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                          Top Deals by Deal Size (USD bn)

                          01

                          German Wound Congress
                          Not Confirmed
                          German Wound Congress
                          Not Confirmed

                          Details : TAH3311 (apixaban) is a factor Xa inhibitor, anticoagulant small molecule drug. It is being investigated for the treatment of thromboembolic conditions.

                          Product Name : TAH3311

                          Product Type : HPAPI

                          Upfront Cash : Inapplicable

                          February 17, 2025

                          Lead Product(s) : Apixaban

                          Therapeutic Area : Hematology

                          Highest Development Status : Phase II

                          Sponsor : Inapplicable

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

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                          02

                          German Wound Congress
                          Not Confirmed
                          German Wound Congress
                          Not Confirmed

                          Details : The proceeds will allow the company to deliver full results from BIRCH, its Phase 2a trial of BIOX-101 (Ir-CPI) to treat intracerebral hemorrhage.

                          Product Name : BIOX-101

                          Product Type : Other Small Molecule

                          Upfront Cash : Undisclosed

                          February 12, 2025

                          Lead Product(s) : BIOX-101

                          Therapeutic Area : Hematology

                          Highest Development Status : Phase II

                          Sponsor : Undisclosed

                          Deal Size : $15.4 million

                          Deal Type : Series A Financing

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                          03

                          German Wound Congress
                          Not Confirmed
                          German Wound Congress
                          Not Confirmed

                          Details : TAH3311 (apixaban) is a factor Xa inhibitor, anticoagulant small molecule drug. It is being investigated for the treatment of thromboembolic conditions.

                          Product Name : TAH3311

                          Product Type : HPAPI

                          Upfront Cash : Inapplicable

                          January 21, 2025

                          Lead Product(s) : Apixaban

                          Therapeutic Area : Hematology

                          Highest Development Status : Phase II

                          Sponsor : Inapplicable

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

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                          04

                          German Wound Congress
                          Not Confirmed
                          German Wound Congress
                          Not Confirmed

                          Details : BIOX-101 (Ir-CPI) is a FXIa inhibitor small molecule drug candidate, which is being evaluated for the treatment of patients with intracerebral hemorrhagic stroke.

                          Product Name : BIOX-101

                          Product Type : Other Small Molecule

                          Upfront Cash : Inapplicable

                          December 19, 2024

                          Lead Product(s) : BIOX-101

                          Therapeutic Area : Hematology

                          Highest Development Status : Phase II

                          Sponsor : Inapplicable

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

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                          05

                          German Wound Congress
                          Not Confirmed
                          German Wound Congress
                          Not Confirmed

                          Details : REGN7508 is an antibody designed to maximize anticoagulant activity while minimizing bleeding risk, in patients with venous thromboembolism.

                          Product Name : REGN7508

                          Product Type : Other Large Molecule

                          Upfront Cash : Inapplicable

                          December 19, 2024

                          Lead Product(s) : REGN7508

                          Therapeutic Area : Hematology

                          Highest Development Status : Phase II

                          Sponsor : Inapplicable

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

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                          06

                          German Wound Congress
                          Not Confirmed
                          German Wound Congress
                          Not Confirmed

                          Details : The net proceeds will advance KER-050, an investigational modified activin receptor type IIA ligand, in Phase 2 trials for myelodysplastic syndromes and myelofibrosis.

                          Product Name : KER-050

                          Product Type : Protein

                          Upfront Cash : Undisclosed

                          September 01, 2024

                          Lead Product(s) : Elritercept

                          Therapeutic Area : Hematology

                          Highest Development Status : Phase II

                          Sponsor : Goldman Sachs & Co

                          Deal Size : $151.3 million

                          Deal Type : Public Offering

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                          07

                          German Wound Congress
                          Not Confirmed
                          German Wound Congress
                          Not Confirmed

                          Details : VLX-1005, a small molecule 12-LOX inhibitor, which is being evaluated for the treatment of heparin induced thrombocytopenia.

                          Product Name : VLX-1005

                          Product Type : Other Small Molecule

                          Upfront Cash : Inapplicable

                          August 14, 2024

                          Lead Product(s) : VLX-1005

                          Therapeutic Area : Hematology

                          Highest Development Status : Phase II

                          Sponsor : Inapplicable

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

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                          08

                          German Wound Congress
                          Not Confirmed
                          German Wound Congress
                          Not Confirmed

                          Details : The financing will be used to advance company's products including VELDONA (interferon alfa) which binds to type I interferon receptors (IFNAR). It is being evaluated for thrombocytopenia.

                          Product Name : Veldona

                          Product Type : Protein

                          Upfront Cash : Undisclosed

                          July 05, 2024

                          Lead Product(s) : Interferon Alpha

                          Therapeutic Area : Hematology

                          Highest Development Status : Phase II

                          Sponsor : Undisclosed

                          Deal Size : $9.0 million

                          Deal Type : Financing

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                          09

                          German Wound Congress
                          Not Confirmed
                          German Wound Congress
                          Not Confirmed

                          Details : BIOX-101 (Ir-CPI) is a FXIa inhibitor small molecule drug candidate, which is being evaluated for the treatment of patients with intracerebral hemorrhagic stroke.

                          Product Name : BIOX-101

                          Product Type : Other Small Molecule

                          Upfront Cash : Inapplicable

                          June 27, 2024

                          Lead Product(s) : BIOX-101

                          Therapeutic Area : Hematology

                          Highest Development Status : Phase II

                          Sponsor : Inapplicable

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

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                          10

                          German Wound Congress
                          Not Confirmed
                          German Wound Congress
                          Not Confirmed

                          Details : CGT9486 (bezuclastinib) is a selective tyrosine kinase inhibitor, designed to potently inhibit the KIT D816V mutation. It is being evaluated for the treatment of nonadvanced systemic mastocytosis.

                          Product Name : CGT9486

                          Product Type : Other Small Molecule

                          Upfront Cash : Inapplicable

                          June 14, 2024

                          Lead Product(s) : Bezuclastinib

                          Therapeutic Area : Hematology

                          Highest Development Status : Phase II

                          Sponsor : Inapplicable

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

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