Lead Product(s) : Stem Cell-derived Therapy
Therapeutic Area : Hematology
Study Phase : IND Enabling
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Regen BioPharma, Inc. Expands Vision for Phase 1 Clinical Trial of HemaXellerate™
Details : HemaXellerate is an innovative stem cell-derived therapy, designed to stimulate bone marrow regeneration, it has already received FDA clearance for treating aplastic anemia.
Brand Name : HemaXellerate
Molecule Type : Cell and Gene therapy
Upfront Cash : Not Applicable
November 19, 2024
Lead Product(s) : Stem Cell-derived Therapy
Therapeutic Area : Hematology
Highest Development Status : IND Enabling
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Lead Product(s) : Interferon Alfa
Therapeutic Area : Hematology
Study Phase : IND Enabling
Sponsor : Lind Partners
Deal Size : $1.7 million
Deal Type : Financing
Ainos Announces $1.75 Million Follow-On Funding
Details : Veldona (interferon alfa) is progressing towards IND applications for human drug candidates and co-development of VOC sensing tech using AI Nose.
Brand Name : Veldona
Molecule Type : Large molecule
Upfront Cash : Undisclosed
January 24, 2024
Lead Product(s) : Interferon Alfa
Therapeutic Area : Hematology
Highest Development Status : IND Enabling
Sponsor : Lind Partners
Deal Size : $1.7 million
Deal Type : Financing
Lead Product(s) : MWTX-001
Therapeutic Area : Hematology
Study Phase : IND Enabling
Sponsor : Disc medicine
Deal Size : $412.5 million
Deal Type : Licensing Agreement
Details : Under the terms of the agreement, Disc will obtain exclusive rights to develop and commercialize 9MW3011. MWTx 01 is a recombinant monoclonal antibody targeting a key regulator in the iron homeostasis pathway, developed to treat iron overload disorders.
Brand Name : MWTX-001
Molecule Type : Large molecule
Upfront Cash : $10.0 million
January 20, 2023
Lead Product(s) : MWTX-001
Therapeutic Area : Hematology
Highest Development Status : IND Enabling
Sponsor : Disc medicine
Deal Size : $412.5 million
Deal Type : Licensing Agreement
Lead Product(s) : CT-001
Therapeutic Area : Hematology
Study Phase : IND Enabling
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Details : CT-001 is an engineered version of FVIIa that is designed to address the limitations of the recombinant FVIIa, approved for use in Hemophilia A and B patients with inhibitors, congenital FVII deficiency.
Brand Name : CT-001
Molecule Type : Large molecule
Upfront Cash : Not Applicable
November 16, 2022
Lead Product(s) : CT-001
Therapeutic Area : Hematology
Highest Development Status : IND Enabling
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Lead Product(s) : CT-001
Therapeutic Area : Hematology
Study Phase : IND Enabling
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Details : CT-001 is an engineered version of clotting factor FVIIa designed to address safety and efficacy limitations of recombinant FVIIa is approved for use in Hemophilia A and B patients with inhibitors.
Brand Name : CT-001
Molecule Type : Large molecule
Upfront Cash : Not Applicable
July 12, 2022
Lead Product(s) : CT-001
Therapeutic Area : Hematology
Highest Development Status : IND Enabling
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Lead Product(s) : STP122G
Therapeutic Area : Hematology
Study Phase : IND Enabling
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Details : STP122G is in early-stage development as an anticoagulant in settings where antithrombotic therapeutics are needed such as stroke patients and orthopedic surgery patients. STP122G targets Factor XI, a plasma glycoprotein that is primarily synthesized in ...
Brand Name : STP122G
Molecule Type : Large molecule
Upfront Cash : Not Applicable
June 21, 2022
Lead Product(s) : STP122G
Therapeutic Area : Hematology
Highest Development Status : IND Enabling
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Lead Product(s) : STP122G
Therapeutic Area : Hematology
Study Phase : IND Enabling
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Details : STP122G comprises RNAi triggers targeting Factor XI. Factor XI is a plasma glycoprotein that is primarily synthesized in the liver and is part of the coagulation cascade, playing a role in clot stabilization and expansion.
Brand Name : STP122G
Molecule Type : Peptide
Upfront Cash : Not Applicable
May 11, 2022
Lead Product(s) : STP122G
Therapeutic Area : Hematology
Highest Development Status : IND Enabling
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Lead Product(s) : OMS906
Therapeutic Area : Hematology
Study Phase : IND Enabling
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Omeros’ Investigational New Drug Application for OMS906 Cleared by FDA
Details : OMS906 is the company’s lead human monoclonal antibody targeting mannan-binding lectin-associated serine protease-3 (MASP-3), the key activator of the complement system’s alternative pathway.
Brand Name : OMS906
Molecule Type : Large molecule
Upfront Cash : Not Applicable
August 31, 2020
Lead Product(s) : OMS906
Therapeutic Area : Hematology
Highest Development Status : IND Enabling
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
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