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    [{"orgOrder":0,"company":"HiberCell","sponsor":"Labcorp Drug Development","pharmaFlowCategory":"DU","therapeuticArea":"Oncology","country":"U.S.A","productType":"Small molecule","year":"2021","type":"Not Applicable","leadProduct":"HC-5404","moa":"","graph1":"Oncology","graph2":"Phase I","graph3":"HiberCell","amount2":0,"highestDevelopmentShortName":"Ph I","therapeuticAreaShortName":"Oncology","amount2New":0,"dosageForm":"Capsule","sponsorNew":"HiberCell \/ Covance","highestDevelopmentStatusID":"6","companyTruncated":"HiberCell \/ Covance"},{"orgOrder":0,"company":"HiberCell","sponsor":"Not Applicable","pharmaFlowCategory":"DU","therapeuticArea":"Oncology","country":"U.S.A","productType":"Small molecule","year":"2021","type":"Not Applicable","leadProduct":"HC-5404","moa":"","graph1":"Oncology","graph2":"Phase I","graph3":"HiberCell","amount2":0,"highestDevelopmentShortName":"Ph I","therapeuticAreaShortName":"Oncology","amount2New":0,"dosageForm":"Capsule","sponsorNew":"HiberCell \/ 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\/ Not Applicable","highestDevelopmentStatusID":"6","companyTruncated":"HiberCell \/ Not Applicable"},{"orgOrder":0,"company":"HiberCell","sponsor":"Not Applicable","pharmaFlowCategory":"DU","therapeuticArea":"Oncology","country":"U.S.A","productType":"Small molecule","year":"2024","type":"Not Applicable","leadProduct":"HC-7366","moa":"","graph1":"Oncology","graph2":"Phase I","graph3":"HiberCell","amount2":0,"highestDevelopmentShortName":"Ph I","therapeuticAreaShortName":"Oncology","amount2New":0,"dosageForm":"Immediate Release Capsule","sponsorNew":"HiberCell \/ Not Applicable","highestDevelopmentStatusID":"6","companyTruncated":"HiberCell \/ Not Applicable"},{"orgOrder":0,"company":"HiberCell","sponsor":"Not Applicable","pharmaFlowCategory":"DU","therapeuticArea":"Oncology","country":"U.S.A","productType":"Small molecule","year":"2024","type":"Not Applicable","leadProduct":"HC-7366","moa":"","graph1":"Oncology","graph2":"Phase 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    Find Clinical Drug Pipeline Developments & Deals by HiberCell

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                            01

                            HiberCell

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                            HiberCell

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                            Lead Product(s) : HC-7366,Azacitidine,Venetoclax

                            Therapeutic Area : Oncology

                            Study Phase : Phase I

                            Sponsor : Not Applicable

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

                            DEALS_DEV arrow-down

                            HiberCell Gets FDA Fast Track for HC-7366 in Relapsed AML

                            Details : HC-7366 is a first-in-class, first-in-human, selective, potent, small molecule activator of the general control nonderepressible 2 (GCN2) kinase. It is being evaluated for the treatment of r/r AML.

                            Brand Name : HC-7366

                            Molecule Type : Small molecule

                            Upfront Cash : Not Applicable

                            October 23, 2024

                            Lead Product(s) : HC-7366,Azacitidine,Venetoclax

                            Therapeutic Area : Oncology

                            Highest Development Status : Phase I

                            Sponsor : Not Applicable

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

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                            02

                            HiberCell

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                            Lead Product(s) : HC-7366,Azacitidine,Venetoclax

                            Therapeutic Area : Oncology

                            Study Phase : Phase I

                            Sponsor : Not Applicable

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

                            DEALS_DEV arrow-down

                            HiberCell Doses First Patient in Phase 1b Trial of HC-7366 in AML Treatment

                            Details : HC-7366 is a first-in-human, small molecule activator of the GCN2 kinase, which is being evaluated in combination with venetoclax and azacitidine in AML patients.

