Lead Product(s) : SRSD107
Therapeutic Area : Hematology
Study Phase : Phase I
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
Sirius Shares Promising Phase 1 Data for Factor XI siRNA in Thromboembolic Disorders
Details : SRSD107 is a Factor XI inhibitor siRNA drug candidate, which is currently being evaluated for the treatment of thromboembolic disorders.
Product Name : SRSD107
Product Type : Oligonucleotide
Upfront Cash : Inapplicable
December 10, 2024
Lead Product(s) : SRSD107
Therapeutic Area : Hematology
Highest Development Status : Phase I
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
Lead Product(s) : BBI-001
Therapeutic Area : Hematology
Study Phase : Phase I
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
Bond Biosciences Advances BBI-001 for Iron Overload After FDA Meeting
Details : BBI-001 is a novel oral drug designed to inhibit iron absorption by forming a selective iron chelate in the digestive tract, currently evaluated for hereditary hemochromatosis.
Product Name : BBI-001
Product Type : Other Small Molecule
Upfront Cash : Inapplicable
November 01, 2024
Lead Product(s) : BBI-001
Therapeutic Area : Hematology
Highest Development Status : Phase I
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
Lead Product(s) : STP122G
Therapeutic Area : Hematology
Study Phase : Phase I
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
Sirnaomics Reports Positive Results for GalNAc-Based RNAi Therapeutic STP122G
Details : STP122G is a GalNAc-based RNAi therapeutic, SC formulation, targetting Factor XI. It is in early-stage development as an anticoagulant, utilizing company's proprietary GalAhead platform.
Product Name : STP122G
Product Type : Oligonucleotide
Upfront Cash : Inapplicable
August 07, 2024
Lead Product(s) : STP122G
Therapeutic Area : Hematology
Highest Development Status : Phase I
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
Lead Product(s) : Tecarfarin
Therapeutic Area : Hematology
Study Phase : Phase I
Sponsor : Abbott Laboratories
Deal Size : Undisclosed
Deal Type : Collaboration
Cadrenal and Abbott Collaborate on Novel Anticoagulant Tecarfarin for LVAD Patients
Details : The collaboration aims to advance the novel anticoagulant ATI-5923 (tecarfarin), designed to prevent heart attacks, strokes, and deaths due to blood clots in patients with implanted cardiac devices.
Product Name : ATI-5923
Product Type : Other Small Molecule
Upfront Cash : Undisclosed
June 08, 2024
Lead Product(s) : Tecarfarin
Therapeutic Area : Hematology
Highest Development Status : Phase I
Sponsor : Abbott Laboratories
Deal Size : Undisclosed
Deal Type : Collaboration
Lead Product(s) : SCB-219M
Therapeutic Area : Hematology
Study Phase : Phase I
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
Details : SCB-219M is an innovative TPO-RA mimetic bispecific Fc-fusion protein produced from CHO cells. It is under phase 1 clinical development for the treatment of cancer patients with chemotherapy-induced thrombocytopenia.
Product Name : SCB-219M
Product Type : Protein
Upfront Cash : Inapplicable
December 28, 2023
Lead Product(s) : SCB-219M
Therapeutic Area : Hematology
Highest Development Status : Phase I
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
Lead Product(s) : ANX1502
Therapeutic Area : Hematology
Study Phase : Phase I
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
Details : ANX1502 is a classical complement pathway inhibitor, small molecule drug candidate, which is currently being evaluated for the treatment of patients with cold agglutinin disease.
Product Name : ANX1502
Product Type : Other Small Molecule
Upfront Cash : Inapplicable
December 20, 2023
Lead Product(s) : ANX1502
Therapeutic Area : Hematology
Highest Development Status : Phase I
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
Lead Product(s) : Spray-Dried Plasma
Therapeutic Area : Hematology
Study Phase : Phase I
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
Velico Medical Begins Clinical Trial on Spray Dried Plasma
Details : FrontlineODP(OnDemandPlasma) spray which is investigated in first in-human clinical trial Phase I safety trial for the prevention of trauma-induced coagulopathy.
Product Name : FrontlineODP
Product Type : Other Large Molecule
Upfront Cash : Inapplicable
December 07, 2023
Lead Product(s) : Spray-Dried Plasma
Therapeutic Area : Hematology
Highest Development Status : Phase I
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
Lead Product(s) : SRSD107
Therapeutic Area : Hematology
Study Phase : Phase I
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
Sirius Therapeutics Announces Submission to Begin First Clinical Trial of Factor XI siRNA
Details : SRSD107 is a novel double-stranded small interfering ribonucleic acid (siRNA). it specifically targets coagulation factor XI (FXI) mRNA and inhibits FXI protein expression, thereby blocking the intrinsic coagulation pathway and promoting anticoagulant/an...
Product Name : SRSD107
Product Type : Oligonucleotide
Upfront Cash : Inapplicable
September 11, 2023
Lead Product(s) : SRSD107
Therapeutic Area : Hematology
Highest Development Status : Phase I
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
Lead Product(s) : BBI-001
Therapeutic Area : Hematology
Study Phase : Phase I
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
Details : BI-001 is a novel investigational new drug. It is a non-absorbed, oral therapeutic designed to rapidly form a strong and selective iron chelate in the digestive tract, thus inhibiting iron absorption in patients with symptomatic iron overload due to HH.
Product Name : BBI-001
Product Type : Other Small Molecule
Upfront Cash : Inapplicable
July 19, 2023
Lead Product(s) : BBI-001
Therapeutic Area : Hematology
Highest Development Status : Phase I
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
Lead Product(s) : TS23
Therapeutic Area : Hematology
Study Phase : Phase I
Sponsor : Translational Sciences
Deal Size : Undisclosed
Deal Type : Licensing Agreement
CSL Enters Into Strategic Option and License Agreement with Translational Sciences
Details : TS23 is a first-in-class anti-α2-antiplasmin monoclonal antibody, which is being developed to dissolve thrombi that cause serious conditions such as pulmonary embolism (PE) and acute ischemic stroke (AIS).
Product Name : TS23
Product Type : Antibody
Upfront Cash : Undisclosed
October 26, 2022
Lead Product(s) : TS23
Therapeutic Area : Hematology
Highest Development Status : Phase I
Sponsor : Translational Sciences
Deal Size : Undisclosed
Deal Type : Licensing Agreement