Year
DEALS // DEV.
Country
Therapeutic Area
Study Phase
Deal Type
Product Type
Dosage Form
Lead Product
Target
Lead Product(s) : Capsaicin
Therapeutic Area : Neurology
Study Phase : Phase III
Recipient : Averitas Pharma
Deal Size : Not Applicable
Deal Type : Not Applicable
Grünenthal Completes Recruitment for QUTENZA® Post-Surgical Neuropathic Pain Trial
Details : Qutenza (capsaicin) topical patch is approved for neuropathic pain associated with postherpetic neuralgia and diabetic peripheral neuropathy, being investigated for post-surgical neuropathic pain.
Brand Name : CA-008
Molecule Type : Small molecule
Upfront Cash : Not Applicable
November 07, 2024
Lead Product(s) : Capsaicin
Therapeutic Area : Neurology
Highest Development Status : Phase III
Recipient : Averitas Pharma
Deal Size : Not Applicable
Deal Type : Not Applicable
Lead Product(s) : Naloxegol Oxalate
Therapeutic Area : Gastroenterology
Study Phase : Discovery
Recipient : Valinor Pharma
Deal Size : $250.0 million
Deal Type : Acquisition
Grünenthal Continues US Growth Push with $250M Acquisition of Valinor Pharma
Details : Through the acquisition, Grunenthal will leverage the Valinor pipeline, which also includes Movantik (naloxegol), indicated for the treatment of OIC in adult patients with chronic non-cancer pain.
Brand Name : Movantik
Molecule Type : Small molecule
Upfront Cash : Undisclosed
July 22, 2024
Lead Product(s) : Naloxegol Oxalate
Therapeutic Area : Gastroenterology
Highest Development Status : Discovery
Recipient : Valinor Pharma
Deal Size : $250.0 million
Deal Type : Acquisition
Lead Product(s) : Fentanyl
Therapeutic Area : Neurology
Study Phase : Approved
Recipient : Grunenthal Meds
Deal Size : $83.2 million
Deal Type : Collaboration
Grünenthal, Kyowa Kirin International Enter Joint Venture Collaboration
Details : The joint venture collaboration comprises 13 brands across 6 therapeutic areas primarily focused on pain management, including Abstral (fentanyl) and PecFent for breakthrough cancer pain, Moventig for opioid-induced constipation, and Adcal-D3® for osteo...
Brand Name : Abstral
Molecule Type : Small molecule
Upfront Cash : Undisclosed
August 02, 2023
Lead Product(s) : Fentanyl
Therapeutic Area : Neurology
Highest Development Status : Approved
Recipient : Grunenthal Meds
Deal Size : $83.2 million
Deal Type : Collaboration
Lead Product(s) : Undisclosed
Therapeutic Area : Neurology
Study Phase : Preclinical
Recipient : Catalent Pharma Solutions
Deal Size : Undisclosed
Deal Type : Collaboration
Details : The collaboration leads to the successful reformulation of an investigational, orally dosed small molecule in Grünenthal’s pipeline to improve its bioavailability. Phase 1 studies of the molecule will be supported by using the Catalent Xpress Pharmace...
Brand Name : Undisclosed
Molecule Type : Small molecule
Upfront Cash : Undisclosed
March 15, 2023
Lead Product(s) : Undisclosed
Therapeutic Area : Neurology
Highest Development Status : Preclinical
Recipient : Catalent Pharma Solutions
Deal Size : Undisclosed
Deal Type : Collaboration
Lead Product(s) : Fentanyl
Therapeutic Area : Neurology
Study Phase : Approved
Recipient : Kyowa Kirin
Deal Size : Undisclosed
Deal Type : Collaboration
Details : Key products in the portfolio include Abstral® and PecFent® (Fentanyl) for breakthrough cancer pain, Moventig® (Naloxegol) for opioid-induced constipation and Adcal-D3® (calcium and vitamin D3) for osteoporosis.
