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    [{"orgOrder":0,"company":"Hemogenyx Pharmaceuticals","sponsor":"Hemogenyx Pharmaceuticals","pharmaFlowCategory":"D","therapeuticArea":"Immunology","country":"","productType":"Undisclosed","year":"2020","type":"Agreement","leadProduct":"Undisclosed","moa":"","graph1":"Immunology","graph2":"Discovery","graph3":"Hemogenyx Pharmaceuticals","amount2":0,"highestDevelopmentShortName":"Discovery","therapeuticAreaShortName":"Immunology","amount2New":0,"dosageForm":"","sponsorNew":"Hemogenyx Pharmaceuticals \/ Hemogenyx Pharmaceuticals","highestDevelopmentStatusID":"2","companyTruncated":"Hemogenyx Pharmaceuticals \/ Hemogenyx Pharmaceuticals"},{"orgOrder":0,"company":"Hemogenyx Pharmaceuticals","sponsor":"Hemogenyx Pharmaceuticals","pharmaFlowCategory":"D","therapeuticArea":"Oncology","country":"U.S.A","productType":"Cell and Gene therapy","year":"2020","type":"Agreement","leadProduct":"CAR-T therapy","moa":"","graph1":"Oncology","graph2":"Undisclosed","graph3":"Hemogenyx 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                            01

                            Hemogenyx Pharmaceuticals

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                            Lead Product(s) : HEMO-CAR-T Cell Therapy

                            Therapeutic Area : Oncology

                            Study Phase : IND Enabling

                            Sponsor : Prevail Partners

                            Deal Size : $0.3 million

                            Deal Type : Financing

                            DEALS_DEV arrow-down

                            Hemogenyx Pharmaceuticals PLC Announces Strategic Investment from Prevail Partners, LLC

                            Details : THe proceeds will be used in clinical services and technologies for the Company's upcoming Phase I of an anti-FLT3 CAR-T cells in pediatric subjects with R/R AML and a subset of ALL.

                            Brand Name : Undisclosed

                            Molecule Type : Cell and Gene therapy

                            Upfront Cash : Undisclosed

                            October 02, 2024

                            Lead Product(s) : HEMO-CAR-T Cell Therapy

                            Therapeutic Area : Oncology

                            Highest Development Status : IND Enabling

                            Sponsor : Prevail Partners

                            Deal Size : $0.3 million

                            Deal Type : Financing

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                            02

                            Hemogenyx Pharmaceuticals

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                            Lead Product(s) : HEMO-CAR-T

                            Therapeutic Area : Oncology

                            Study Phase : IND Enabling

                            Sponsor : Not Applicable

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

                            DEALS_DEV arrow-down

                            Hemogenyx Pharmaceuticals PLC Announces CDX Development Update

                            Details : HEMO-CAR-T cell therapy is developed using Hemogenyx’s proprietary humanized monoclonal antibody. It is being evaluated in preclinical studies for the treatment of r/r acute myeloid leukemia.

                            Brand Name : HEMO-CAR-T

                            Molecule Type : Cell and Gene therapy

                            Upfront Cash : Not Applicable

                            September 02, 2024

                            Lead Product(s) : HEMO-CAR-T

                            Therapeutic Area : Oncology

                            Highest Development Status : IND Enabling

                            Sponsor : Not Applicable

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

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                            03

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                            Lead Product(s) : HEMO-CAR-T

                            Therapeutic Area : Oncology

                            Study Phase : IND Enabling

                            Sponsor : Not Applicable

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

                            DEALS_DEV arrow-down

                            Hemogenyx Pharmaceuticals PLC Announces Submission of Complete Response to Clinical Hold

                            Details : HEMO-CAR-T cell therapy is developed using Hemogenyx’s proprietary humanised monoclonal antibody. It is being evaluated in preclinical studies for the treatment of acute myeloid leukemia.

                            Brand Name : HEMO-CAR-T

                            Molecule Type : Cell and Gene therapy

                            Upfront Cash : Not Applicable

                            January 16, 2024

                            Lead Product(s) : HEMO-CAR-T

                            Therapeutic Area : Oncology

                            Highest Development Status : IND Enabling

                            Sponsor : Not Applicable

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

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                            04

                            Hemogenyx Pharmaceuticals

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                            Lead Product(s) : Human Macrophage-based Therapy

                            Therapeutic Area : Oncology

                            Study Phase : Discovery Platform

                            Sponsor : Not Applicable

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

                            DEALS_DEV arrow-down

                            Hemogenyx Pharmaceuticals PLC Announces CBR Expanded to Treatment of Cancer

                            Details : Human macrophages, a type of immune cells, programmed with a purpose designed CBR, were able to eliminate Non-Hodgkin Lymphoma derived cells with high efficiency in vitro.

                            Brand Name : Undisclosed

                            Molecule Type : Cell and Gene therapy

                            Upfront Cash : Not Applicable

                            November 27, 2023

                            Lead Product(s) : Human Macrophage-based Therapy

                            Therapeutic Area : Oncology

                            Highest Development Status : Discovery Platform

                            Sponsor : Not Applicable

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

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                            05

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                            Lead Product(s) : Undisclosed

                            Therapeutic Area : Oncology

                            Study Phase : Preclinical

                            Sponsor : Prevail InfoWorks

                            Deal Size : Undisclosed

                            Deal Type : Agreement

                            DEALS_DEV arrow-down

                            Hemogenyx Pharmaceuticals PLC Announces Strategic Investment from Prevail Partners, LLC

                            Details : Under the terms of the MSTA, InfoWorks is to provide clinical services and technologies for the Company's upcoming Phase I study of its anti-FLT3 chimeric antigen receptor-redirected T cells (CAR-T cells) in subjects with relapsed/refractory acute myeloi...