                            Brand Name : HC-7366

                            Molecule Type : Small molecule

                            Upfront Cash : Not Applicable

                            May 28, 2024

                            Lead Product(s) : HC-7366,Azacitidine,Venetoclax

                            Therapeutic Area : Oncology

                            Highest Development Status : Phase I

                            Sponsor : Not Applicable

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

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                            03

                            HiberCell

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                            Lead Product(s) : HC-7366,Belzutifan

                            Therapeutic Area : Oncology

                            Study Phase : Phase I

                            Sponsor : Not Applicable

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

                            DEALS_DEV arrow-down

                            HiberCell Doses First Patient in Merck Collaboration for Advanced ccRCC

                            Details : HC-7366, a selective activator of general control nonderepressible 2 kinases, is under investigation with Welireg for clear cell renal cell carcinoma treatment.

                            Brand Name : HC-7366

                            Molecule Type : Small molecule

                            Upfront Cash : Not Applicable

                            May 01, 2024

                            Lead Product(s) : HC-7366,Belzutifan

                            Therapeutic Area : Oncology

                            Highest Development Status : Phase I

                            Sponsor : Not Applicable

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

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                            04

                            HiberCell

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                            Lead Product(s) : HC-7366,Belzutifan

                            Therapeutic Area : Oncology

                            Study Phase : Preclinical

                            Sponsor : Merck & Co

                            Deal Size : Undisclosed

                            Deal Type : Collaboration

                            DEALS_DEV arrow-down

                            HiberCell, Inc. Announces Clinical Collaboration with Merck to Evaluate HC-7366, an Activator of ISR Kinase GC...

                            Details : The collaboration aims to evaluate HiberCell's HC-7366, a selective activator of the general control nonderepressible 2 kinases in combination with Welireg (belzutifan), Merck’s oral HIF-2α inhibitor for the treatment of clear cell renal cell carcinom...

                            Brand Name : HC-7366

                            Molecule Type : Small molecule

                            Upfront Cash : Undisclosed

                            December 05, 2023

                            Lead Product(s) : HC-7366,Belzutifan

                            Therapeutic Area : Oncology

                            Highest Development Status : Preclinical

                            Sponsor : Merck & Co

                            Deal Size : Undisclosed

                            Deal Type : Collaboration

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                            05

                            HiberCell

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                            HiberCell

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                            Lead Product(s) : HC-5404

                            Therapeutic Area : Oncology

                            Study Phase : Phase I

                            Sponsor : Not Applicable

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

                            DEALS_DEV arrow-down

                            HiberCell Announces Successful Completion and Interim Results of Phase 1 Study of Novel PERK Inhibitor, HC-540...

                            Details : HC-5404 is a first-in-class, first-in-human selective and potent PKR-like endoplasmic reticulum kinase (PERK) inhibitor. Itis being evaluated in phase 1 clinical trials for the treatment of solid tumors.

                            Brand Name : HC-5404

                            Molecule Type : Small molecule

                            Upfront Cash : Not Applicable

                            November 27, 2023

                            Lead Product(s) : HC-5404

                            Therapeutic Area : Oncology

                            Highest Development Status : Phase I

                            Sponsor : Not Applicable

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

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                            06

                            HiberCell

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                            HiberCell

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                            Lead Product(s) : Odetiglucan,CDX-1140

                            Therapeutic Area : Oncology

                            Study Phase : Phase I

                            Sponsor : Celldex Therapeutics

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

                            DEALS_DEV arrow-down

                            HiberCell Doses First Patient in Phase 1b Study Exploring Novel Combination of Odetiglucan and CD40 Agonistic ...

                            Details : Imprime PGG (odetiglucan) is a pathogen-associated molecular pattern which is designed to enhance innate immune functions, including cytotoxic effector mechanisms, to reverse immunosuppression and facilitate cross-talk with the adaptive immune system.

