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Pharmaceuticals","amount2":0,"highestDevelopmentShortName":"Approved","therapeuticAreaShortName":"Hematology","amount2New":0,"dosageForm":"","sponsorNew":"Nexus Pharmaceuticals \/ Not Applicable","highestDevelopmentStatusID":"12","companyTruncated":"Nexus Pharmaceuticals \/ Not Applicable"},{"orgOrder":0,"company":"Coherus Biosciences","sponsor":"Intas Pharmaceuticals","pharmaFlowCategory":"D","therapeuticArea":"Hematology","country":"","productType":"Large molecule","year":"2024","type":"Divestment","leadProduct":"Pegfilgrastim","moa":"","graph1":"Hematology","graph2":"Approved","graph3":"Coherus Biosciences","amount2":0.56000000000000005,"highestDevelopmentShortName":"Approved","therapeuticAreaShortName":"Hematology","amount2New":0.56000000000000005,"dosageForm":"","sponsorNew":"Coherus Biosciences \/ Intas Pharmaceuticals","highestDevelopmentStatusID":"12","companyTruncated":"Coherus Biosciences \/ Intas Pharmaceuticals"},{"orgOrder":0,"company":"Akebia Therapeutics","sponsor":"Not Applicable","pharmaFlowCategory":"DU","therapeuticArea":"Nephrology","country":"","productType":"Small molecule","year":"2024","type":"Not Applicable","leadProduct":"Vadadustat","moa":"","graph1":"Hematology","graph2":"Approved","graph3":"Akebia Therapeutics","amount2":0,"highestDevelopmentShortName":"Approved","therapeuticAreaShortName":"Hematology","amount2New":0,"dosageForm":"","sponsorNew":"Akebia Therapeutics \/ Not Applicable","highestDevelopmentStatusID":"12","companyTruncated":"Akebia Therapeutics \/ Not Applicable"}]

    Find Approved Hematology Drugs in Clinical Development

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                            01

                            Aucta Pharmaceuticals

                            U.S.A
                            DCAT Week
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                            Lead Product(s) : Deferasirox

                            Therapeutic Area : Hematology

                            Study Phase : Approved

                            Sponsor : Oakrum Pharma, LLC

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

                            DEALS_DEV arrow-down

                            Oakrum Pharma and Aucta Pharma Announce U.S. FDA Approval of Generic Version of JADENU® Sprinkle (Deferasirox...

                            Details : JADENU (deferasirox) tablets for oral use and JADENU® Sprinkle (deferasirox) granules are indicated for the treatment of chronic iron overload due to blood transfusions (transfusional hemosiderosis) in patients 2 years of age and older.

                            Product Name : Jadenu

                            Product Type : Small molecule

                            Upfront Cash : Not Applicable

                            March 22, 2021

                            Lead Product(s) : Deferasirox

                            Therapeutic Area : Hematology

                            Highest Development Status : Approved

                            Sponsor : Oakrum Pharma, LLC

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

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                            02

                            Coherus Biosciences

                            U.S.A arrow
                            RNA Therapeutics
                            Not Confirmed

                            Coherus Biosciences

                            U.S.A arrow
                            RNA Therapeutics
                            Not Confirmed
                            • fda
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                            Lead Product(s) : Pegfilgrastim

                            Therapeutic Area : Hematology

                            Study Phase : Approved

                            Sponsor : Intas Pharmaceuticals

                            Deal Size : $558.4 million

                            Deal Type : Divestment

                            DEALS_DEV arrow-down

                            Coherus Divests UDENYCA® Franchise to Intas Pharmaceuticals for Up to $558M

                            Details : The agreement aims to divest Udenyca (pegfilgrastim), a biosimilar of Neulasta, used to help reduce the chance of infection due to a low white blood cell count.

                            Product Name : Udenyca

                            Product Type : Large molecule

                            Upfront Cash : $483.4 million

                            December 03, 2024

                            Lead Product(s) : Pegfilgrastim

                            Therapeutic Area : Hematology

                            Highest Development Status : Approved

                            Sponsor : Intas Pharmaceuticals

                            Deal Size : $558.4 million

                            Deal Type : Divestment

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                            03

                            Nexus Pharmaceuticals

                            U.S.A arrow
                            RNA Therapeutics
                            Not Confirmed

                            Nexus Pharmaceuticals

                            U.S.A arrow
                            RNA Therapeutics
                            Not Confirmed
                            • fda
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                            Lead Product(s) : Methylene Blue

                            Therapeutic Area : Hematology

                            Study Phase : Approved

                            Sponsor : Not Applicable

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

                            DEALS_DEV arrow-down

                            Nexus Pharmaceuticals Receives FDA Approval for Methylene Blue Injection, USP

                            Details : The US FDA approved Methylene Blue Injection, USP (methylene blue). It is an oxidation-reduction agent that offers treatment of acquired methemoglobinemia.