                            Brand Name : Undisclosed

                            Molecule Type : Cell and Gene therapy

                            Upfront Cash : Undisclosed

                            September 18, 2023

                            Lead Product(s) : Undisclosed

                            Therapeutic Area : Oncology

                            Highest Development Status : Preclinical

                            Sponsor : Prevail InfoWorks

                            Deal Size : Undisclosed

                            Deal Type : Agreement

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                            06

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                            Lead Product(s) : HEMO-CAR-T

                            Therapeutic Area : Oncology

                            Study Phase : IND Enabling

                            Sponsor : Not Applicable

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

                            DEALS_DEV arrow-down

                            Hemogenyx Pharmaceuticals PLC Announces Full FDA Review for HEMO-CAR-T IND

                            Details : HEMO-CAR-T is made using Hemogenyx’s proprietary humanised monoclonal antibody against a target on the surface of AML cells and potential treatment of Acute Myeloid Leukemia.

                            Brand Name : HEMO-CAR-T

                            Molecule Type : Cell and Gene therapy

                            Upfront Cash : Not Applicable

                            July 10, 2023

                            Lead Product(s) : HEMO-CAR-T

                            Therapeutic Area : Oncology

                            Highest Development Status : IND Enabling

                            Sponsor : Not Applicable

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

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                            07

                            Hemogenyx Pharmaceuticals

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                            Lead Product(s) : HEMO-CAR-T

                            Therapeutic Area : Oncology

                            Study Phase : IND Enabling

                            Sponsor : Not Applicable

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

                            DEALS_DEV arrow-down

                            Hemogenyx Pharmaceuticals PLC Announces Submission of IND for HEMO-CAR-T

                            Details : HEMO-CAR-T is being clinically evaluated for treating acute myeloid leukemia (AML). CAR-T therapy is a treatment in which a patient’s own T-cells, a type of immune cell, are modified to recognize and kill the patient’s cancer cells.

                            Brand Name : HEMO-CAR-T

                            Molecule Type : Cell and Gene therapy

                            Upfront Cash : Not Applicable

                            May 09, 2023

                            Lead Product(s) : HEMO-CAR-T

                            Therapeutic Area : Oncology

                            Highest Development Status : IND Enabling

                            Sponsor : Not Applicable

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

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                            08

                            Hemogenyx Pharmaceuticals

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                            Lead Product(s) : CDX bi-specific antibodies

                            Therapeutic Area : Oncology

                            Study Phase : Preclinical

                            Sponsor : KBI Biopharma

                            Deal Size : Undisclosed

                            Deal Type : Agreement

                            DEALS_DEV arrow-down

                            Hemogenyx Pharmaceuticals and Selexis SA Will Advance Hemogenyx’s Acute Myeloid Leukemia (AML) CDX Bispecifi...

                            Details : Under the agreement, Hemogenyx will leverage Selexis’ proprietary SUREtechnology Platform™, a suite of cell line development tools and technologies that significantly reduces the time, effort, and costs associated with developing high-performance mam...

                            Brand Name : Undisclosed

                            Molecule Type : Large molecule

                            Upfront Cash : Undisclosed

                            January 12, 2022

                            Lead Product(s) : CDX bi-specific antibodies

                            Therapeutic Area : Oncology

                            Highest Development Status : Preclinical

                            Sponsor : KBI Biopharma

                            Deal Size : Undisclosed

                            Deal Type : Agreement

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                            09

                            Hemogenyx Pharmaceuticals

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                            Lead Product(s) : CDX bi-specific Antibody

                            Therapeutic Area : Oncology

                            Study Phase : Preclinical

                            Recipient : Eli Lilly

                            Deal Size : $1.2 million

                            Deal Type : Licensing Agreement

                            DEALS_DEV arrow-down

                            Hemogenyx Pharmaceuticals Announces CDX Licence Agreement

                            Details : Under this Agreement, Lilly grants the Company an exclusive worldwide licence to certain intellectual property developed by Lilly related to a CDX bispecific antibody for all uses, including the treatment of acute myeloid leukemia and other blood cancers...

                            Brand Name : CDX bi-specific Antibody

                            Molecule Type : Large molecule

                            Upfront Cash : $0.2 million

                            October 13, 2021

                            Lead Product(s) : CDX bi-specific Antibody

                            Therapeutic Area : Oncology

                            Highest Development Status : Preclinical

                            Recipient : Eli Lilly

                            Deal Size : $1.2 million

                            Deal Type : Licensing Agreement

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                            10

                            Hemogenyx Pharmaceuticals

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                            Lead Product(s) : CAR-T therapy

                            Therapeutic Area : Oncology

                            Study Phase : Undisclosed

                            Recipient : University of Pennsylvania

                            Deal Size : Undisclosed

                            Deal Type : Agreement

                            DEALS_DEV arrow-down

                            Hemogenyx Pharmaceuticals PLC Announces CAR-T Agreement with University of Pennsylvania

                            Details : Agreement focused on advancing Chimeric Antigen Receptor T-cells ("HEMO-CAR-T") developed by Hemogenyx toward clinical trials and is envisaged as the first step of a larger program aimed at achieving clinical proof of concept for HEMO-CAR-T to treat AML.

                            Brand Name : HEMO-CAR-T

                            Molecule Type : Cell and Gene therapy

                            Upfront Cash : Undisclosed

                            August 11, 2020

                            Lead Product(s) : CAR-T therapy

                            Therapeutic Area : Oncology

                            Highest Development Status : Undisclosed

                            Recipient : University of Pennsylvania

                            Deal Size : Undisclosed

                            Deal Type : Agreement

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