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Catalent"},{"orgOrder":0,"company":"Imago BioSciences","sponsor":"Not Applicable","pharmaFlowCategory":"DU","therapeuticArea":"Oncology","country":"","productType":"Small molecule","year":"2021","type":"Not Applicable","leadProduct":"Bomedemstat","moa":"LSD1","graph1":"Hematology","graph2":"Phase II","graph3":"Imago BioSciences","amount2":0,"highestDevelopmentShortName":"Ph II","therapeuticAreaShortName":"Hematology","amount2New":0,"dosageForm":"Oral","sponsorNew":"Imago BioSciences \/ Not Applicable","highestDevelopmentStatusID":"8","companyTruncated":"Imago BioSciences \/ Not Applicable"},{"orgOrder":0,"company":"Covis Pharma","sponsor":"Norgine","pharmaFlowCategory":"DU","therapeuticArea":"Hematology","country":"","productType":"Small molecule","year":"2021","type":"Not Applicable","leadProduct":"Ciraparantag","moa":"","graph1":"Hematology","graph2":"Phase II","graph3":"Covis Pharma","amount2":0,"highestDevelopmentShortName":"Ph 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LLC"},{"orgOrder":0,"company":"Ainos","sponsor":"Lind Partners","pharmaFlowCategory":"D","therapeuticArea":"Hematology","country":"","productType":"Large molecule","year":"2024","type":"Financing","leadProduct":"Interferon Alfa","moa":"","graph1":"Hematology","graph2":"Phase II","graph3":"Ainos","amount2":0,"highestDevelopmentShortName":"Ph II","therapeuticAreaShortName":"Hematology","amount2New":0,"dosageForm":"Troche\/Lozenge","sponsorNew":"Ainos \/ Lind Partners","highestDevelopmentStatusID":"8","companyTruncated":"Ainos \/ Lind Partners"},{"orgOrder":0,"company":"Ainos","sponsor":"Undisclosed","pharmaFlowCategory":"D","therapeuticArea":"Hematology","country":"","productType":"Large molecule","year":"2024","type":"Financing","leadProduct":"Interferon Alfa","moa":"","graph1":"Hematology","graph2":"Phase II","graph3":"Ainos","amount2":0.01,"highestDevelopmentShortName":"Ph II","therapeuticAreaShortName":"Hematology","amount2New":0.01,"dosageForm":"Troche\/Lozenge","sponsorNew":"Ainos \/ Undisclosed","highestDevelopmentStatusID":"8","companyTruncated":"Ainos \/ Undisclosed"}]

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                          01

                          Fi Europe 2024
                          Not Confirmed
                          Fi Europe 2024
                          Not Confirmed

                          Details : Rytstat (desidustat), first-of-its-kind oral tablet being investigated for the treatment for Sickle Cell Disease, in India.

                          Brand Name : Rytstat

                          Molecule Type : Small molecule

                          Upfront Cash : Not Applicable

                          October 14, 2024

                          Lead Product(s) : Desidustat

                          Therapeutic Area : Hematology

                          Highest Development Status : Phase II

                          Sponsor : ICMR

                          Deal Size : Not Applicable

                          Deal Type : Not Applicable

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                          02

                          Fi Europe 2024
                          Not Confirmed
                          Fi Europe 2024
                          Not Confirmed

                          Details : VLX-1005, a small molecule 12-LOX inhibitor, which is being evaluated for the treatment of heparin induced thrombocytopenia.

                          Brand Name : VLX-1005

                          Molecule Type : Small molecule

                          Upfront Cash : Not Applicable

                          August 14, 2024

                          Lead Product(s) : VLX-1005

                          Therapeutic Area : Hematology

                          Highest Development Status : Phase II

                          Sponsor : Not Applicable

                          Deal Size : Not Applicable

                          Deal Type : Not Applicable

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                          03

                          Fi Europe 2024
                          Not Confirmed
                          Fi Europe 2024
                          Not Confirmed

                          Details : BIOX-101 (Ir-CPI) is a FXIa inhibitor small molecule drug candidate, which is being evaluated for the treatment of patients with intracerebral hemorrhagic stroke.

                          Brand Name : BIOX-101

                          Molecule Type : Small molecule

                          Upfront Cash : Not Applicable

                          June 27, 2024

                          Lead Product(s) : Ir-CPI

                          Therapeutic Area : Hematology

                          Highest Development Status : Phase II

                          Sponsor : Not Applicable

                          Deal Size : Not Applicable

                          Deal Type : Not Applicable

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                          04

                          Fi Europe 2024
                          Not Confirmed
                          Fi Europe 2024
                          Not Confirmed

                          Details : The financing will be used to advance company's products including VELDONA (interferon alfa) which binds to type I interferon receptors (IFNAR). It is being evaluated for thrombocytopenia.

