[{"orgOrder":0,"company":"Hovione","sponsor":"Ligand Pharmaceuticals","pharmaFlowCategory":"D","therapeuticArea":"Infections and Infectious Diseases","country":"PORTUGAL","productType":"Other Large Molecule","year":"2020","type":"Partnership","leadProduct":"Modified Cyclodextrin","moa":"Undisclosed","graph1":"Infections and Infectious Diseases","graph2":"Approved FDF","graph3":"Hovione","amount2":0,"highestDevelopmentShortName":"","therapeuticAreaShortName":"Infectious Diseases","amount2New":0,"dosageForm":"Undisclosed","sponsorNew":"Hovione \/ Ligand Pharmaceuticals","highestDevelopmentStatusID":"15","companyTruncated":"Hovione \/ Ligand Pharmaceuticals"},{"orgOrder":0,"company":"Hovione","sponsor":"Inapplicable","pharmaFlowCategory":"DU","therapeuticArea":"Ophthalmology","country":"PORTUGAL","productType":"Other Small Molecule","year":"2021","type":"Inapplicable","leadProduct":"Minocycline Hydrochloride","moa":"Protein Biosynthesis","graph1":"Ophthalmology","graph2":"Phase II","graph3":"Hovione","amount2":0,"highestDevelopmentShortName":"Ph II","therapeuticAreaShortName":"Ophthalmology","amount2New":0,"dosageForm":"Ophthalmic Ointment","sponsorNew":"Hovione \/ Inapplicable","highestDevelopmentStatusID":"8","companyTruncated":"Hovione \/ Inapplicable"},{"orgOrder":0,"company":"Hovione","sponsor":"Ji Xing Pharmaceuticals","pharmaFlowCategory":"D","therapeuticArea":"Ophthalmology","country":"PORTUGAL","productType":"Other Small Molecule","year":"2022","type":"Licensing Agreement","leadProduct":"JX08","moa":"Undisclosed","graph1":"Ophthalmology","graph2":"Preclinical","graph3":"Hovione","amount2":0,"highestDevelopmentShortName":"Preclinical","therapeuticAreaShortName":"Ophthalmology","amount2New":0,"dosageForm":"Spray","sponsorNew":"Hovione \/ Ji Xing Pharmaceuticals","highestDevelopmentStatusID":"4","companyTruncated":"Hovione \/ Ji Xing Pharmaceuticals"}]

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                          Top Deals by Deal Size (USD bn)

                          01

                          Pharma Live Expo
                          Not Confirmed
                          Pharma Live Expo
                          Not Confirmed

                          Details : Under the license agreement, JIXING will receive global rights to JX08 and lead the full life cycle of development from preclinical through commercialization.

                          Product Name : JX08

                          Product Type : Other Small Molecule

                          Upfront Cash : Undisclosed

                          September 05, 2022

                          Lead Product(s) : JX08

                          Therapeutic Area : Ophthalmology

                          Highest Development Status : Preclinical

                          Sponsor : Ji Xing Pharmaceuticals

                          Deal Size : Undisclosed

                          Deal Type : Licensing Agreement

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                          02

                          Pharma Live Expo
                          Not Confirmed
                          Pharma Live Expo
                          Not Confirmed

                          Details : This is the first dry eye therapy targeting MGD patients with ocular inflammation demonstrated by an MMP-9 based diagnostic and the first and only ophthalmic formulation of minocycline in clinical development, contingently named Meizuvo®.

                          Product Name : HY02

                          Product Type : Other Small Molecule

                          Upfront Cash : Inapplicable

                          March 17, 2021

                          Lead Product(s) : Minocycline Hydrochloride

                          Therapeutic Area : Ophthalmology

                          Highest Development Status : Phase II

                          Sponsor : Inapplicable

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

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                          03

                          Pharma Live Expo
                          Not Confirmed
                          Pharma Live Expo
                          Not Confirmed

                          Details : The partnership aims to significantly ramp up the production output of Captisol®. Captisol®, a Ligand product and a chemically modified cyclodextrin proven to improve the solubility and stability of drugs.

                          Product Name : Captisol

                          Product Type : Other Large Molecule

                          Upfront Cash : Undisclosed

                          September 23, 2020

                          Lead Product(s) : Modified Cyclodextrin

                          Therapeutic Area : Infections and Infectious Diseases

                          Highest Development Status : Approved FDF

                          Sponsor : Ligand Pharmaceuticals

                          Deal Size : Undisclosed

                          Deal Type : Partnership

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