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Group","sponsor":"Inapplicable","pharmaFlowCategory":"DU","therapeuticArea":"Hematology","country":"GERMANY","productType":"Other Small Molecule","year":"2023","type":"Inapplicable","leadProduct":"Rivaroxaban","moa":"Factor Xa","graph1":"Hematology","graph2":"Approved FDF","graph3":"Tiefenbacher Group","amount2":0,"highestDevelopmentShortName":"","therapeuticAreaShortName":"Hematology","amount2New":0,"dosageForm":"Oral Tablet, Film Coated","sponsorNew":"Tiefenbacher Group \/ Inapplicable","highestDevelopmentStatusID":"15","companyTruncated":"Tiefenbacher Group \/ Inapplicable"},{"orgOrder":0,"company":"Tiefenbacher Group","sponsor":"Inapplicable","pharmaFlowCategory":"DU","therapeuticArea":"Hematology","country":"GERMANY","productType":"Other Small Molecule","year":"2024","type":"Inapplicable","leadProduct":"Rivaroxaban","moa":"Factor Xa","graph1":"Hematology","graph2":"Approved FDF","graph3":"Tiefenbacher 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USA","sponsor":"Inapplicable","pharmaFlowCategory":"DU","therapeuticArea":"Hematology","country":"U.S.A","productType":"Other Small Molecule","year":"2023","type":"Inapplicable","leadProduct":"Enoxaparin Sodium","moa":"Antithrombin III","graph1":"Hematology","graph2":"Approved FDF","graph3":"Techdow USA","amount2":0,"highestDevelopmentShortName":"","therapeuticAreaShortName":"Hematology","amount2New":0,"dosageForm":"Subcutaneous Injection","sponsorNew":"Techdow USA \/ Inapplicable","highestDevelopmentStatusID":"15","companyTruncated":"Techdow USA \/ Inapplicable"},{"orgOrder":0,"company":"Techdow USA","sponsor":"Inapplicable","pharmaFlowCategory":"DU","therapeuticArea":"Hematology","country":"U.S.A","productType":"Other Small Molecule","year":"2023","type":"Inapplicable","leadProduct":"Enoxaparin Sodium","moa":"Antithrombin III","graph1":"Hematology","graph2":"Approved FDF","graph3":"Techdow 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AG","sponsor":"Inapplicable","pharmaFlowCategory":"DU","therapeuticArea":"Hematology","country":"GERMANY","productType":"Other Large Molecule","year":"2024","type":"Inapplicable","leadProduct":"BAY 3018250","moa":"Undisclosed","graph1":"Hematology","graph2":"Phase II","graph3":"Bayer AG","amount2":0,"highestDevelopmentShortName":"Ph II","therapeuticAreaShortName":"Hematology","amount2New":0,"dosageForm":"Undisclosed","sponsorNew":"Bayer AG \/ Inapplicable","highestDevelopmentStatusID":"8","companyTruncated":"Bayer AG \/ Inapplicable"},{"orgOrder":0,"company":"Aspen Pharmacare Holdings","sponsor":"Viatris","pharmaFlowCategory":"D","therapeuticArea":"Hematology","country":"SOUTH AFRICA","productType":"Other Small Molecule","year":"2020","type":"Acquisition","leadProduct":"Fondaparinux Sodium","moa":"Antithrombin III","graph1":"Hematology","graph2":"Approved FDF","graph3":"Aspen Pharmacare Holdings","amount2":0,"highestDevelopmentShortName":"","therapeuticAreaShortName":"Hematology","amount2New":0,"dosageForm":"Undisclosed","sponsorNew":"Aspen Pharmacare Holdings \/ Viatris","highestDevelopmentStatusID":"15","companyTruncated":"Aspen Pharmacare Holdings \/ Viatris"}]

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01

Lead Product(s) : Rivaroxaban

Therapeutic Area : Hematology

Study Phase : Approved FDF

Sponsor : Inapplicable

Deal Size : Inapplicable

Deal Type : Inapplicable

Details : Xarelto-Generic (rivaroxaban) is a factor Xa inhibitor, anticoagulant small molecule drug. It is indicated for the treatment of deep vein thrombosis, pulmonary embolism & venous thromboembolism.