                            Product Name : Methylene Blue Injection, USP

                            Product Type : Small molecule

                            Upfront Cash : Not Applicable

                            November 26, 2024

                            Lead Product(s) : Methylene Blue

                            Therapeutic Area : Hematology

                            Highest Development Status : Approved

                            Sponsor : Not Applicable

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

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                            04

                            Rigel Pharmaceuticals

                            U.S.A arrow
                            RNA Therapeutics
                            Not Confirmed

                            Rigel Pharmaceuticals

                            U.S.A arrow
                            RNA Therapeutics
                            Not Confirmed
                            • fda
                            • EDQM
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                            Lead Product(s) : Fostamatinib Disodium Hexahydrate

                            Therapeutic Area : Hematology

                            Study Phase : Approved

                            Sponsor : Optime Care

                            Deal Size : Undisclosed

                            Deal Type : Agreement

                            DEALS_DEV arrow-down

                            Optime Care Expands TAVALISSE® Distribution with Rigel Pharmaceuticals

                            Details : Under the agreement, Optime Care will commercialize three Rigel products, which includes Tavalisse (fostamatinib disodium hexahydrate), indicated for the treatment of thrombocytopenia.

                            Product Name : Tavalisse

                            Product Type : Small molecule

                            Upfront Cash : Undisclosed

                            October 16, 2024

                            Lead Product(s) : Fostamatinib Disodium Hexahydrate

                            Therapeutic Area : Hematology

                            Highest Development Status : Approved

                            Sponsor : Optime Care

                            Deal Size : Undisclosed

                            Deal Type : Agreement

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                            05

                            Akebia Therapeutics

                            U.S.A arrow
                            RNA Therapeutics
                            Not Confirmed

                            Akebia Therapeutics

                            U.S.A arrow
                            RNA Therapeutics
                            Not Confirmed
                            • fda
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                            Lead Product(s) : Vadadustat

                            Therapeutic Area : Hematology

                            Study Phase : Approved

                            Sponsor : U.S. Renal Care

                            Deal Size : Undisclosed

                            Deal Type : Agreement

                            DEALS_DEV arrow-down

                            Akebia And U.S. Renal Care Sign Contract For Vafseo® in Dialysis Patients

                            Details : The agreement aims to enable access to Vafseo (vadadustat), a once-daily oral hypoxia-inducible factor prolyl hydroxylase inhibitor, for patients on dialysis.

                            Product Name : Vafseo

                            Product Type : Small molecule

                            Upfront Cash : Undisclosed

                            October 07, 2024

                            Lead Product(s) : Vadadustat

                            Therapeutic Area : Hematology

                            Highest Development Status : Approved

                            Sponsor : U.S. Renal Care

                            Deal Size : Undisclosed

                            Deal Type : Agreement

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                            06

                            Lupin Ltd

                            India arrow
                            RNA Therapeutics
                            Not Confirmed

                            Lupin Ltd

                            India arrow
                            RNA Therapeutics
                            Not Confirmed
                            • fda
                            • EDQM
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                            Lead Product(s) : Pegfilgrastim

                            Therapeutic Area : Hematology

                            Study Phase : Approved

                            Sponsor : Not Applicable

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

                            DEALS_DEV arrow-down

                            Lupin Gains Health Canada Approval for Biosimilar Pegfilgrastim

                            Details : Armlupeg (pegfilgrastim) is a biosimilar of Neulasta, that acts as a G-CSF agonist & it is indicated for the treatment of patients suffering from febrile neutropenia.

