Year
DEALS // DEV.
Country
Therapeutic Area
Study Phase
Deal Type
Product Type
Dosage Form
Lead Product
Target
Lead Product(s) : HFB200301,Tislelizumab
Therapeutic Area : Oncology
Study Phase : Phase I
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Details : HFB200301, a first-in-class agonistic anti-TNFR2 monoclonal antibody, in combination with tislelizumab, an investigational anti-PD-1 immune checkpoint inhibitor, for the treatment of advanced solid tumor.
Brand Name : HFB200301
Molecule Type : Large molecule
Upfront Cash : Not Applicable
June 23, 2023
Lead Product(s) : HFB200301,Tislelizumab
Therapeutic Area : Oncology
Highest Development Status : Phase I
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Lead Product(s) : HFB200603,Tislelizumab
Therapeutic Area : Oncology
Study Phase : IND Enabling
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
HiFiBiO Therapeutics Receives FDA Clearance of IND Application for HFB200603
Details : HFB200603 is a single-digit nanomolar binder to human and cynomolgus BTLA, capable of blocking BTLA interaction with its ligand HVEM, inducing the production of inflammatory cytokines in the tumor microenvironment of different human tumor types.
Brand Name : HFB200603
Molecule Type : Large molecule
Upfront Cash : Not Applicable
January 06, 2023
Lead Product(s) : HFB200603,Tislelizumab
Therapeutic Area : Oncology
Highest Development Status : IND Enabling
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Lead Product(s) : HFB200603,Tislelizumab
Therapeutic Area : Oncology
Study Phase : Preclinical
Sponsor : Novartis Pharmaceuticals Corporation
Deal Size : Undisclosed
Deal Type : Agreement
Details : Under the terms of the agreement, HiFiBiO Therapeutics will maintain control of the HFB200603 program, including global R&D and commercial rights. Novartis has agreed to supply tislelizumab for use in combination with HFB200603.
Brand Name : HFB200603
Molecule Type : Large molecule
Upfront Cash : Undisclosed
November 18, 2022
Lead Product(s) : HFB200603,Tislelizumab
Therapeutic Area : Oncology
Highest Development Status : Preclinical
Sponsor : Novartis Pharmaceuticals Corporation
Deal Size : Undisclosed
Deal Type : Agreement
Lead Product(s) : HFB200301,Tislelizumab
Therapeutic Area : Oncology
Study Phase : Preclinical
Sponsor : Novartis Pharmaceuticals Corporation
Deal Size : Undisclosed
Deal Type : Agreement
Details : Under the terms of the agreement, HiFiBiO Therapeutics will maintain control of the HFB200301 program, including global R&D and commercial rights. Novartis has agreed to supply tislelizumab for use in combination with HFB200301.
Brand Name : HFB200301
Molecule Type : Large molecule
Upfront Cash : Undisclosed
August 15, 2022
Lead Product(s) : HFB200301,Tislelizumab
Therapeutic Area : Oncology
Highest Development Status : Preclinical
Sponsor : Novartis Pharmaceuticals Corporation
Deal Size : Undisclosed
Deal Type : Agreement
Lead Product(s) : HFB200301
Therapeutic Area : Oncology
Study Phase : IND Enabling
Sponsor : Mirae Asset Financial Group
Deal Size : $75.0 million
Deal Type : Series D Financing
Details : HiFiBiO Therapeutics will use the proceeds from the financing to advance two lead antibody oncology assets into Phase I clinical trials - HFB200301, a novel anti-TNFR2 antibody and HFB301001, a differentiated second generation anti-OX-40 antibody.
