Year
DEALS // DEV.
Country
Therapeutic Area
Study Phase
Deal Type
Product Type
Dosage Form
Lead Product
Target
Lead Product(s) : HDT-521
Therapeutic Area : Oncology
Study Phase : IND Enabling
Sponsor : BARDA
Deal Size : $0.7 million
Deal Type : Partnership
HDT Bio Receives $7.9M EZBAA Contract and Partners with BARDA for NextGen Enabler Program
Details : The partnership aims to support HDT in advancing its next-generation vaccine HDT-521. Which is being evaluated in the preclinical trial studies for the treatment of prostate cancer.
Brand Name : HDT-521
Molecule Type : Vaccine
Upfront Cash : Undisclosed
January 23, 2024
Lead Product(s) : HDT-521
Therapeutic Area : Oncology
Highest Development Status : IND Enabling
Sponsor : BARDA
Deal Size : $0.7 million
Deal Type : Partnership
Lead Product(s) : HDT-301
Therapeutic Area : Infections and Infectious Diseases
Study Phase : Phase I
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
HDT Bio’s COVID-19 Vaccine Wins Regulatory Approval in India
Details : The vaccine uses self-amplifying RNA (or “saRNA”), which replicates itself following administration and is thus effective at extremely low doses. In addition, it is stable at refrigerator temperatures—unlike current mRNA vaccines.
Brand Name : HDT-301
Molecule Type : Vaccine
Upfront Cash : Not Applicable
June 29, 2022
Lead Product(s) : HDT-301
Therapeutic Area : Infections and Infectious Diseases
Highest Development Status : Phase I
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Lead Product(s) : HDT-301
Therapeutic Area : Infections and Infectious Diseases
Study Phase : Phase I
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Details : HDT301, an HDT Bio’s technology uses self-replicating RNA and has the potential to deliver a COVID-19 vaccine targeting multiple variants, providing broad protection from disease and reduced transmission from breakthrough infections.
Brand Name : HDT-301
Molecule Type : Vaccine
Upfront Cash : Not Applicable
April 05, 2022
Lead Product(s) : HDT-301
Therapeutic Area : Infections and Infectious Diseases
Highest Development Status : Phase I
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Lead Product(s) : HGCO19
Therapeutic Area : Infections and Infectious Diseases
Study Phase : Phase I
Sponsor : Quratis Co., Ltd
Deal Size : Not Applicable
Deal Type : Not Applicable
Details : Company RNA-based vaccine, HDT-301 (HGCO19) offers simpler manufacturing, greater stability, and vastly lower effective dosing than current mRNA COVID-19 vaccines.
Brand Name : HDT-301
Molecule Type : Vaccine
Upfront Cash : Not Applicable
December 13, 2021
Lead Product(s) : HGCO19
Therapeutic Area : Infections and Infectious Diseases
Highest Development Status : Phase I
Sponsor : Quratis Co., Ltd
Deal Size : Not Applicable
Deal Type : Not Applicable
Lead Product(s) : HGCO19
Therapeutic Area : Infections and Infectious Diseases
Study Phase : Phase I/ Phase II
Recipient : Gennova Biopharmaceuticals
Deal Size : Not Applicable
Deal Type : Not Applicable
HDT Bio Corp and Gennova Complete Phase 1 Trial of COVID-19 RNA Vaccine in India
Details : Gennova Biopharmaceuticals, successfully completed a Phase 1 trial of its COVID-19 RNA vaccine candidate HGCO19 and Indian regulatory authorities have approved the start of pivotal Phase 2/3 trials.
Brand Name : HGCO19
Molecule Type : Vaccine
Upfront Cash : Not Applicable
August 31, 2021
Lead Product(s) : HGCO19
Therapeutic Area : Infections and Infectious Diseases
Highest Development Status : Phase I/ Phase II
Recipient : Gennova Biopharmaceuticals
Deal Size : Not Applicable
Deal Type : Not Applicable
Lead Product(s) : HDT-301
Therapeutic Area : Infections and Infectious Diseases
Study Phase : Phase II/ Phase III
Sponsor : Quratis Co., Ltd
Deal Size : Undisclosed
Deal Type : Agreement
HDT Bio Announces Agreement With Korea’s Quratis to Co-Develop Innovative COVID-19 Vaccine in Asia
Details : This agreement will enable Quratis to manufacture HDT Bio's next-generation COVID-19 vaccine, HGCO19 and distribute it across much of East Asia.
