Lead Product(s) : RLYB331
Therapeutic Area : Hematology
Study Phase : Preclinical
Sponsor : Rallybio
Deal Size : Undisclosed
Deal Type : Licensing Agreement
Details : Rallybio plans to prosecute preclinical activities for KY1066/RLYB331 including CMC, and dose-range finding and toxicity studies, which will then support transition of the asset into clinical development.
Product Name : KY1066
Product Type : Large molecule
Upfront Cash : $3.0 million
May 10, 2022
Lead Product(s) : RLYB331
Therapeutic Area : Hematology
Highest Development Status : Preclinical
Sponsor : Rallybio
Deal Size : Undisclosed
Deal Type : Licensing Agreement
Lead Product(s) : IMM–004
Therapeutic Area : Hematology
Study Phase : Preclinical
Sponsor : Novo Nordisk
Deal Size : Undisclosed
Deal Type : Partnership
IMMvention, Novo Nordisk Partner on Oral Sickle Cell, Chronic Disease Therapies
Details : The partnership will leverage IMMvention’s investigational small-molecule BACH1 inhibitors, IMM–004. It is being evaluating for the treatment of sickle cell disease.
Product Name : IMM–004
Product Type : Other Small Molecule
Upfront Cash : Undisclosed
January 22, 2025
Lead Product(s) : IMM–004
Therapeutic Area : Hematology
Highest Development Status : Preclinical
Sponsor : Novo Nordisk
Deal Size : Undisclosed
Deal Type : Partnership
Lead Product(s) : Losartan Potassium
Therapeutic Area : Hematology
Study Phase : Preclinical
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
Kwality Pharma Gains on Securing RCGM Approval for Erythropoietin
Details : Kwality Pharmaceuticals gains RCGM approval for preclinical toxicity studies of recombinant Erythropoietin, advancing its biologics portfolio and targeting CKD-related anemia treatment.
Product Name : Undisclosed
Product Type : Hormone
Upfront Cash : Inapplicable
January 02, 2025
Lead Product(s) : Losartan Potassium
Therapeutic Area : Hematology
Highest Development Status : Preclinical
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
Lead Product(s) : Undisclosed
Therapeutic Area : Hematology
Study Phase : Preclinical
Sponsor : Bill & Melinda Gates Foundation
Deal Size : $50.0 million
Deal Type : Funding
Tessera Therapeutics Invests in Sickle Cell Disease in Vivo Genetic Treatment
Details : The funding will be used to support the development of Tessera's in vivo program for sickle cell disease program into the clinic.
Product Name : Undisclosed
Product Type : Cell and Gene therapy
Upfront Cash : Undisclosed
December 18, 2024
Lead Product(s) : Undisclosed
Therapeutic Area : Hematology
Highest Development Status : Preclinical
Sponsor : Bill & Melinda Gates Foundation
Deal Size : $50.0 million
Deal Type : Funding
Lead Product(s) : OKL-1111
Therapeutic Area : Hematology
Study Phase : Preclinical
Sponsor : Broadview Ventures
Deal Size : $5.2 million
Deal Type : Financing
Alveron Secures €5M Seed Extension Financing for Intracranial Hemorrhage Therapy
Details : The financing aims to advance the development of its innovative drug, OKL-1111, for the treatment of intracranial haemorrhage.
Product Name : OKL-1111
Product Type : Small molecule
Upfront Cash : Undisclosed
December 06, 2024
Lead Product(s) : OKL-1111
Therapeutic Area : Hematology
Highest Development Status : Preclinical
Sponsor : Broadview Ventures
Deal Size : $5.2 million
Deal Type : Financing
Lead Product(s) : T-Cell Therapy
Therapeutic Area : Hematology
Study Phase : Preclinical
Sponsor : Bristol Myers Squibb
Deal Size : $3,610.0 million
Deal Type : Collaboration
Prime Medicine and Bristol Myers Partner On Ex Vivo T-Cell Therapies
Details : The collaboration combines Prime Medicine’s precise, multiplex gene editing capabilities with BMS’s broad expertise in development and commercialization of novel ex vivo T-cell therapies.
Product Name : Undisclosed
Product Type : Cell and Gene therapy
Upfront Cash : Undisclosed
September 30, 2024
Lead Product(s) : T-Cell Therapy
Therapeutic Area : Hematology
Highest Development Status : Preclinical
Sponsor : Bristol Myers Squibb
Deal Size : $3,610.0 million
Deal Type : Collaboration
Lead Product(s) : T-Cell-based Therapy
Therapeutic Area : Hematology
Study Phase : Preclinical
Sponsor : Bristol Myers Squibb
Deal Size : $3,610.0 million
Deal Type : Collaboration
BMS Pays Prime $110M to Form T-cell Therapy Pact
Details : Prime Medicine will design optimized Prime Editor reagents for a select number of targets, including reagents that use its Prime Assisted Site-Specific Integrase Gene Editing (PASSIGE™) technology.
Product Name : Undisclosed
Product Type : Cell and Gene therapy
Upfront Cash : $110.0 million
September 30, 2024
Lead Product(s) : T-Cell-based Therapy
Therapeutic Area : Hematology
Highest Development Status : Preclinical
Sponsor : Bristol Myers Squibb
Deal Size : $3,610.0 million
Deal Type : Collaboration
Lead Product(s) : Ex-vivo NK Cell Therapy
Therapeutic Area : Hematology
Study Phase : Preclinical
Sponsor : Sanofi
Deal Size : $1,240.0 million
Deal Type : Expanded Collaboration
Details : Under the collaboration, Sanofi receives an exclusive license to use Scribe’s CRISPR X-Editing (XE) genome editing technologies for the development of in vivo NK-cell therapies, including sickle cell disease.
Product Name : Undisclosed
Product Type : Cell and Gene therapy
Upfront Cash : $40.0 million
July 17, 2023
Lead Product(s) : Ex-vivo NK Cell Therapy
Therapeutic Area : Hematology
Highest Development Status : Preclinical
Sponsor : Sanofi
Deal Size : $1,240.0 million
Deal Type : Expanded Collaboration
Lead Product(s) : Undisclosed
Therapeutic Area : Hematology
Study Phase : Preclinical
Sponsor : DanausGT Biotechnology
Deal Size : Undisclosed
Deal Type : Collaboration
Details : This collaboration will accelerate the development of innovative therapeutics for the treatment of some diseases such as blood, skin, and liver-related diseases.
Product Name : Undisclosed
Product Type : Cell and Gene therapy
Upfront Cash : Undisclosed
March 02, 2023
Lead Product(s) : Undisclosed
Therapeutic Area : Hematology
Highest Development Status : Preclinical
Sponsor : DanausGT Biotechnology
Deal Size : Undisclosed
Deal Type : Collaboration
Lead Product(s) : Blood Stem cell-based Therapy
Therapeutic Area : Hematology
Study Phase : Preclinical
Sponsor : Undisclosed
Deal Size : $62.0 million
Deal Type : Series B Financing
Fly Like an Eagle: Garuda Brings in A $62M Series B
Details : The Series B funds will funnel into two programs Blood stem cell-based therapy, slated to hit the clinic in 2024 - transfusion-dependent beta-thalassemia (TDBT) in Europe and bone marrow failure syndrome in Europe, South America and North America
Product Name : Undisclosed
Product Type : Cell and Gene therapy
Upfront Cash : Undisclosed
February 07, 2023
Lead Product(s) : Blood Stem cell-based Therapy
Therapeutic Area : Hematology
Highest Development Status : Preclinical
Sponsor : Undisclosed
Deal Size : $62.0 million
Deal Type : Series B Financing