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Biosciences","pharmaFlowCategory":"D","therapeuticArea":"Immunology","country":"CHINA","productType":"Cell and Gene therapy","year":"2024","type":"Acquisition","leadProduct":"CMG1A46","moa":"","graph1":"Technology","graph2":"Approved","graph3":"GSK","amount2":0.84999999999999998,"highestDevelopmentShortName":"Approved","therapeuticAreaShortName":"Technology","amount2New":0.10000000000000001,"dosageForm":"","sponsorNew":"GSK \/ GSK","highestDevelopmentStatusID":"12","companyTruncated":"GSK \/ GSK"},{"orgOrder":0,"company":"ViiV Healthcare","sponsor":"Fundaci\u00f3n Hu\u00e9sped","pharmaFlowCategory":"DU","therapeuticArea":"Infections and Infectious Diseases","country":"UNITED KINGDOM","productType":"Small molecule","year":"2024","type":"Not Applicable","leadProduct":"Dolutegravir Sodium","moa":"","graph1":"Technology","graph2":"Approved","graph3":"ViiV Healthcare","amount2":0,"highestDevelopmentShortName":"Approved","therapeuticAreaShortName":"Technology","amount2New":0.10000000000000001,"dosageForm":"","sponsorNew":"ViiV Healthcare \/ Fundaci\u00f3n Hu\u00e9sped","highestDevelopmentStatusID":"12","companyTruncated":"ViiV Healthcare \/ Fundaci\u00f3n Hu\u00e9sped"},{"orgOrder":0,"company":"GSK","sponsor":"Vesalius Therapeutics","pharmaFlowCategory":"D","therapeuticArea":"Neurology","country":"U.S.A","productType":"Small molecule","year":"2024","type":"Agreement","leadProduct":"Undisclosed","moa":"","graph1":"Technology","graph2":"Approved","graph3":"GSK","amount2":0.65000000000000002,"highestDevelopmentShortName":"Approved","therapeuticAreaShortName":"Technology","amount2New":0.10000000000000001,"dosageForm":"","sponsorNew":"GSK \/ GSK","highestDevelopmentStatusID":"12","companyTruncated":"GSK \/ GSK"},{"orgOrder":0,"company":"GSK","sponsor":"Not Applicable","pharmaFlowCategory":"DU","therapeuticArea":"Oncology","country":"","productType":"Large molecule","year":"2024","type":"Not Applicable","leadProduct":"Belantamab Mafodotin","moa":"","graph1":"Technology","graph2":"Approved","graph3":"GSK","amount2":0,"highestDevelopmentShortName":"Approved","therapeuticAreaShortName":"Technology","amount2New":0.10000000000000001,"dosageForm":"","sponsorNew":"GSK \/ Not Applicable","highestDevelopmentStatusID":"12","companyTruncated":"GSK \/ Not Applicable"},{"orgOrder":0,"company":"GSK","sponsor":"Not Applicable","pharmaFlowCategory":"DU","therapeuticArea":"Hepatology (Liver, Pancreatic, Gall Bladder)","country":"","productType":"Small molecule","year":"2024","type":"Not Applicable","leadProduct":"Linerixibat","moa":"","graph1":"Technology","graph2":"Approved","graph3":"GSK","amount2":0,"highestDevelopmentShortName":"Approved","therapeuticAreaShortName":"Technology","amount2New":0.10000000000000001,"dosageForm":"","sponsorNew":"GSK \/ Not Applicable","highestDevelopmentStatusID":"12","companyTruncated":"GSK \/ Not Applicable"}]

    Find Clinical Drug Pipeline Developments & Deals by GSK

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                            01

                            GSK

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                            Lead Product(s) : Linerixibat

                            Therapeutic Area : Hepatology (Liver, Pancreatic, Gall Bladder)

                            Study Phase : Phase III

                            Sponsor : Not Applicable

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

                            DEALS_DEV arrow-down

                            GSK Drug Meets Main Goal in Late-Stage Study to Treat Relentless Itch

                            Details : GSK2330672 (linerixibat) is an IBAT inhibitor, a targeted oral agent with potential to treat cholestatic pruritus associated with primary biliary cholangitis.