Brand Name : HGCO19
Molecule Type : Vaccine
Upfront Cash : Undisclosed
August 16, 2021
Lead Product(s) : HDT-301
Therapeutic Area : Infections and Infectious Diseases
Highest Development Status : Phase II/ Phase III
Sponsor : Quratis Co., Ltd
Deal Size : Undisclosed
Deal Type : Agreement
Lead Product(s) : HDT-301
Therapeutic Area : Infections and Infectious Diseases
Study Phase : Phase I/ Phase II
Sponsor : Gennova Biopharmaceuticals
Deal Size : Not Applicable
Deal Type : Not Applicable
HDT Bio Receives Notice to Proceed from FDA for U.S. Phase 1 Clinical Trial of RNA COVID-19 Vaccine
Details : HDT Bio has also developed HGCO19, a LION-based COVID-19 vaccine, in collaboration with Gennova Biopharmaceuticals of Pune, which is currently is being tested in India in a Phase 1/2 clinical trial.
Brand Name : HGCO19
Molecule Type : Vaccine
Upfront Cash : Not Applicable
July 01, 2021
Lead Product(s) : HDT-301
Therapeutic Area : Infections and Infectious Diseases
Highest Development Status : Phase I/ Phase II
Sponsor : Gennova Biopharmaceuticals
Deal Size : Not Applicable
Deal Type : Not Applicable
Lead Product(s) : HDT-301
Therapeutic Area : Infections and Infectious Diseases
Study Phase : Phase I/ Phase II
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Details : HGCO19, is a novel mRNA vaccine candidate containing a short, synthetic version encoding the spike protein (antigen) of the novel coronavirus, SARS-CoV-2, reported to interact with receptors on host cells.
Brand Name : HGCO19
Molecule Type : Vaccine
Upfront Cash : Not Applicable
May 04, 2021
Lead Product(s) : HDT-301
Therapeutic Area : Infections and Infectious Diseases
Highest Development Status : Phase I/ Phase II
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Lead Product(s) : HGCO19
Therapeutic Area : Infections and Infectious Diseases
Study Phase : Preclinical
Recipient : Gennova Biopharmaceuticals
Deal Size : Not Applicable
Deal Type : Not Applicable
Details : The Drugs Controller General of India (DCGI) has granted conditional permission for phases 1 and 2 human clinical trial of the COVID-19 vaccine candidate, HGCO19, developed by the Pune-based Gennova Biopharmaceuticals Ltd in collaboration with HDT, USA.
Brand Name : HGCO19
Molecule Type : Vaccine
Upfront Cash : Not Applicable
December 09, 2020
Lead Product(s) : HGCO19
Therapeutic Area : Infections and Infectious Diseases
Highest Development Status : Preclinical
Recipient : Gennova Biopharmaceuticals
Deal Size : Not Applicable
Deal Type : Not Applicable
Lead Product(s) : HDT-301
Therapeutic Area : Infections and Infectious Diseases
Study Phase : Preclinical
Sponsor : Zoic Capital
Deal Size : $3.0 million
Deal Type : Financing
HDT Bio Announces Completion of Seed Financing Round
Details : Proceeds will be used largely to support continued development of the company’s COVID-19 vaccine candidate, HDT-301. The vaccine is slated to enter clinical trials in Q4 2020 in partnership with the NIH/NIAID.
Brand Name : HDT-301
Molecule Type : Vaccine
Upfront Cash : Undisclosed
October 05, 2020
Lead Product(s) : HDT-301
Therapeutic Area : Infections and Infectious Diseases
Highest Development Status : Preclinical
Sponsor : Zoic Capital
Deal Size : $3.0 million
Deal Type : Financing
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