Year
DEALS // DEV.
Country
Therapeutic Area
Study Phase
Deal Type
Product Type
Dosage Form
Lead Product
Target
Lead Product(s) : HC-7366,Azacitidine,Venetoclax
Therapeutic Area : Oncology
Study Phase : Phase I
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
HiberCell Doses First Patient in Phase 1b Trial of HC-7366 in AML Treatment
Details : HC-7366 is a first-in-human, small molecule activator of the GCN2 kinase, which is being evaluated in combination with venetoclax and azacitidine in AML patients.
Brand Name : HC-7366
Molecule Type : Small molecule
Upfront Cash : Not Applicable
May 28, 2024
Lead Product(s) : HC-7366,Azacitidine,Venetoclax
Therapeutic Area : Oncology
Highest Development Status : Phase I
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Lead Product(s) : HC-7366,Belzutifan
Therapeutic Area : Oncology
Study Phase : Phase I
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
HiberCell Doses First Patient in Merck Collaboration for Advanced ccRCC
Details : HC-7366, a selective activator of general control nonderepressible 2 kinases, is under investigation with Welireg for clear cell renal cell carcinoma treatment.
Brand Name : HC-7366
Molecule Type : Small molecule
Upfront Cash : Not Applicable
May 01, 2024
Lead Product(s) : HC-7366,Belzutifan
Therapeutic Area : Oncology
Highest Development Status : Phase I
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Lead Product(s) : HC-7366,Belzutifan
Therapeutic Area : Oncology
Study Phase : Preclinical
Sponsor : Merck & Co
Deal Size : Undisclosed
Deal Type : Collaboration
Details : The collaboration aims to evaluate HiberCell's HC-7366, a selective activator of the general control nonderepressible 2 kinases in combination with Welireg (belzutifan), Merck’s oral HIF-2α inhibitor for the treatment of clear cell renal cell carcinom...
Brand Name : HC-7366
Molecule Type : Small molecule
Upfront Cash : Undisclosed
December 05, 2023
Lead Product(s) : HC-7366,Belzutifan
Therapeutic Area : Oncology
Highest Development Status : Preclinical
Sponsor : Merck & Co
Deal Size : Undisclosed
Deal Type : Collaboration
HiberCell Maps Forward Path for Novel GCN2 Activator, HC-7366 in Acute Myeloid Leukemia (AML)
Details : HC-7366, a first-in-class, first-in-human GCN2 activator. In preclinical studies, HC-7366 was observed to have robust anti-tumor and immunomodulatory activity in a variety of models of solid tumors and hematological malignancies.
Brand Name : HC-7366
Molecule Type : Large molecule
Upfront Cash : Not Applicable
February 22, 2023
Details : The posters will present the immunomodulatory mechanisms of HC-7366, a differentiated selective, orally bioavailable activator of GCN2 (general controlled nonderepressible 2). HiberCell is currently conducting Phase 1 clinical trials in solid tumors for ...
Brand Name : HC-7366
Molecule Type : Large molecule
Upfront Cash : Not Applicable
November 02, 2022
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