                            Brand Name : GSK2330672

                            Molecule Type : Small molecule

                            Upfront Cash : Not Applicable

                            November 19, 2024

                            Lead Product(s) : Linerixibat

                            Therapeutic Area : Hepatology (Liver, Pancreatic, Gall Bladder)

                            Highest Development Status : Phase III

                            Sponsor : Not Applicable

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

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                            02

                            GSK

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                            Lead Product(s) : Belantamab Mafodotin,Bortezomib,Dexamethasone

                            Therapeutic Area : Oncology

                            Study Phase : Phase III

                            Sponsor : Not Applicable

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

                            DEALS_DEV arrow-down

                            GSK's ADC Blenrep Delivers Survival Win Against J&J's Darzalex

                            Details : Blenrep (belantamab mafodotin-blmf) is an anti-BCMA ADC. It is being evaluated in combination with pomalidomide, bortezomib and dexamethasone for the treatment of relapsed/refractory multiple myeloma.

                            Brand Name : Blenrep

                            Molecule Type : Large molecule

                            Upfront Cash : Not Applicable

                            November 14, 2024

                            Lead Product(s) : Belantamab Mafodotin,Bortezomib,Dexamethasone

                            Therapeutic Area : Oncology

                            Highest Development Status : Phase III

                            Sponsor : Not Applicable

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

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                            03

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                            Lead Product(s) : Depemokimab

                            Therapeutic Area : Pulmonary/Respiratory Diseases

                            Study Phase : Phase III

                            Sponsor : Not Applicable

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

                            DEALS_DEV arrow-down

                            GSK Blockbuster Hope Depemokimab Shrinks Polyps in Ph. 3 Trials

                            Details : GSK3511294 (depemokimab) is the first ultra-long-acting biologic with a binding affinity for IL-5. It is being evaluated for the treatment of chronic rhinosinusitis with nasal polyps.

                            Brand Name : GSK3511294

                            Molecule Type : Large molecule

                            Upfront Cash : Not Applicable

                            October 14, 2024

                            Lead Product(s) : Depemokimab

                            Therapeutic Area : Pulmonary/Respiratory Diseases

                            Highest Development Status : Phase III

                            Sponsor : Not Applicable

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

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                            04

                            GSK

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                            Lead Product(s) : Mepolizumab

                            Therapeutic Area : Pulmonary/Respiratory Diseases

                            Study Phase : Approved

                            Sponsor : Not Applicable

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

                            DEALS_DEV arrow-down

                            GSK's Nucala Approved in Japan for Chronic Rhinosinusitis with Nasal Polyps

                            Details : MHLW has approved Nucala (mepolizumab), a monoclonal antibody that targets IL-5, for the treatment of chronic rhinosinusitis with nasal polyps in adult patients.

                            Brand Name : Nucala

                            Molecule Type : Large molecule

                            Upfront Cash : Not Applicable

                            August 29, 2024

                            Lead Product(s) : Mepolizumab

                            Therapeutic Area : Pulmonary/Respiratory Diseases

                            Highest Development Status : Approved

                            Sponsor : Not Applicable

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

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                            05

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                            Lead Product(s) : Undisclosed

                            Therapeutic Area : Pulmonary/Respiratory Diseases

                            Study Phase : Discovery

                            Recipient : Flagship Pioneering

                            Deal Size : $7,200.0 million

                            Deal Type : Collaboration

                            DEALS_DEV arrow-down

                            GSK becomes Flagship's latest partner in $7B biobucks respiratory, immunology pact

                            Details : The Flagship collaborates with GSK to discover and develop a portfolio of future transformational medicines and vaccines for the treatment of respiratory and immunology diseases.

                            Brand Name : Undisclosed

                            Molecule Type : Vaccine

                            Upfront Cash : $150.0 million

                            July 29, 2024

                            Lead Product(s) : Undisclosed

                            Therapeutic Area : Pulmonary/Respiratory Diseases

                            Highest Development Status : Discovery

                            Recipient : Flagship Pioneering

                            Deal Size : $7,200.0 million

                            Deal Type : Collaboration

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                            Lead Product(s) : Ibrexafungerp Citrate

                            Therapeutic Area : Infections and Infectious Diseases

                            Study Phase : Phase II/ Phase III

                            Recipient : Scynexis

                            Deal Size : $593.0 million

                            Deal Type : Licensing Agreement

                            DEALS_DEV arrow-down

                            SCYNEXIS to Receive $10M from GSK for Completed FURI, CARES and NATURE Study Reports

                            Details : Under the agreement, GSK has the rights to develop GSK5458448/SCY-078 (ibrexafungerp), a novel oral glucan synthase inhibitor and commercialize Brexafemme in all countries except the greater China.

