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    [{"orgOrder":0,"company":"Polaryx Therapeutics","sponsor":"Inapplicable","pharmaFlowCategory":"DU","therapeuticArea":"Genetic Disease","country":"U.S.A","productType":"Other Small Molecule","year":"2021","type":"Inapplicable","leadProduct":"Gemfibrozil","moa":"PPA-gamma receptor","graph1":"Genetic Disease","graph2":"IND Enabling","graph3":"Polaryx Therapeutics","amount2":0,"highestDevelopmentShortName":"IND","therapeuticAreaShortName":"Genetic Disease","amount2New":0,"dosageForm":"Oral Solution","sponsorNew":"Polaryx Therapeutics \/ Inapplicable","highestDevelopmentStatusID":"5","companyTruncated":"Polaryx Therapeutics \/ Inapplicable"},{"orgOrder":0,"company":"Polaryx Therapeutics","sponsor":"Inapplicable","pharmaFlowCategory":"DU","therapeuticArea":"Rare Diseases and Disorders","country":"U.S.A","productType":"Other Small Molecule","year":"2020","type":"Inapplicable","leadProduct":"Gemfibrozil","moa":"PPA-gamma receptor","graph1":"Rare Diseases and Disorders","graph2":"IND Enabling","graph3":"Polaryx Therapeutics","amount2":0,"highestDevelopmentShortName":"IND","therapeuticAreaShortName":"Rare Diseases","amount2New":0,"dosageForm":"Undisclosed","sponsorNew":"Polaryx Therapeutics \/ Inapplicable","highestDevelopmentStatusID":"5","companyTruncated":"Polaryx Therapeutics \/ Inapplicable"},{"orgOrder":0,"company":"Polaryx Therapeutics","sponsor":"Inapplicable","pharmaFlowCategory":"DU","therapeuticArea":"Rare Diseases and Disorders","country":"U.S.A","productType":"Other Small Molecule","year":"2020","type":"Inapplicable","leadProduct":"Gemfibrozil","moa":"PPA-gamma receptor","graph1":"Rare Diseases and Disorders","graph2":"IND Enabling","graph3":"Polaryx Therapeutics","amount2":0,"highestDevelopmentShortName":"IND","therapeuticAreaShortName":"Rare Diseases","amount2New":0,"dosageForm":"Undisclosed","sponsorNew":"Polaryx Therapeutics \/ Inapplicable","highestDevelopmentStatusID":"5","companyTruncated":"Polaryx Therapeutics \/ Inapplicable"}]

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                            01

                            Polaryx Therapeutics

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                            MAGHREB PHARMA
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                            Polaryx Therapeutics

                            U.S.A arrow
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                            Lead Product(s) : Gemfibrozil

                            Therapeutic Area : Genetic Disease

                            Study Phase : IND Enabling

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

                            DEALS_DEV arrow-down

                            US FDA Grants Orphan Drug Designation to Polaryx Therapeutics’ PLX-200 to Treat GM2 Gangliosidoses

                            Details : PLX-200 is a repurposed drug that binds to the retinoid X receptor-α (RXRα), which binds to PPARα. PLX-200 also activates PPARα, which enhances production of transcription factor EB (TFEB).

                            Product Name : PLX-200

                            Product Type : Other Small Molecule

                            Upfront Cash : Inapplicable

                            August 30, 2021

                            Lead Product(s) : Gemfibrozil

                            Therapeutic Area : Genetic Disease

                            Highest Development Status : IND Enabling

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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                            02

                            Polaryx Therapeutics

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                            MAGHREB PHARMA
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                            Polaryx Therapeutics

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                            Lead Product(s) : Gemfibrozil

                            Therapeutic Area : Rare Diseases and Disorders

                            Study Phase : IND Enabling

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

                            DEALS_DEV arrow-down

                            Polaryx Therapeutics Receives IND Approval From the FDA to Study PLX-200

                            Details : Company has received an IND approval from the U.S.FDA to study PLX-200 treatment on Juvenile Neuronal Ceroid Lipofuscinosis (JNCL or CLN3) patients.

                            Product Name : PLX-200

                            Product Type : Other Small Molecule

                            Upfront Cash : Inapplicable

                            August 04, 2020

                            Lead Product(s) : Gemfibrozil

                            Therapeutic Area : Rare Diseases and Disorders

                            Highest Development Status : IND Enabling

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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                            03

                            Polaryx Therapeutics

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                            Polaryx Therapeutics

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                            Lead Product(s) : Gemfibrozil

                            Therapeutic Area : Rare Diseases and Disorders

                            Study Phase : IND Enabling

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

                            DEALS_DEV arrow-down

                            Polaryx Therapeutics Receives IND Approval for PLX-200 From the FDA for the Treatment of Late Infantile Neuron...

                            Details : This IND approval will allow Polaryx Therapeutics to advance PLX-200 clinical studies for LINCL patients.

                            Product Name : PLX-200

                            Product Type : Other Small Molecule

                            Upfront Cash : Inapplicable

                            January 20, 2020

                            Lead Product(s) : Gemfibrozil

                            Therapeutic Area : Rare Diseases and Disorders

                            Highest Development Status : IND Enabling

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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