Product Name : Xarelto-Generic

Product Type : Other Small Molecule

Upfront Cash : Inapplicable

September 04, 2024

Lead Product(s) : Rivaroxaban

Therapeutic Area : Hematology

Highest Development Status : Approved FDF

Sponsor : Inapplicable

Deal Size : Inapplicable

Deal Type : Inapplicable

Tiefenbacher Compnay Banner

02

Lead Product(s) : Sutimlimab

Therapeutic Area : Hematology

Study Phase : Approved FDF

Sponsor : Recordati

Deal Size : $1,075.0 million

Deal Type : Acquisition

Details : Recordati will acquire the global rights to Enjaymo (sutimlimab), a biologic and the only approved targeted product for cold agglutinin disease, a rare B-cell lymphoproliferative disorder.

Product Name : Enjaymo

Product Type : Antibody

Upfront Cash : $825.0 million

April 10, 2024

Lead Product(s) : Sutimlimab

Therapeutic Area : Hematology

Highest Development Status : Approved FDF

Sponsor : Recordati

Deal Size : $1,075.0 million

Deal Type : Acquisition

Sanofi Company Banner

03

Lead Product(s) : Rivaroxaban

Therapeutic Area : Hematology

Study Phase : Approved FDF

Sponsor : Inapplicable

Deal Size : Inapplicable

Deal Type : Inapplicable

Details : Xarelto-Generic (rivaroxaban) is a factor Xa inhibitor, anticoagulant small molecule drug. It is indicated for the treatment of deep vein thrombosis, pulmonary embolism & venous thromboembolism.

Product Name : Xarelto-Generic

Product Type : Other Small Molecule

Upfront Cash : Inapplicable

November 16, 2023

Lead Product(s) : Rivaroxaban

Therapeutic Area : Hematology

Highest Development Status : Approved FDF

Sponsor : Inapplicable

Deal Size : Inapplicable

Deal Type : Inapplicable

Tiefenbacher Compnay Banner

04

Lead Product(s) : Sutimlimab

Therapeutic Area : Hematology

Study Phase : Approved FDF

Sponsor : Inapplicable

Deal Size : Inapplicable

Deal Type : Inapplicable

Details : Enjaymo (sutimlimab) is a humanized monoclonal antibody that is designed to selectively target and inhibit C1s in the classical complement pathway, which is part of the innate immune system. Enjaymo inhibits the activation of the complement cascade in th...

Product Name : Enjaymo

Product Type : Antibody

Upfront Cash : Inapplicable

November 17, 2022

Lead Product(s) : Sutimlimab

Therapeutic Area : Hematology

Highest Development Status : Approved FDF

Sponsor : Inapplicable

Deal Size : Inapplicable

Deal Type : Inapplicable

Sanofi Company Banner

05

Lead Product(s) : RLYB-331

Therapeutic Area : Hematology

Study Phase : Preclinical

Sponsor : Rallybio

Deal Size : Undisclosed

Deal Type : Licensing Agreement

Details : Rallybio plans to prosecute preclinical activities for KY1066/RLYB331 including CMC, and dose-range finding and toxicity studies, which will then support transition of the asset into clinical development.

