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Find Clinical Drug Pipeline Developments & Deals by Gritstone bio
Details :
The proceeds will fund research and development of company's vaccine programs, including Granite, a personalized neoantigen-based vaccine, being evaluated in a Phase 2/3 study in patients with newly diagnosed, metastatic microsatellite-stable colorectal ...
Details :
Granite (GRT-C901/GRT-R902) is patient-specific neoantigen cancer vaccine. It is being evaluated in combination with immune checkpoint blockade in addition to fluoropyrimidine/bevacizumab for the treatment of front-line metastatic microsatellite stable c...
Details :
The net proceeds from the funding will be used by Gritstone for the advancement of Phase 2 study for GRT-R910, a self-amplifying mRNA vaccine candidate.
Details :
The net proceeds will be used to conduct a Phase 2b comparative study evaluating Gritstone’s self-amplifying mRNA (samRNA) vaccine candidate, GRT-R910, containing Spike plus other viral targets to protect against COVID-19.
Details :
Under the agreement, Gritstone will have a multi-year option for a non-exclusive license under Genevant’s LNP technology on a pathogen-by-pathogen basis to develop and commercialize self-amplifying RNA (samRNA) vaccines.
Details :
GRT-R910 is the vaccine is expected to boost and expand first-generation Covid-19 vaccines’ immunogenicity in people aged 60 years and above. GRT-R910 utilises a SAM vector formulated with lipid nanoparticles to deliver antigens against SARS-CoV-2 spik...
Details :
Under the terms of the agreement, NCI will identify patients with metastatic cancer that are eligible for adoptive cell transfer based on the presence of a G12V or G12D KRAS mutation (KRASmut).
Details :
Gritstone’s samRNA vectors enable extended duration and magnitude of antigen expression, in an immunostimulatory context, which together can drive more potent and durable induction of neutralizing antibodies and T cell immunity.
Details :
Gritstone intends to use the net proceeds from the PIPE financing to fund the ongoing clinical development of oncology and infectious disease programs including GRT-C901 and for general corporate purposes.
Details :
New data from CORAL-BOOST study for samRNA Covid-19 Vaccine demonstrate broad and durable immune response; high neutralizing antibody and T cell responses at 6 months post-boost vaccination.
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