Year
DEALS // DEV.
Country
Therapeutic Area
Study Phase
Deal Type
Product Type
Dosage Form
Lead Product
Target
Hummingbird Bioscience Licenses Novel Antibodies to Immunome
Details : Under the terms of the license agreement, Immunome will be responsible for the research, development, manufacturing and commercialization of products incorporating these antibodies.
Product Name : Undisclosed
Product Type : Antibody
Upfront Cash : Undisclosed
January 07, 2025
Lead Product(s) : HMBD-501
Therapeutic Area : Oncology
Study Phase : Preclinical
Sponsor : Endeavor Biomedicines
Deal Size : $430.0 million
Deal Type : Licensing Agreement
Details : Under the agreement, Endeavor has acquired exclusive worldwide rights to Hummingbird Bio’s HMBD-501, a next-generation HER3-targeted antibody-drug conjugate (ADC).
Product Name : HMBD-501
Product Type : Other Large Molecule
Upfront Cash : Undisclosed
October 19, 2023
Lead Product(s) : HMBD-501
Therapeutic Area : Oncology
Highest Development Status : Preclinical
Sponsor : Endeavor Biomedicines
Deal Size : $430.0 million
Deal Type : Licensing Agreement
Lead Product(s) : HMBD-001
Therapeutic Area : Oncology
Study Phase : Phase I/ Phase II
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
Details : HMBD-001 is an anti-HER3 antibody in development that has the potential to fully block both ligand-dependent and independent HER3 activation and oncogenic signaling, by targeting a key epitope located at the interface where HER3 forms heterodimers with H...
Product Name : HMBD-001
Product Type : Antibody
Upfront Cash : Inapplicable
June 03, 2023
Lead Product(s) : HMBD-001
Therapeutic Area : Oncology
Highest Development Status : Phase I/ Phase II
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
Lead Product(s) : HMBD-001,Cetuximab
Therapeutic Area : Oncology
Study Phase : Preclinical
Sponsor : Merck & Co
Deal Size : Undisclosed
Deal Type : Collaboration
Details : Under the collaboration, Hummingbird will evaluate its potentially best-in-class HER3-targeting antibody, HMBD-001, in combination with SoC chemotherapy with or without Merck's cetuximab, anti-EGFR mAb, in patients with sqNSCLC in a Phase 1b clinical tri...
Product Name : HMBD-001
Product Type : Antibody
Upfront Cash : Undisclosed
May 15, 2023
Lead Product(s) : HMBD-001,Cetuximab
Therapeutic Area : Oncology
Highest Development Status : Preclinical
Sponsor : Merck & Co
Deal Size : Undisclosed
Deal Type : Collaboration
Lead Product(s) : HMBD-001
Therapeutic Area : Oncology
Study Phase : Phase I/ Phase II
Sponsor : George Clinical
Deal Size : Undisclosed
Deal Type : Agreement
George Clinical to Support Hummingbird’s Phase 1 Oncology Trials
Details : George Clinical will provide its full-service CRO expertise for the Hummingbird sponsored trials, including HMBD-001, a unique antibody engineered to bind strongly and specifically to the dimerization interface of HER3, developed with its Rational Antibo...
Product Name : HMBD-001
Product Type : Antibody
Upfront Cash : Undisclosed
April 05, 2023
Lead Product(s) : HMBD-001
Therapeutic Area : Oncology
Highest Development Status : Phase I/ Phase II
Sponsor : George Clinical
Deal Size : Undisclosed
Deal Type : Agreement
Lead Product(s) : HMBD-002,Pembrolizumab
Therapeutic Area : Oncology
Study Phase : Phase I
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
Details : HMBD-002 is an investigational IgG4 anti-VISTA antagonist antibody to target the region where VISTA interacts with binding partners that have been shown to play an important role in modulating T cell activity, potentially unlocking the immune system to a...
Product Name : HMBD-002
Product Type : Antibody
Upfront Cash : Inapplicable
September 19, 2022
Lead Product(s) : HMBD-002,Pembrolizumab
Therapeutic Area : Oncology
Highest Development Status : Phase I
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
Lead Product(s) : HMBD-002,Pembrolizumab
Therapeutic Area : Oncology
Study Phase : Phase I
Sponsor : Merck & Co
Deal Size : Undisclosed
Deal Type : Collaboration
Details : Under this collaboration, Hummingbird will evaluate the safety, tolerability, and anti-tumor activity of its novel anti-VISTA antibody, HMBD-002, in combination with KEYTRUDA ® (pembrolizumab).
Product Name : HMBD-002
Product Type : Antibody
Upfront Cash : Undisclosed
October 25, 2021
Lead Product(s) : HMBD-002,Pembrolizumab
Therapeutic Area : Oncology
Highest Development Status : Phase I
Sponsor : Merck & Co
Deal Size : Undisclosed
Deal Type : Collaboration
Lead Product(s) : HMBD-001
Therapeutic Area : Oncology
Study Phase : Preclinical
Sponsor : Organovo Holdings
Deal Size : $125.0 million
Deal Type : Series C Financing
Hummingbird Bioscience Raises US$125 Million in Series C Financing
Details : Proceeds from the financing will be used to advance the clinical development of Hummingbird’s lead assets including, HMBD-001, a best-in-class HER3 antibody for NRG1-fusion and HER3-driven tumors, and HMBD-002, an anti-VISTA neutralizing antibody.
Product Name : HMBD-001
Product Type : Antibody
Upfront Cash : Undisclosed
May 18, 2021
Lead Product(s) : HMBD-001
Therapeutic Area : Oncology
Highest Development Status : Preclinical
Sponsor : Organovo Holdings
Deal Size : $125.0 million
Deal Type : Series C Financing
Lead Product(s) : HMBD-001
Therapeutic Area : Oncology
Study Phase : Preclinical
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
Details : HMBD-001 is a novel antibody with a unique, differentiated mechanism of action that fully inhibits HER3 activation of the MAPK/PI3K tumor growth signaling pathway.
Product Name : HMBD-001
Product Type : Antibody
Upfront Cash : Inapplicable
February 08, 2021
Lead Product(s) : HMBD-001
Therapeutic Area : Oncology
Highest Development Status : Preclinical
Sponsor : Inapplicable
Deal Size : Inapplicable
Deal Type : Inapplicable
Lead Product(s) : HMBD-001
Therapeutic Area : Oncology
Study Phase : Preclinical
Sponsor : SK Holdings, Heritas Capital, SEEDS Enterprise
Deal Size : $25.0 million
Deal Type : Series B Financing
Hummingbird Closes Extended Series B Funding Round of $25M
Details : Hummingbird will use the new funds to accelerate development of new candidates into clinical trials and strengthen its scientific and research and development capabilities.
Product Name : HMBD-001
Product Type : Antibody
Upfront Cash : Undisclosed
October 05, 2020
Lead Product(s) : HMBD-001
Therapeutic Area : Oncology
Highest Development Status : Preclinical
Sponsor : SK Holdings, Heritas Capital, SEEDS Enterprise
Deal Size : $25.0 million
Deal Type : Series B Financing