                            Product Name : Armlupeg

                            Product Type : Large molecule

                            Upfront Cash : Not Applicable

                            August 23, 2024

                            Lead Product(s) : Pegfilgrastim

                            Therapeutic Area : Hematology

                            Highest Development Status : Approved

                            Sponsor : Not Applicable

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

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                            07

                            Octapharma

                            Switzerland arrow
                            RNA Therapeutics
                            Not Confirmed

                            Octapharma

                            Switzerland arrow
                            RNA Therapeutics
                            Not Confirmed
                            • fda
                            • EDQM
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                            Lead Product(s) : Fibrinogen

                            Therapeutic Area : Hematology

                            Study Phase : Approved

                            Sponsor : Not Applicable

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

                            DEALS_DEV arrow-down

                            FDA Approves Fibryga® for Fibrinogen Supplementation in Acquired Deficiency

                            Details : Fibryga is a fibrinogen concentrate which acts as as fibrinogen replacement therapy. It is approved for the treatment of acquired fibrinogen deficiency (AFD).

                            Product Name : Fibryga

                            Product Type : Large molecule

                            Upfront Cash : Not Applicable

                            August 01, 2024

                            Lead Product(s) : Fibrinogen

                            Therapeutic Area : Hematology

                            Highest Development Status : Approved

                            Sponsor : Not Applicable

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

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                            08

                            Gyre Therapeutics

                            U.S.A arrow
                            RNA Therapeutics
                            Not Confirmed

                            Gyre Therapeutics

                            U.S.A arrow
                            RNA Therapeutics
                            Not Confirmed
                            • fda
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                            Lead Product(s) : Avatrombopag Maleate

                            Therapeutic Area : Hematology

                            Study Phase : Approved

                            Sponsor : Nanjing Healthnice Pharmaceutical Technology

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

                            DEALS_DEV arrow-down

                            Gyre Therapeutics Gets NMPA Approval for Avatrombopag in CLD-Associated Thrombocytopenia

                            Details : Avatrombopag Maleate, a thrombopoietin receptor agonist is approved by NMPA china. It is given orally for the treatment of thrombocytopenia associated with chronic liver disease.

                            Product Name : Undisclosed

                            Product Type : Small molecule

                            Upfront Cash : Not Applicable

                            July 02, 2024

                            Lead Product(s) : Avatrombopag Maleate

                            Therapeutic Area : Hematology

                            Highest Development Status : Approved

                            Sponsor : Nanjing Healthnice Pharmaceutical Technology

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

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                            09

                            Mitsubishi Tanabe Pharma

                            Japan arrow
                            RNA Therapeutics
                            Not Confirmed

                            Mitsubishi Tanabe Pharma

                            Japan arrow
                            RNA Therapeutics
                            Not Confirmed
                            • fda
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                            Lead Product(s) : Argatroban Monohydrate

                            Therapeutic Area : Hematology

                            Study Phase : Approved

                            Sponsor : Ethypharm

                            Deal Size : Undisclosed

                            Deal Type : Acquisition

                            DEALS_DEV arrow-down

                            Acquisition of Argatroban Business in Europe

                            Details : Ethypharm acquired Mitsubishi Tanabe's selective antithrombin agent Arganova (argatroban monohydrate) in Europe. It is indicated for the treatment of heparin-induced thrombocytopenia type II.

                            Product Name : Arganova

                            Product Type : Small molecule

                            Upfront Cash : Undisclosed

                            June 17, 2024

                            Lead Product(s) : Argatroban Monohydrate

                            Therapeutic Area : Hematology

                            Highest Development Status : Approved

                            Sponsor : Ethypharm

                            Deal Size : Undisclosed

                            Deal Type : Acquisition

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                            10

                            Nora Pharma

                            Canada arrow
                            RNA Therapeutics
                            Not Confirmed

                            Nora Pharma

                            Canada arrow
                            RNA Therapeutics
                            Not Confirmed
                            • fda
                            • EDQM
                            • WHO-GMP
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                            Lead Product(s) : Pegfilgrastim

                            Therapeutic Area : Hematology

                            Study Phase : Approved

                            Sponsor : Not Applicable

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

                            DEALS_DEV arrow-down

                            Sunshine Biopharma's Nora Pharma Receives Approval for Niopeg(R) Biosimilar

                            Details : Niopeg (pegfilgrastim) is an FDA-approved G-CSF agonist for treating febrile neutropenia in patients with non-myeloid malignancies receiving myelosuppressive chemotherapy.

                            Product Name : Niopeg

                            Product Type : Large molecule

                            Upfront Cash : Not Applicable

                            April 19, 2024

                            Lead Product(s) : Pegfilgrastim

                            Therapeutic Area : Hematology

                            Highest Development Status : Approved

                            Sponsor : Not Applicable

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

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