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                          Therapeutic Area by Lead Product

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                          Top Deals by Deal Size (USD bn)

                          01

                          The Pharmacy Technology
                          Not Confirmed
                          The Pharmacy Technology
                          Not Confirmed

                          Details : HB-500 is an alternating, 2-vector novel arenaviral therapeutic vaccine which is under clinical development for the treatment of human immunodeficiency virus (HIV).

                          Brand Name : HB-500

                          Molecule Type : Vaccine

                          Upfront Cash : Not Applicable

                          July 01, 2024

                          Lead Product(s) : HB-500

                          Therapeutic Area : Infections and Infectious Diseases

                          Highest Development Status : Phase I

                          Sponsor : Gilead Sciences

                          Deal Size : Not Applicable

                          Deal Type : Not Applicable

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                          02

                          The Pharmacy Technology
                          Not Confirmed
                          The Pharmacy Technology
                          Not Confirmed

                          Details : HB-200, in combination with pembrolizumab, will undergo evaluation as a first-line treatment for patients with HPV16+ recurrent or metastatic oropharyngeal squamous cell carcinoma.

                          Brand Name : HB-200

                          Molecule Type : Vaccine

                          Upfront Cash : Not Applicable

                          April 25, 2024

                          Lead Product(s) : HB-200,Pembrolizumab

                          Therapeutic Area : Oncology

                          Highest Development Status : Phase II

                          Sponsor : Not Applicable

                          Deal Size : Not Applicable

                          Deal Type : Not Applicable

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                          03

                          The Pharmacy Technology
                          Not Confirmed
                          The Pharmacy Technology
                          Not Confirmed

                          Details : HB-700 is an arenaviral therapeutic vaccine targeting KRAS mutations in lung, colorectal, and pancreatic cancers.

                          Brand Name : HB-700

                          Molecule Type : Vaccine

                          Upfront Cash : Not Applicable

                          April 24, 2024

                          Lead Product(s) : HB-700

                          Therapeutic Area : Oncology

                          Highest Development Status : IND Enabling

                          Sponsor : Not Applicable

                          Deal Size : Not Applicable

                          Deal Type : Not Applicable

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                          04

                          The Pharmacy Technology
                          Not Confirmed
                          The Pharmacy Technology
                          Not Confirmed

                          Details : The financing aims to fund the HOOKIPA investigational product HB-500, which is a 2-vector arenaviral therapeutic vaccine. It is currently under evaluation as a component of a potential curative regimen for HIV infections.

                          Brand Name : HB-500

                          Molecule Type : Vaccine

                          Upfront Cash : Undisclosed

                          December 21, 2023

                          Lead Product(s) : HB-500

                          Therapeutic Area : Infections and Infectious Diseases

                          Highest Development Status : IND Enabling

                          Sponsor : Gilead Sciences

                          Deal Size : $21.2 million

                          Deal Type : Financing

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                          05

                          The Pharmacy Technology
                          Not Confirmed
                          The Pharmacy Technology
                          Not Confirmed

                          Details : HB-500 is an alternating, 2-vector novel arenaviral therapeutic vaccine which is under clinical development for the treatment of human immunodeficiency virus (HIV).

                          Brand Name : HB-500

                          Molecule Type : Vaccine

                          Upfront Cash : Not Applicable

                          November 20, 2023

                          Lead Product(s) : HB-500

                          Therapeutic Area : Infections and Infectious Diseases

                          Highest Development Status : IND Enabling

                          Sponsor : Gilead Sciences

                          Deal Size : Not Applicable

                          Deal Type : Not Applicable

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                          06

                          The Pharmacy Technology
                          Not Confirmed
                          The Pharmacy Technology
                          Not Confirmed

                          Details : HB-200 is HOOKIPA’s lead oncology candidate engineered with the its proprietary replicating arenaviral vector platform. HB-200 in combination with pembrolizumab received Fast Track Designation for the treatment of 1st-line recurrent/metastatic HPV16+ h...

                          Brand Name : HB-200

                          Molecule Type : Vaccine

                          Upfront Cash : Not Applicable

                          May 31, 2023

                          Lead Product(s) : HB-200,Pembrolizumab

                          Therapeutic Area : Oncology

                          Highest Development Status : Phase II

                          Sponsor : Not Applicable

                          Deal Size : Not Applicable

                          Deal Type : Not Applicable

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                          07

                          The Pharmacy Technology
                          Not Confirmed
                          The Pharmacy Technology
                          Not Confirmed

                          Details : HB-400 (GS-2829) is an alternating, 2-vector non-replicating arenaviral therapeutic vaccine which uses the lymphocytic choriomeningitis virus and pichinde virus as arenaviral backbones,for the treatment of chronic hepatitis B.

                          Brand Name : HB-400

                          Molecule Type : Vaccine

                          Upfront Cash : Not Applicable

                          May 09, 2023

                          Lead Product(s) : GS-2829,GS-6779

                          Therapeutic Area : Infections and Infectious Diseases

                          Highest Development Status : Phase I

                          Sponsor : Gilead Sciences

                          Deal Size : Not Applicable

                          Deal Type : Not Applicable

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                          08

                          The Pharmacy Technology
                          Not Confirmed
                          The Pharmacy Technology
                          Not Confirmed

                          Details : The collaboration between HOOKIPA and Roche is to license and develop HB-700, a novel arenaviral immunotherapy for KRAS-mutated cancers and an option for a second, undisclosed arenaviral immunotherapy. HOOKIPA is conducting research through Phase 1b for ...

                          Brand Name : HB-700

                          Molecule Type : Large molecule

                          Upfront Cash : $25.0 million

                          February 13, 2023

                          Lead Product(s) : HB-700

                          Therapeutic Area : Oncology

                          Highest Development Status : Preclinical

                          Sponsor : F. Hoffmann-La Roche

                          Deal Size : $955.0 million

                          Deal Type : Collaboration

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                          09

                          The Pharmacy Technology
                          Not Confirmed
                          The Pharmacy Technology
                          Not Confirmed

                          Details : Following the submission of the clinical trial application (IND equivalent) for HB-400, a Hepatitis B therapeutic, in 2022, HOOKIPA expects the first patient to be dosed in a Phase 1 clinical trial during 2023.

                          Brand Name : HB-400

                          Molecule Type : Vaccine

                          Upfront Cash : $10.0 million

                          January 04, 2023

                          Lead Product(s) : HB-400

                          Therapeutic Area : Infections and Infectious Diseases

                          Highest Development Status : Preclinical

                          Sponsor : Gilead Sciences

                          Deal Size : $410.0 million

                          Deal Type : Collaboration

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                          10

                          The Pharmacy Technology
                          Not Confirmed
                          The Pharmacy Technology
                          Not Confirmed

                          Details : HOOKIPA will conduct development, based on its proprietary arenavirus platform, through Phase 1b for HB-700, an arenaviral immunotherapy for treatment of KRAS-mutated cancers and option to license a second undisclosed novel arenaviral immunotherapy.

                          Brand Name : HB-700

                          Molecule Type : Large molecule

                          Upfront Cash : $25.0 million

                          October 20, 2022

                          Lead Product(s) : HB-700

                          Therapeutic Area : Oncology

                          Highest Development Status : Preclinical

                          Sponsor : F. Hoffmann-La Roche

                          Deal Size : $955.0 million

                          Deal Type : Collaboration

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