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    [{"orgOrder":0,"company":"Heron Therapeutics","sponsor":"Not Applicable","pharmaFlowCategory":"DU","therapeuticArea":"Neurology","country":"","productType":"Small molecule","year":"2020","type":"Not Applicable","leadProduct":"Bupivacaine","moa":"Sodium channel","graph1":"Neurology","graph2":"Approved","graph3":"Heron Therapeutics","amount2":0,"highestDevelopmentShortName":"Approved","therapeuticAreaShortName":"Neurology","amount2New":0,"dosageForm":"Extended Release Solution","sponsorNew":"Heron Therapeutics \/ Not Applicable","highestDevelopmentStatusID":"12","companyTruncated":"Heron Therapeutics \/ Not Applicable"},{"orgOrder":0,"company":"Heron Therapeutics","sponsor":"Not Applicable","pharmaFlowCategory":"DU","therapeuticArea":"Orthopedics\/Orthopedic Surgery","country":"","productType":"Small molecule","year":"2020","type":"Not Applicable","leadProduct":"Bupivacaine","moa":"Sodium channel protein type IV alpha subunit","graph1":"Orthopedics\/Orthopedic 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                            01

                            Heron Therapeutics

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                            Lead Product(s) : Bupivacaine,Meloxicam

                            Therapeutic Area : Neurology

                            Study Phase : Approved

                            Sponsor : Mayo Clinic

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

                            DEALS_DEV arrow-down

                            FDA Approves ZYNRELEF® Vial Access Needle by Heron Therapeutics

                            Details : Zynrelef (bupivacaine, meloxicam) is an investigational local anesthetic given periarticularly as an extended-release solution for postoperative pain.

                            Brand Name : Zynrelef

                            Molecule Type : Small molecule

                            Upfront Cash : Not Applicable

                            September 25, 2024

                            Lead Product(s) : Bupivacaine,Meloxicam

                            Therapeutic Area : Neurology

                            Highest Development Status : Approved

                            Sponsor : Mayo Clinic

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

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                            02

                            Heron Therapeutics

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                            Lead Product(s) : Bupivacaine,Meloxicam

                            Therapeutic Area : Neurology

                            Study Phase : Phase III

                            Sponsor : Mayo Clinic

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

                            DEALS_DEV arrow-down

                            Heron Therapeutics Accepts Prior Approval Supplement for ZYNRELEF® Vial Access Needle

                            Details : Zynrelef (bupivacaine, meloxicam) is an investigational local anesthetic given periarticularly as an extended-release solution for postoperative pain. The FDA has set a PDUFA date of 23 Sep 2024.

                            Brand Name : Zynrelef

                            Molecule Type : Small molecule

                            Upfront Cash : Not Applicable

                            July 02, 2024

                            Lead Product(s) : Bupivacaine,Meloxicam

                            Therapeutic Area : Neurology

                            Highest Development Status : Phase III

                            Sponsor : Mayo Clinic

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

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                            03

                            Heron Therapeutics

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                            Lead Product(s) : Bupivacaine,Meloxicam

                            Therapeutic Area : Neurology

                            Study Phase : Phase III

                            Sponsor : Not Applicable

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

                            DEALS_DEV arrow-down

                            Heron Submits ZYNRELEF® Vial Access Needle for FDA Approval

                            Details : Company submmitted Prior Approval Supplement to the FDA for ZYNRELEF® (bupivacaine and meloxicam) extended-release solution Vial Access Needle kit.

                            Brand Name : Zynrelef

                            Molecule Type : Small molecule

                            Upfront Cash : Not Applicable

                            May 30, 2024

                            Lead Product(s) : Bupivacaine,Meloxicam

                            Therapeutic Area : Neurology

                            Highest Development Status : Phase III

                            Sponsor : Not Applicable

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

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                            04

                            Heron Therapeutics

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                            Heron Therapeutics

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                            Lead Product(s) : Bupivacaine,Meloxicam

                            Therapeutic Area : Neurology

                            Study Phase : Approved

                            Recipient : CrossLink Life Sciences

                            Deal Size : Undisclosed

                            Deal Type : Partnership

                            DEALS_DEV arrow-down

                            Heron Partners With CrossLink Life Sciences To Expand Promotional Effort For ZYNRELEF®

                            Details : The partnership aims to expand the sales network supporting Zynrelef (bupivacaine and meloxicam) extended-release solution, the first and only dual-acting local anesthetic, for post-operative pain.

                            Brand Name : Zynrelef

                            Molecule Type : Small molecule

                            Upfront Cash : Undisclosed

                            January 07, 2024

                            Lead Product(s) : Bupivacaine,Meloxicam

                            Therapeutic Area : Neurology

                            Highest Development Status : Approved

                            Recipient : CrossLink Life Sciences

                            Deal Size : Undisclosed

                            Deal Type : Partnership

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                            05

                            Heron Therapeutics

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                            Heron Therapeutics

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                            Lead Product(s) : Bupivacaine,Meloxicam

                            Therapeutic Area : Neurology

                            Study Phase : Approved

                            Sponsor : Not Applicable

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

                            DEALS_DEV arrow-down

                            Heron Therapeutics Announces Filing of an Efficacy Supplement for ZYNRELEF® and Provision in Newly Passed Con...