Brand Name : HFB200301
Molecule Type : Large molecule
Upfront Cash : Undisclosed
June 14, 2021
Lead Product(s) : HFB200301
Therapeutic Area : Oncology
Highest Development Status : IND Enabling
Sponsor : Mirae Asset Financial Group
Deal Size : $75.0 million
Deal Type : Series D Financing
Lead Product(s) : HFB30132A
Therapeutic Area : Infections and Infectious Diseases
Study Phase : Phase I
Recipient : Pharmsynthez
Deal Size : Undisclosed
Deal Type : Partnership
HiFiBiO, Pharmsynthez and IBCh Sign Covid-19 Antibody Development Deal
Details : The partnership aims to advance HFB30132A, a SARS-CoV-2 neutralizing antibody for the treatment of COVID-19, through clinical development and commercial sale in Russia, pending approval from the Ministry of Health of the Russian Federation.
Brand Name : HFB30132A
Molecule Type : Large molecule
Upfront Cash : Undisclosed
November 23, 2020
Lead Product(s) : HFB30132A
Therapeutic Area : Infections and Infectious Diseases
Highest Development Status : Phase I
Recipient : Pharmsynthez
Deal Size : Undisclosed
Deal Type : Partnership
Lead Product(s) : HFB30132A
Therapeutic Area : Infections and Infectious Diseases
Study Phase : IND Enabling
Recipient : ABL Bio
Deal Size : Undisclosed
Deal Type : Partnership
Details : Partnership with ABL Bio supports HiFiBiO Therapeutics' rapid clinical advancement of its SARS-CoV-2 neutralizing antibody, HFB30132A, for the treatment of COVID-19 patients.
Brand Name : HFB30132A
Molecule Type : Large molecule
Upfront Cash : Undisclosed
September 14, 2020
Lead Product(s) : HFB30132A
Therapeutic Area : Infections and Infectious Diseases
Highest Development Status : IND Enabling
Recipient : ABL Bio
Deal Size : Undisclosed
Deal Type : Partnership
Lead Product(s) : Anti-AML specific antibodies
Therapeutic Area : Oncology
Study Phase : Discovery
Sponsor : Kite Pharma
Deal Size : Undisclosed
Deal Type : Collaboration
Details : Through this collaboration, HiFiBiO will use its proprietary technology platforms to identify novel AML targets and anti-AML specific antibodies for Kite’s use in cell therapies.
Brand Name : Undisclosed
Molecule Type : Large molecule
Upfront Cash : Undisclosed
September 03, 2020
Lead Product(s) : Anti-AML specific antibodies
Therapeutic Area : Oncology
Highest Development Status : Discovery
Sponsor : Kite Pharma
Deal Size : Undisclosed
Deal Type : Collaboration
Lead Product(s) : HFB30132A
Therapeutic Area : Infections and Infectious Diseases
Study Phase : IND Enabling
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Details : The highly differentiated antibody, HFB30132A, has been rapidly identified, engineered, and evaluated in multiple preclinical studies. A Phase I single-IV administration ascending dose study will assess the safety, tolerability, and pharmacokinetics of H...
Brand Name : HFB30132A
Molecule Type : Large molecule
Upfront Cash : Not Applicable
August 26, 2020
Lead Product(s) : HFB30132A
Therapeutic Area : Infections and Infectious Diseases
Highest Development Status : IND Enabling
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Lead Product(s) : Mono & Bi-specific antibodies
Therapeutic Area : Infections and Infectious Diseases
Study Phase : Preclinical
Sponsor : Coronavirus Immunotherapy Consortium
Deal Size : Undisclosed
Deal Type : Collaboration
Details : Company leverages its unprecedented antibody drug discovery and development engine empowered by proprietary single-cell profiling technology to identify, engineer, and evaluate multiple neutralizing antibodies against SARS-CoV-2.
Brand Name : Undisclosed
Molecule Type : Large molecule
Upfront Cash : Undisclosed
August 17, 2020
Lead Product(s) : Mono & Bi-specific antibodies
Therapeutic Area : Infections and Infectious Diseases
Highest Development Status : Preclinical
Sponsor : Coronavirus Immunotherapy Consortium
Deal Size : Undisclosed
Deal Type : Collaboration
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