Brand Name : Abstral
Molecule Type : Small molecule
Upfront Cash : $82.7 million
November 24, 2022
Lead Product(s) : Fentanyl
Therapeutic Area : Neurology
Highest Development Status : Approved
Recipient : Kyowa Kirin
Deal Size : Undisclosed
Deal Type : Collaboration
Lead Product(s) : Testosterone Undecanoate
Therapeutic Area : Endocrinology
Study Phase : Approved
Recipient : Bayer AG
Deal Size : $498.1 million
Deal Type : Acquisition
Grünenthal Closes Deal To Acquire Testosterone Therapy Nebido™ From Bayer For €495 Million
Details : Nebido (having testosterone undecanoate) is the only available injectable long-acting depot preparation of testosterone undecanoate, developed for the treatment of male hypogonadism.
Brand Name : Nebido
Molecule Type : Small molecule
Upfront Cash : Undisclosed
November 02, 2022
Lead Product(s) : Testosterone Undecanoate
Therapeutic Area : Endocrinology
Highest Development Status : Approved
Recipient : Bayer AG
Deal Size : $498.1 million
Deal Type : Acquisition
Lead Product(s) : Resiniferatoxin
Therapeutic Area : Rheumatology
Study Phase : Phase III
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Grünenthal Starts Phase III Trials for Resiniferatoxin in Osteoarthritis-Related Pain
Details : RTX is an intra-articular injection of resiniferatoxin developed for the treatment of pain in patients with moderate to severe pain associated with knee osteoarthritis.
Brand Name : RTX
Molecule Type : Small molecule
Upfront Cash : Not Applicable
August 18, 2022
Lead Product(s) : Resiniferatoxin
Therapeutic Area : Rheumatology
Highest Development Status : Phase III
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Lead Product(s) : Resiniferatoxin
Therapeutic Area : Rheumatology
Study Phase : Phase III
Sponsor : Shionogi
Deal Size : $670.0 million
Deal Type : Licensing Agreement
Details : The agreement includes competitive investment commitments for launch and commercialisation. Manufacturing and supply of RTX (resiniferatoxin) to Shionogi will be carried out exclusively by Grünenthal.
Brand Name : RTX
Molecule Type : Small molecule
Upfront Cash : Undisclosed
August 04, 2022
Lead Product(s) : Resiniferatoxin
Therapeutic Area : Rheumatology
Highest Development Status : Phase III
Sponsor : Shionogi
Deal Size : $670.0 million
Deal Type : Licensing Agreement
Lead Product(s) : Testosterone Undecanoate
Therapeutic Area : Endocrinology
Study Phase : Approved
Recipient : Bayer AG
Deal Size : $506.6 million
Deal Type : Acquisition
Grünenthal Acquires Testosterone Treatment Nebido™ From Bayer
Details : Nebido (testosterone undecanoate) is used for male hypogonadism. It is used for treating clinical symptoms such as regression of secondary sexual characteristics, change in body composition, asthenia, reduced libido or erectile dysfunction due to low tes...
Brand Name : Nebido
Molecule Type : Small molecule
Upfront Cash : Undisclosed
July 14, 2022
Lead Product(s) : Testosterone Undecanoate
Therapeutic Area : Endocrinology
Highest Development Status : Approved
Recipient : Bayer AG
Deal Size : $506.6 million
Deal Type : Acquisition
Lead Product(s) : Rexlemestrocel-L,Hyaluronic Acid
Therapeutic Area : Neurology
Study Phase : Phase III
Recipient : Mesoblast
Deal Size : Not Applicable
Deal Type : Not Applicable
Details : A key objective of MPC-06-ID (rexlemestrocel-L) is to demonstrate reduction in pain and opioid usage and and position rexlemestrocel-L as a potential opioid-sparing agent.
Brand Name : MPC-06-ID
Molecule Type : Cell and Gene therapy
Upfront Cash : Not Applicable
December 15, 2021
Lead Product(s) : Rexlemestrocel-L,Hyaluronic Acid
Therapeutic Area : Neurology
Highest Development Status : Phase III
Recipient : Mesoblast
Deal Size : Not Applicable
Deal Type : Not Applicable
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