                            Details : ZYNRELEF is the first and only dual-acting local anesthetic that delivers a fixed-dose combination of the local anesthetic bupivacaine and a low dose of nonsteroidal anti-inflammatory drug meloxicam.

                            Brand Name : Zynrelef

                            Molecule Type : Small molecule

                            Upfront Cash : Not Applicable

                            December 29, 2022

                            Lead Product(s) : Bupivacaine,Meloxicam

                            Therapeutic Area : Neurology

                            Highest Development Status : Approved

                            Sponsor : Not Applicable

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

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                            06

                            Heron Therapeutics

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                            Lead Product(s) : Aprepitant

                            Therapeutic Area : Gastroenterology

                            Study Phase : Approved

                            Sponsor : Not Applicable

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

                            DEALS_DEV arrow-down

                            Heron Therapeutics Announces U.S. FDA Approval of APONVIE™ (HTX-019) for the Prevention of Postoperative Nau...

                            Details : Administered via a single 30-second IV injection, APONVIE(aprepitant) reaches drug levels associated with ≥97% receptor occupancy in the brain within five minutes and maintains therapeutic plasma concentrations for at least 48 hours.

                            Brand Name : Aponvie

                            Molecule Type : Small molecule

                            Upfront Cash : Not Applicable

                            September 16, 2022

                            Lead Product(s) : Aprepitant

                            Therapeutic Area : Gastroenterology

                            Highest Development Status : Approved

                            Sponsor : Not Applicable

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

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                            07

                            Heron Therapeutics

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                            Heron Therapeutics

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                            Lead Product(s) : Bupivacaine,Meloxicam

                            Therapeutic Area : Neurology

                            Study Phase : Approved

                            Sponsor : Not Applicable

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

                            DEALS_DEV arrow-down

                            Heron Therapeutics Announces Publication Showing ZYNRELEF® as the Foundation of a Perioperative Non-Opioid Mu...

                            Details : ZYNRELEF (bupivacaine) is first and only therapy for pain management to be rigorously tested demonstrated superiority to bupivacaine solution, and sustained postoperative pain relief for up to 72 hours and decreased need for opioids, with more patients o...

                            Brand Name : Zynrelef

                            Molecule Type : Small molecule

                            Upfront Cash : Not Applicable

                            June 14, 2022

                            Lead Product(s) : Bupivacaine,Meloxicam

                            Therapeutic Area : Neurology

                            Highest Development Status : Approved

                            Sponsor : Not Applicable

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

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                            08

                            Heron Therapeutics

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                            Lead Product(s) : Bupivacaine,Meloxicam

                            Therapeutic Area : Neurology

                            Study Phase : Approved

                            Sponsor : Not Applicable

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

                            DEALS_DEV arrow-down

                            Heron Therapeutics Presents ZYNRELEF® Data at the Society for Obstetric Anesthesia and Perinatology 54th Annu...

                            Details : New interim data from Phase 2 study suggests ZYNRELEF (bupivacaine) was well-tolerated and may effectively manage postpartum pain and minimize postoperative opioid use in women undergoing Caesarean sections.

                            Brand Name : Zynrelef

                            Molecule Type : Small molecule

                            Upfront Cash : Not Applicable

                            May 16, 2022

                            Lead Product(s) : Bupivacaine,Meloxicam

                            Therapeutic Area : Neurology

                            Highest Development Status : Approved

                            Sponsor : Not Applicable

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

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                            09

                            Heron Therapeutics

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                            Heron Therapeutics

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                            Lead Product(s) : Bupivacaine,Meloxicam

                            Therapeutic Area : Neurology

                            Study Phase : Approved

                            Sponsor : Not Applicable

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

                            DEALS_DEV arrow-down

                            Heron Therapeutics Announces Approval of ZYNRELEF® by Health Canada for the Management of Postoperative Pain

                            Details : ZYNRELEF is first and only therapy of dual-acting fixed-dose combination of local anesthetic bupivacaine and a low dose of meloxicam, for postoperative pain management to be rigorously tested in Phase 3 studies and demonstrate superiority to bupivacaine ...

                            Brand Name : Zynrelef

                            Molecule Type : Small molecule

                            Upfront Cash : Not Applicable

                            March 17, 2022

                            Lead Product(s) : Bupivacaine,Meloxicam

                            Therapeutic Area : Neurology

                            Highest Development Status : Approved

                            Sponsor : Not Applicable

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

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                            10

                            Heron Therapeutics

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                            Lead Product(s) : Bupivacaine,Meloxicam

                            Therapeutic Area : Neurology

                            Study Phase : Approved

                            Sponsor : Not Applicable

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

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                            Heron Therapeutics Announces Publication of Results from HOPE Trial for ZYNRELEF™

                            Details : ZYNRELEF is an extended-release solution of bupivacaine and meloxicam that is indicated in adults for soft tissue or periarticular instillation to produce postsurgical analgesia for up to 72 hours after bunionectomy, open inguinal herniorrhaphy, and tota...

                            Brand Name : Zynrelef

                            Molecule Type : Small molecule

                            Upfront Cash : Not Applicable

                            July 28, 2021

                            Lead Product(s) : Bupivacaine,Meloxicam

                            Therapeutic Area : Neurology

                            Highest Development Status : Approved

                            Sponsor : Not Applicable

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

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