                            Brand Name : Brexafemme

                            Molecule Type : Small molecule

                            Upfront Cash : $90.0 million

                            July 23, 2024

                            Lead Product(s) : Ibrexafungerp Citrate

                            Therapeutic Area : Infections and Infectious Diseases

                            Highest Development Status : Phase II/ Phase III

                            Recipient : Scynexis

                            Deal Size : $593.0 million

                            Deal Type : Licensing Agreement

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                            07

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                            Lead Product(s) : Belrestotug,Dostarlimab

                            Therapeutic Area : Oncology

                            Study Phase : Phase II/ Phase III

                            Recipient : Iteos Therapeutics

                            Deal Size : $2,075.0 million

                            Deal Type : Collaboration

                            DEALS_DEV arrow-down

                            iTeos Doses First Patient in GALAXIES Lung-301 Phase 3, Earns $35M from GSK

                            Details : The collaboration aims to advance the clinical development of late-stage product EOS-448 (belrestotug) in combination with Dostarlimab for the treatment of PD-L1 high Non-small Cell Lung Cancer.

                            Brand Name : EOS-448

                            Molecule Type : Large molecule

                            Upfront Cash : $625.0 million

                            July 08, 2024

                            Lead Product(s) : Belrestotug,Dostarlimab

                            Therapeutic Area : Oncology

                            Highest Development Status : Phase II/ Phase III

                            Recipient : Iteos Therapeutics

                            Deal Size : $2,075.0 million

                            Deal Type : Collaboration

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                            08

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                            Lead Product(s) : Nicotine

                            Therapeutic Area : Psychiatry/Psychology

                            Study Phase : Discovery

                            Sponsor : Dr. Reddy\'s Laboratories

                            Deal Size : $632.9 million

                            Deal Type : Acquisition

                            DEALS_DEV arrow-down

                            Dr. Reddy's Acquire Nicotinell and Related Portfolio

                            Details : Through the acquisition, Reddy will leverage the NRT portfolio, which includes Nicotinell (nicotine) in various formats such as lozenges, patches, and gum, across all applicable global market.

                            Brand Name : Nicotinell

                            Molecule Type : Small molecule

                            Upfront Cash : $579.8 million

                            June 26, 2024

                            Lead Product(s) : Nicotine

                            Therapeutic Area : Psychiatry/Psychology

                            Highest Development Status : Discovery

                            Sponsor : Dr. Reddy\'s Laboratories

                            Deal Size : $632.9 million

                            Deal Type : Acquisition

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                            09

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                            Lead Product(s) : Momelotinib

                            Therapeutic Area : Oncology

                            Study Phase : Approved

                            Sponsor : Not Applicable

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

                            DEALS_DEV arrow-down

                            GSK’s Omjjara receives Japanese approval for treatment of myelofibrosis

                            Details : Omjjara (momelotinib) is a once-a-day, oral JAK1/JAK2 and activin A receptor type 1 (ACVR1) inhibitor. It is indicated for the treatment of myelofibrosis.

                            Brand Name : Omjjara

                            Molecule Type : Small molecule

                            Upfront Cash : Not Applicable

                            June 25, 2024

                            Lead Product(s) : Momelotinib

                            Therapeutic Area : Oncology

                            Highest Development Status : Approved

                            Sponsor : Not Applicable

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

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                            GSK

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                            Lead Product(s) : Respiratory Syncytial Virus Vaccine, Adjuvanted

                            Therapeutic Area : Infections and Infectious Diseases

                            Study Phase : Approved

                            Sponsor : Not Applicable

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

                            DEALS_DEV arrow-down

                            FDA Approves Expanded Age Indication for GSK’s Arexvy RSV Vaccine for Adults

                            Details : Arexvy (respiratory syncytial virus vaccine, adjuvanted) is a vaccine drug candidate, which is approved for the treatment of respiratory syncytial virus disease in adults aged 50-59.

                            Brand Name : Arexvy

                            Molecule Type : Vaccine

                            Upfront Cash : Not Applicable

                            June 07, 2024

                            Lead Product(s) : Respiratory Syncytial Virus Vaccine, Adjuvanted

                            Therapeutic Area : Infections and Infectious Diseases

                            Highest Development Status : Approved

                            Sponsor : Not Applicable

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

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