                          Brand Name : Veldona

                          Molecule Type : Large molecule

                          Upfront Cash : Undisclosed

                          May 07, 2024

                          Lead Product(s) : Interferon Alfa

                          Therapeutic Area : Hematology

                          Highest Development Status : Phase II

                          Sponsor : Undisclosed

                          Deal Size : $9.0 million

                          Deal Type : Financing

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                          05

                          Fi Europe 2024
                          Not Confirmed
                          Fi Europe 2024
                          Not Confirmed

                          Details : The net proceeds will advance KER-050, an investigational modified activin receptor type IIA ligand, in Phase 2 trials for myelodysplastic syndromes and myelofibrosis.

                          Brand Name : KER-050

                          Molecule Type : Large molecule

                          Upfront Cash : Undisclosed

                          January 09, 2024

                          Lead Product(s) : Elritercept

                          Therapeutic Area : Hematology

                          Highest Development Status : Phase II

                          Sponsor : Goldman Sachs & Co. LLC

                          Deal Size : $151.3 million

                          Deal Type : Public Offering

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                          06

                          Fi Europe 2024
                          Not Confirmed
                          Fi Europe 2024
                          Not Confirmed

                          Details : The net proceeds will advance KER-050, an investigational modified activin receptor type IIA ligand, in Phase 2 trials for myelodysplastic syndromes and myelofibrosis.

                          Brand Name : KER-050

                          Molecule Type : Large molecule

                          Upfront Cash : Undisclosed

                          January 03, 2024

                          Lead Product(s) : Elritercept

                          Therapeutic Area : Hematology

                          Highest Development Status : Phase II

                          Sponsor : Goldman Sachs & Co. LLC

                          Deal Size : $140.0 million

                          Deal Type : Public Offering

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                          07

                          Fi Europe 2024
                          Not Confirmed
                          Fi Europe 2024
                          Not Confirmed

                          Details : KER-047, is designed to selectively and potently inhibit ALK2, a TGF-β receptor. KER-047 is being developed for the treatment of functional iron deficiency which is a consequence of elevated ALK2 signaling, including the Company’s initial target, IRID...

                          Brand Name : KER-047

                          Molecule Type : Small molecule

                          Upfront Cash : Not Applicable

                          December 12, 2022

                          Lead Product(s) : KER-047

                          Therapeutic Area : Hematology

                          Highest Development Status : Phase II

                          Sponsor : Not Applicable

                          Deal Size : Not Applicable

                          Deal Type : Not Applicable

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                          08

                          Fi Europe 2024
                          Not Confirmed
                          Fi Europe 2024
                          Not Confirmed

                          Details : KER-047, is designed to selectively and potently inhibit activin receptor-like kinase-2, a TGF-β superfamily receptor. KER-047 is being developed for the treatment of functional iron deficiency which is a consequence of elevated ALK2 signaling.

                          Brand Name : KER-047

                          Molecule Type : Small molecule

                          Upfront Cash : Not Applicable

                          November 03, 2022

                          Lead Product(s) : KER-047

                          Therapeutic Area : Hematology

                          Highest Development Status : Phase II

                          Sponsor : Not Applicable

                          Deal Size : Not Applicable

                          Deal Type : Not Applicable

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                          09

                          Fi Europe 2024
                          Not Confirmed
                          Fi Europe 2024
                          Not Confirmed

                          Details : AG-946, is a novel small molecule that activates the enzyme pyruvate kinase which contributes to the production of energy in the RBC. By helping to increase energy, RBC functionality and survival may be improved.

                          Brand Name : AG-946

                          Molecule Type : Small molecule

                          Upfront Cash : Not Applicable

                          November 03, 2022

                          Lead Product(s) : Tebapivat

                          Therapeutic Area : Hematology

                          Highest Development Status : Phase II

                          Sponsor : Not Applicable

                          Deal Size : Not Applicable

                          Deal Type : Not Applicable

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                          10

                          Forma Therapeutics

                          Country arrow
                          Fi Europe 2024
                          Not Confirmed

                          Forma Therapeutics

                          Country arrow
                          Fi Europe 2024
                          Not Confirmed

                          Details : With the acquisition, Novo Nordisk will gain access to Forma’s lead development candidate, etavopivat being developed in SCD to expand presence in sickle cell disease, rare blood disorders and haemoglobinopathies.

                          Brand Name : FT-4202

                          Molecule Type : Small molecule

                          Upfront Cash : $1,100.0 million

                          September 01, 2022

                          Lead Product(s) : Etavopivat

                          Therapeutic Area : Hematology

                          Highest Development Status : Phase II

                          Sponsor : Novo Nordisk

                          Deal Size : $1,100.0 million

                          Deal Type : Acquisition

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