Year
DEALS // DEV.
Country
Therapeutic Area
Study Phase
Deal Type
Product Type
Dosage Form
Lead Product
Target
Lead Product(s) : Undisclosed
Therapeutic Area : Oncology
Study Phase : Discovery Platform
Sponsor : Bridge Biotherapeutics
Deal Size : Undisclosed
Deal Type : Collaboration
Bridge Biotherapeutics and HitGen Collaborate on Novel Cancer Therapeutics Program
Details : The collaboration builds on successful initial hit finding and identification work from HitGen's DNA-encoded library, aiming to further develop the novel hits as promising drug candidates for cancer.
Brand Name : Undisclosed
Molecule Type : Small molecule
Upfront Cash : Undisclosed
August 22, 2024
Lead Product(s) : Undisclosed
Therapeutic Area : Oncology
Highest Development Status : Discovery Platform
Sponsor : Bridge Biotherapeutics
Deal Size : Undisclosed
Deal Type : Collaboration
HitGen Announces Drug Discovery Research Agreement with ARase Therapeutics
Details : Under the agreement, HitGen will utilize its DNA-encoded library (DEL) technology platform, centered around the design, synthesis and screening of DELs, to identify novel inhibitors of ARase's validated oncology targets.
Brand Name : Undisclosed
Molecule Type : Small molecule
Upfront Cash : Undisclosed
May 18, 2023
Details : During the collaboration, multiple undisclosed targets were screened against HitGen’s proprietary over 1 trillion DNA-encoded libraries (DELs). The majority of the targets have resulted in confirmed hits, which have high potential for PROTAC developmen...
Brand Name : Undisclosed
Molecule Type : Small molecule
Upfront Cash : Undisclosed
April 06, 2022
Lead Product(s) : Undisclosed
Therapeutic Area : Neurology
Study Phase : Discovery
Sponsor : Mitsubishi Tanabe Pharma
Deal Size : Undisclosed
Deal Type : Collaboration
Details : During the three-year collaboration, multiple undisclosed targets (including undruggable targets) were screened against HitGen’s proprietary DNA encoded chemical libraries (DELs). The majority of the targets have resulted in confirmed novel potent hits...
Brand Name : Undisclosed
Molecule Type : Small molecule
Upfront Cash : Undisclosed
February 25, 2022
Lead Product(s) : Undisclosed
Therapeutic Area : Neurology
Highest Development Status : Discovery
Sponsor : Mitsubishi Tanabe Pharma
Deal Size : Undisclosed
Deal Type : Collaboration
Lead Product(s) : Undisclosed
Therapeutic Area : Oncology
Study Phase : Discovery Platform
Sponsor : UPPTHERA
Deal Size : Undisclosed
Deal Type : Collaboration
HitGen and UPPTHERA Enter Into Drug Discovery Research Collaboration
Details : HitGen has entered into a drug discovery research collaboration with UPPTHERA Inc. to identify small molecule Hits against previous known-to-be undruggable targets and novel E3 ligase. Identified compounds will be exclusively licensed to UPPTHERA for fur...
Brand Name : Undisclosed
Molecule Type : Small molecule
Upfront Cash : Undisclosed
February 28, 2021
Lead Product(s) : Undisclosed
Therapeutic Area : Oncology
Highest Development Status : Discovery Platform
Sponsor : UPPTHERA
Deal Size : Undisclosed
Deal Type : Collaboration
Lead Product(s) : Undisclosed
Therapeutic Area : Oncology
Study Phase : Discovery
Sponsor : Merck & Co
Deal Size : Undisclosed
Deal Type : Collaboration
Details : HitGen and Merck have expand their collaboration with a license to develop a novel class of drugs for an early target of high interest. HitGen will grant exclusive rights to Merck & Co., Inc Kenilworth, NJ USA to develop and commercialize the licensed c...
Brand Name : Undisclosed
Molecule Type : Small molecule
Upfront Cash : Undisclosed
December 21, 2020
Lead Product(s) : Undisclosed
Therapeutic Area : Oncology
Highest Development Status : Discovery
Sponsor : Merck & Co
Deal Size : Undisclosed
Deal Type : Collaboration
Lead Product(s) : HG030
Therapeutic Area : Oncology
Study Phase : Preclinical
Sponsor : Guangzhou Baiyunshan Pharmaceutical Holdings
Deal Size : Undisclosed
Deal Type : Licensing Agreement
Details : Baiyunshan will get exclusive rights to develop and market HG030 in mainland China, and will pay HitGen an upfront licensing fee and a series of milestones and royalty of sales as the product progresses through clinical trials and launches in the mainlan...
Brand Name : HG030
Molecule Type : Small molecule
Upfront Cash : $5.8 million
November 10, 2020
Lead Product(s) : HG030
Therapeutic Area : Oncology
Highest Development Status : Preclinical
Sponsor : Guangzhou Baiyunshan Pharmaceutical Holdings
Deal Size : Undisclosed
Deal Type : Licensing Agreement
Lead Product(s) : Undisclosed
Therapeutic Area : Dermatology
Study Phase : Discovery Platform
Sponsor : Almirall
Deal Size : Undisclosed
Deal Type : Collaboration
HitGen and Almirall Announce Achievement of Milestoneinn their Strategic Collaboration
Details : Multiple small molecule leads for an undisclosed target nominated by Almirall were the subject of this achievement. HitGen will grant exclusive rights to Almirall for further development and commercialization, and be eligible for preclinical and clinical...
Brand Name : Undisclosed
Molecule Type : Small molecule
Upfront Cash : Undisclosed
August 26, 2020
Lead Product(s) : Undisclosed
Therapeutic Area : Dermatology
Highest Development Status : Discovery Platform
Sponsor : Almirall
Deal Size : Undisclosed
Deal Type : Collaboration
Lead Product(s) : Undisclosed
Therapeutic Area : Immunology
Study Phase : Discovery
Sponsor : Morphic Therapeutic
Deal Size : Undisclosed
Deal Type : Collaboration
HitGen and Morphic Extend Drug Discovery Research Collaboration
Details : Under the terms of the extended agreement, HitGen will use its platform technology, based on the design, synthesis and interrogation by selection of DELs to discover ligands for targets of interest to Morphic.
Brand Name : Undisclosed
Molecule Type : Small molecule
Upfront Cash : Undisclosed
July 06, 2020
Lead Product(s) : Undisclosed
Therapeutic Area : Immunology
Highest Development Status : Discovery
Sponsor : Morphic Therapeutic
Deal Size : Undisclosed
Deal Type : Collaboration
Lead Product(s) : Undisclosed
Therapeutic Area : Infections and Infectious Diseases
Study Phase : Discovery
Sponsor : Evotec
Deal Size : Undisclosed
Deal Type : Collaboration
HitGen and Evotec SE Enter Into Drug Discovery Research Collaboration
Details : HitGen will apply its platform technology, based on the design, synthesis and screening of DNA-encoded libraries (DEL) to identify small molecule leads against targets of interest to Evotec SE in the field of anti-infectives.
Brand Name : Undisclosed
Molecule Type : Small molecule
Upfront Cash : Undisclosed
June 08, 2020
Lead Product(s) : Undisclosed
Therapeutic Area : Infections and Infectious Diseases
Highest Development Status : Discovery
Sponsor : Evotec
Deal Size : Undisclosed
Deal Type : Collaboration
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