Year
DEALS // DEV.
Country
Therapeutic Area
Study Phase
Deal Type
Product Type
Dosage Form
Lead Product
Target
Lead Product(s) : Hydronidone
Therapeutic Area : Infections and Infectious Diseases
Study Phase : Phase III
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
Gyre Completes Phase 3 Trial Evaluating F351 for CHB Liver Fibrosis
Details : F351 (hydronidone) is an analogue of Pirfenidone, which inhibits p38γ kinase and TGF-β1-induced excessive collagen synthesis HSCs, being developed for chronic hepatitis b associated liver fibrosis.
Product Name : F351
Product Type : Other Small Molecule
Upfront Cash : Inapplicable
October 22, 2024
Lead Product(s) : Hydronidone
Therapeutic Area : Infections and Infectious Diseases
Highest Development Status : Phase III
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
Lead Product(s) : F230
Therapeutic Area : Cardiology/Vascular Diseases
Study Phase : IND Enabling
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
Gyre Pharmaceuticals Gets IND Approval from NMPA for F230 in Pulmonary Hypertension
Details : F230 is an oral, a selective endothelin receptor antagonist, which is being evaluated for the treatment of patients with pulmonary arterial hypertension.
Product Name : F230
Product Type : Other Small Molecule
Upfront Cash : Inapplicable
May 30, 2024
Lead Product(s) : F230
Therapeutic Area : Cardiology/Vascular Diseases
Highest Development Status : IND Enabling
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
Lead Product(s) : Avatrombopag Maleate
Therapeutic Area : Hematology
Study Phase : Approved FDF
Sponsor : Nanjing Healthnice Pharmaceutical Technology
Deal Size : Inapplicable
Deal Type : Inapplicable
Gyre Therapeutics Gets NMPA Approval for Avatrombopag in CLD-Associated Thrombocytopenia
Details : Avatrombopag Maleate, a thrombopoietin receptor agonist is approved by NMPA china. It is given orally for the treatment of thrombocytopenia associated with chronic liver disease.
Product Name : Undisclosed
Product Type : Other Small Molecule
Upfront Cash : Inapplicable
February 07, 2024
Lead Product(s) : Avatrombopag Maleate
Therapeutic Area : Hematology
Highest Development Status : Approved FDF
Sponsor : Nanjing Healthnice Pharmaceutical Technology
Deal Size : Inapplicable
Deal Type : Inapplicable
Lead Product(s) : Hydronidone
Therapeutic Area : Pulmonary/Respiratory Diseases
Study Phase : Phase III
Sponsor : Beijing Continent Pharmaceuticals
Deal Size : Undisclosed
Deal Type : Merger
Details : The combined company will more efficiently conduct clinical research and development of their promising pipeline of product candidates in organ fibrosis and inflammatory diseases, including F351 (hydronidone) for liver fibrosis.
Product Name : F351
Product Type : Other Small Molecule
Upfront Cash : Undisclosed
October 30, 2023
Lead Product(s) : Hydronidone
Therapeutic Area : Pulmonary/Respiratory Diseases
Highest Development Status : Phase III
Sponsor : Beijing Continent Pharmaceuticals
Deal Size : Undisclosed
Deal Type : Merger