-associated coiled-coil containing protein kinase 2 receptor for the treatment of cerebral cavernous malformations.
Brand Name : OV888
Molecule Type : Small molecule
Upfront Cash : Not Applicable
July 01, 2024
Lead Product(s) : GV101
Therapeutic Area : Neurology
Highest Development Status : Phase I
Recipient : Ovid Therapeutics
Deal Size : Not Applicable
Deal Type : Not Applicable
Lead Product(s) : GV101
Therapeutic Area : Immunology
Study Phase : Phase I
Sponsor : Sanofi
Deal Size : Undisclosed
Deal Type : Financing
Graviton Receives Sanofi Investment to Advance Next-Generation ROCK2 Inhibitors
Details : Through financing, Sanofi gains a right of first negotiation to license compounds like GV101 for various indications, including immunological and metabolic syndrome.
Brand Name : GV101
Molecule Type : Small molecule
Upfront Cash : Undisclosed
February 01, 2024
Lead Product(s) : GV101
Therapeutic Area : Immunology
Highest Development Status : Phase I
Sponsor : Sanofi
Deal Size : Undisclosed
Deal Type : Financing
Lead Product(s) : GV101
Therapeutic Area : Neurology
Study Phase : Phase I
Sponsor : Ovid Therapeutics
Deal Size : $10.0 million
Deal Type : Collaboration
Details : The collaboration will advance clinical development of GV101, which is currently in a Phase 1 trial, along with other selective, small-molecule compounds from a library of ROCK2 inhibitors, that may penetrate the blood-brain barrier.
Brand Name : GV101
Molecule Type : Small molecule
Upfront Cash : $10.0 million
May 01, 2023
Lead Product(s) : GV101
Therapeutic Area : Neurology
Highest Development Status : Phase I
Sponsor : Ovid Therapeutics
Deal Size : $10.0 million
Deal Type : Collaboration
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