                            Brand Name : Imprime PGG

                            Molecule Type : Large molecule

                            Upfront Cash : Not Applicable

                            May 22, 2023

                            Lead Product(s) : Odetiglucan,CDX-1140

                            Therapeutic Area : Oncology

                            Highest Development Status : Phase I

                            Sponsor : Celldex Therapeutics

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

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                            07

                            HiberCell

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                            HiberCell

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                            Lead Product(s) : HC-7366

                            Therapeutic Area : Oncology

                            Study Phase : Phase I

                            Sponsor : Not Applicable

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

                            DEALS_DEV arrow-down

                            HiberCell Maps Forward Path for Novel GCN2 Activator, HC-7366 in Acute Myeloid Leukemia (AML)

                            Details : HC-7366, a first-in-class, first-in-human GCN2 activator. In preclinical studies, HC-7366 was observed to have robust anti-tumor and immunomodulatory activity in a variety of models of solid tumors and hematological malignancies.

                            Brand Name : HC-7366

                            Molecule Type : Large molecule

                            Upfront Cash : Not Applicable

                            February 22, 2023

                            Lead Product(s) : HC-7366

                            Therapeutic Area : Oncology

                            Highest Development Status : Phase I

                            Sponsor : Not Applicable

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

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                            08

                            HiberCell

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                            HiberCell

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                            Lead Product(s) : HC-7366

                            Therapeutic Area : Oncology

                            Study Phase : Phase I

                            Sponsor : Not Applicable

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

                            DEALS_DEV arrow-down

                            HiberCell to Present Preclinical Data from Novel GCN2 Activator and PERK Inhibitor Programs at The Society for...

                            Details : The posters will present the immunomodulatory mechanisms of HC-7366, a differentiated selective, orally bioavailable activator of GCN2 (general controlled nonderepressible 2). HiberCell is currently conducting Phase 1 clinical trials in solid tumors for ...

                            Brand Name : HC-7366

                            Molecule Type : Large molecule

                            Upfront Cash : Not Applicable

                            November 02, 2022

                            Lead Product(s) : HC-7366

                            Therapeutic Area : Oncology

                            Highest Development Status : Phase I

                            Sponsor : Not Applicable

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

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                            09

                            HiberCell

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                            HiberCell

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                            Lead Product(s) : Odetiglucan,Pembrolizumab

                            Therapeutic Area : Oncology

                            Study Phase : Phase II

                            Sponsor : Not Applicable

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

                            DEALS_DEV arrow-down

                            HiberCell to Present Posters on Novel Candidates Odetiglucan and HC-7366 at the 2022 Annual American Society o...

                            Details : Imprime PGG (odetiglucan) is a pathogen-associated molecular pattern which is designed to enhance innate immune functions, including cytotoxic effector mechanisms, to reverse immunosuppression and facilitate cross-talk with the adaptive immune system.

                            Brand Name : Imprime PGG

                            Molecule Type : Large molecule

                            Upfront Cash : Not Applicable

                            May 24, 2022

                            Lead Product(s) : Odetiglucan,Pembrolizumab

                            Therapeutic Area : Oncology

                            Highest Development Status : Phase II

                            Sponsor : Not Applicable

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

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                            10

                            HiberCell

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                            Lead Product(s) : Odetiglucan,Pembrolizumab

                            Therapeutic Area : Oncology

                            Study Phase : Phase II

                            Sponsor : Not Applicable

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

                            DEALS_DEV arrow-down

                            HiberCell Announces First Patients Dosed in Phase 2 Clinical Trial of Odetiglucan in Combination with KEYTRUDA...

                            Details : Odetiglucan, a novel intravenously administered investigational innate and adaptive immune modulator, has previously been investigated in combination with pembrolizumab in immune checkpoint inhibitor-naive metastatic triple negative breast cancer patient...

                            Brand Name : Imprime PGG

                            Molecule Type : Large molecule

                            Upfront Cash : Not Applicable

                            April 28, 2022

                            Lead Product(s) : Odetiglucan,Pembrolizumab

                            Therapeutic Area : Oncology

                            Highest Development Status : Phase II

                            Sponsor : Not Applicable

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

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