Product Name : RLYB-331

Product Type : Antibody

Upfront Cash : $3.0 million

October 05, 2022

Lead Product(s) : RLYB-331

Therapeutic Area : Hematology

Highest Development Status : Preclinical

Sponsor : Rallybio

Deal Size : Undisclosed

Deal Type : Licensing Agreement

Sanofi Company Banner

06

Lead Product(s) : Sutimlimab

Therapeutic Area : Hematology

Study Phase : Approved FDF

Sponsor : Inapplicable

Deal Size : Inapplicable

Deal Type : Inapplicable

Details : Enjaymo (sutimlimab) is a humanized monoclonal antibody. By blocking C1s, Enjaymo inhibits the activation of the complement cascade in the immune system and inhibits C1-activated hemolysis in CAD to prevent the abnormal destruction of healthy RBCs.

Product Name : Enjaymo

Product Type : Antibody

Upfront Cash : Inapplicable

September 16, 2022

Lead Product(s) : Sutimlimab

Therapeutic Area : Hematology

Highest Development Status : Approved FDF

Sponsor : Inapplicable

Deal Size : Inapplicable

Deal Type : Inapplicable

Sanofi Company Banner

07

Lead Product(s) : Sutimlimab

Therapeutic Area : Hematology

Study Phase : Approved FDF

Sponsor : Inapplicable

Deal Size : Inapplicable

Deal Type : Inapplicable

Details : Enjaymo™ (sutimlimab) is a humanized monoclonal antibody that is designed to selectively target and inhibit C1s in the classical complement pathway, which is part of the innate immune system.

Product Name : Enjaymo

Product Type : Antibody

Upfront Cash : Inapplicable

September 16, 2022

Lead Product(s) : Sutimlimab

Therapeutic Area : Hematology

Highest Development Status : Approved FDF

Sponsor : Inapplicable

Deal Size : Inapplicable

Deal Type : Inapplicable

Sanofi Company Banner

08

Lead Product(s) : Rivaroxaban

Therapeutic Area : Hematology

Study Phase : Approved FDF

Sponsor : Inapplicable

Deal Size : Inapplicable

Deal Type : Inapplicable

Details : Xarelto-Generic (rivaroxaban) is a factor Xa inhibitor, anticoagulant small molecule drug. It is indicated for the treatment of deep vein thrombosis, pulmonary embolism & venous thromboembolism.

Product Name : Xarelto-Generic

Product Type : Other Small Molecule

Upfront Cash : Inapplicable

July 15, 2022

Lead Product(s) : Rivaroxaban

Therapeutic Area : Hematology

Highest Development Status : Approved FDF

Sponsor : Inapplicable

Deal Size : Inapplicable

Deal Type : Inapplicable

Tiefenbacher Compnay Banner

09

Lead Product(s) : Sutimlimab

Therapeutic Area : Hematology

Study Phase : Approved FDF

Sponsor : Inapplicable

Deal Size : Inapplicable

Deal Type : Inapplicable

Details : Enjaymo, selectively target and inhibit C1s is the only approved treatment to decrease the need for red blood cell transfusion due to hemolysis, the destruction of red blood cells, in adults with cold agglutinin disease.

Product Name : Enjaymo

Product Type : Antibody

Upfront Cash : Inapplicable

April 02, 2022

Lead Product(s) : Sutimlimab

Therapeutic Area : Hematology

Highest Development Status : Approved FDF

Sponsor : Inapplicable

Deal Size : Inapplicable

Deal Type : Inapplicable

Sanofi Company Banner

10

Lead Product(s) : Sutimlimab

Therapeutic Area : Hematology

Study Phase : Phase III

Sponsor : Inapplicable

Deal Size : Inapplicable

Deal Type : Inapplicable

Details : The CADENZA trial is a Phase 3, randomized, double-blind, placebo-controlled study to assess the efficacy and safety of sutimlimab in patients with CAD without a recent history of blood transfusion (within the past 6 months).

Product Name : Enjaymo

Product Type : Antibody

Upfront Cash : Inapplicable

November 06, 2021

Lead Product(s) : Sutimlimab

Therapeutic Area : Hematology

Highest Development Status : Phase III

Sponsor : Inapplicable

Deal Size : Inapplicable

Deal Type : Inapplicable

Sanofi Company Banner