Year
DEALS // DEV.
Country
Therapeutic Area
Study Phase
Deal Type
Product Type
Dosage Form
Lead Product
Target
Lead Product(s) : Efgartigimod Alfa,Hyaluronidase
Therapeutic Area : Neurology
Study Phase : Approved FDF
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
Halozyme FDA Approval for VYVGART Self-Injection with ENHANZE Tech
Details : Vyvgart Hytrulo, a subcutaneous combination of efgartigimod alfa, a human IgG1 antibody fragment, and recombinant human hyaluronidase PH20, approved for CIDP and gMG.
Product Name : Vyvgart Hytrulo
Product Type : Antibody
Upfront Cash : Inapplicable
April 10, 2025
Lead Product(s) : Efgartigimod Alfa,Hyaluronidase
Therapeutic Area : Neurology
Highest Development Status : Approved FDF
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
Lead Product(s) : Amivantamab,Lazertinib
Therapeutic Area : Oncology
Study Phase : Approved FDF
Sponsor : Johnson & Johnson Innovative Medicine
Deal Size : Inapplicable
Deal Type : Inapplicable
CHMP Issues Positive Opinion for SC Rybrevant® in Advanced EGFR+ NSCLC
Details : Rybrevant (amivantamab) is a fully-human EGFR-MET bispecific antibody. It is indicated in combination with Lazertinib for EGFR exon 19 deletions or exon 21 L858R substitution mutations NSCLC.
Product Name : Rybrevant
Product Type : Antibody
Upfront Cash : Inapplicable
February 03, 2025
Lead Product(s) : Amivantamab,Lazertinib
Therapeutic Area : Oncology
Highest Development Status : Approved FDF
Sponsor : Johnson & Johnson Innovative Medicine
Deal Size : Inapplicable
Deal Type : Inapplicable
Lead Product(s) : Efgartigimod Alpha,Hyaluronidase
Therapeutic Area : Immunology
Study Phase : Approved FDF
Sponsor : Argenx
Deal Size : $370.0 million
Deal Type : Collaboration
Halozyme Expands Global Collaboration and License Agreement with Argenx for ENHANZE®
Details : Argenx gains access to Halozyme's ENHANZE, a proprietary rHuPH20 enzyme for subcutaneous drug delivery, for six targets, including FcRn target, Vyvgart Hytrulo (efgartigimod alfa and hyaluronidase).
Product Name : Vyvgart Hytrulo
Product Type : Antibody
Upfront Cash : $30.0 million
March 10, 2024
Lead Product(s) : Efgartigimod Alpha,Hyaluronidase
Therapeutic Area : Immunology
Highest Development Status : Approved FDF
Sponsor : Argenx
Deal Size : $370.0 million
Deal Type : Collaboration
Lead Product(s) : Efgartigimod Alpha,Hyaluronidase
Therapeutic Area : Immunology
Study Phase : Approved FDF
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
Details : EC approved VYVGART (efgartigimod alfa and hyaluronidase-qvfc) injection with ENHANZE for subcutaneous (SC) use for the treatment of generalized myasthenia gravis (gMG) in adult patients who are anti-acetylcholine receptor (AChR) antibody positive.
Product Name : Vyvgart Hytrulo
Product Type : Antibody
Upfront Cash : Inapplicable
November 16, 2023
Lead Product(s) : Efgartigimod Alpha,Hyaluronidase
Therapeutic Area : Immunology
Highest Development Status : Approved FDF
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
Lead Product(s) : Efgartigimod Alpha,Hyaluronidase
Therapeutic Area : Immunology
Study Phase : Approved FDF
Sponsor : Argenx
Deal Size : Inapplicable
Deal Type : Inapplicable
Details : VYVGART Hytrulo (efgartigimod alfa and hyaluronidase-qvfc) injection with ENHANZE for subcutaneous (SC) use for the treatment of generalized myasthenia gravis (gMG) in adult patients who are anti-acetylcholine receptor (AChR) antibody positive.
Product Name : Vyvgart Hytrulo
Product Type : Antibody
Upfront Cash : Inapplicable
June 20, 2023
Lead Product(s) : Efgartigimod Alpha,Hyaluronidase
Therapeutic Area : Immunology
Highest Development Status : Approved FDF
Sponsor : Argenx
Deal Size : Inapplicable
Deal Type : Inapplicable
Details : The collaboration will provide Acumen access to Halozyme's ENHANZE® drug delivery technology, based on a recombinant human hyaluronidase PH20 enzyme (rHuPH20), for the development of a subcutaneous formulation of ACU193, the first clinical-stage AβO-ta...
Product Name : ACU193
Product Type : Antibody
Upfront Cash : Undisclosed
June 11, 2023
Lead Product(s) : Hydrocortisone
Therapeutic Area : Endocrinology
Study Phase : Phase I
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
Antares Pharma Announces Positive Results From Phase I Study For ATRS-1902 For Adrenal Crisis Rescue
Details : The results of the Phase I study met its primary objective showing ATRS-1902 delivered a comparable pharmacokinetic profile and also demonstrated that ATRS-1902 was safe and well-tolerated for the treatment of acute adrenal insufficiency.
Product Name : ATRS-1902
Product Type : Steroid
Upfront Cash : Inapplicable
November 01, 2022
Lead Product(s) : Hydrocortisone
Therapeutic Area : Endocrinology
Highest Development Status : Phase I
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
Lead Product(s) : Testosterone Undecanoate
Therapeutic Area : Endocrinology
Study Phase : Approved FDF
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
Details : TLANDO (testosterone undecanoate) is indicated for testosterone replacement therapy in adult males for conditions associated with a deficiency or absence of endogenous testosterone.
Product Name : Tlando
Product Type : Hormone
Upfront Cash : Inapplicable
July 06, 2022
Lead Product(s) : Testosterone Undecanoate
Therapeutic Area : Endocrinology
Highest Development Status : Approved FDF
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
Lead Product(s) : Testosterone Undecanoate
Therapeutic Area : Endocrinology
Study Phase : Approved FDF
Sponsor : Halozyme Therapeutics
Deal Size : $960.0 million
Deal Type : Acquisition
Halozyme Completes Antares Pharma Acquisition
Details : Halozyme and Antares will create a drug delivery and specialty product company. The Antares business consists of a best-in-class, auto injector and ENHANZE platform that offers broad licensing opportunity, with 3 commercial products including Tlando (tes...
Product Name : Tlando
Product Type : Hormone
Upfront Cash : $960.0 million
May 24, 2022
Lead Product(s) : Testosterone Undecanoate
Therapeutic Area : Endocrinology
Highest Development Status : Approved FDF
Sponsor : Halozyme Therapeutics
Deal Size : $960.0 million
Deal Type : Acquisition
Lead Product(s) : Testosterone Undecanoate
Therapeutic Area : Endocrinology
Study Phase : Approved FDF
Sponsor : Halozyme Therapeutics
Deal Size : $960.0 million
Deal Type : Acquisition
Halozyme to Acquire Antares Pharma to Create a Specialty Product and Drug Delivery Leader
Details : The combination of Halozyme and Antares will create a drug delivery and specialty product company. The Antares business consists of a best-in-class, auto injector and ENHANZE platform that offers broad licensing opportunity, with 3 commercial products in...
Product Name : Tlando
Product Type : Hormone
Upfront Cash : $960.0 million
April 13, 2022
Lead Product(s) : Testosterone Undecanoate
Therapeutic Area : Endocrinology
Highest Development Status : Approved FDF
Sponsor : Halozyme Therapeutics
Deal Size : $960.0 million
Deal Type : Acquisition