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    [{"orgOrder":0,"company":"Acura Pharmaceuticals","sponsor":"Not Applicable","pharmaFlowCategory":"DU","therapeuticArea":"Neurology","country":"U.S.A","productType":"Small molecule","year":"2020","type":"Not Applicable","leadProduct":"Hydrocodone Bitartrate","moa":"","graph1":"Neurology","graph2":"Preclinical","graph3":"Acura Pharmaceuticals","amount2":0,"highestDevelopmentShortName":"Preclinical","therapeuticAreaShortName":"Neurology","amount2New":0,"dosageForm":"Immediate Release Tablet","sponsorNew":"Acura Pharmaceuticals \/ Not Applicable","highestDevelopmentStatusID":"4","companyTruncated":"Acura Pharmaceuticals \/ Not Applicable"},{"orgOrder":0,"company":"Acura Pharmaceuticals","sponsor":"Not Applicable","pharmaFlowCategory":"DU","therapeuticArea":"Neurology","country":"","productType":"Small molecule","year":"2021","type":"Not Applicable","leadProduct":"Hydrocodone Bitartrate","moa":"Mu opioid receptor","graph1":"Neurology","graph2":"Phase III","graph3":"Acura Pharmaceuticals","amount2":0,"highestDevelopmentShortName":"Ph III","therapeuticAreaShortName":"Neurology","amount2New":0,"dosageForm":"Immediate Release Tablet","sponsorNew":"Acura Pharmaceuticals \/ Not Applicable","highestDevelopmentStatusID":"10","companyTruncated":"Acura Pharmaceuticals \/ Not Applicable"},{"orgOrder":0,"company":"Acura Pharmaceuticals","sponsor":"Abuse Deterrent Pharma, LLC","pharmaFlowCategory":"D","therapeuticArea":"Neurology","country":"","productType":"Small molecule","year":"2021","type":"Agreement","leadProduct":"Hydrocodone Bitartrate","moa":"Mu opioid receptor","graph1":"Neurology","graph2":"Phase III","graph3":"Acura Pharmaceuticals","amount2":0,"highestDevelopmentShortName":"Ph III","therapeuticAreaShortName":"Neurology","amount2New":0,"dosageForm":"Immediate Release Tablet","sponsorNew":"Acura Pharmaceuticals \/ Abuse Deterrent Pharma, LLC","highestDevelopmentStatusID":"10","companyTruncated":"Acura Pharmaceuticals \/ Abuse Deterrent Pharma, LLC"},{"orgOrder":0,"company":"Acura Pharmaceuticals","sponsor":"Not Applicable","pharmaFlowCategory":"DU","therapeuticArea":"Neurology","country":"","productType":"Small molecule","year":"2022","type":"Not Applicable","leadProduct":"Hydrocodone Bitartrate","moa":"Mu opioid receptor","graph1":"Neurology","graph2":"Phase III","graph3":"Acura Pharmaceuticals","amount2":0,"highestDevelopmentShortName":"Ph III","therapeuticAreaShortName":"Neurology","amount2New":0,"dosageForm":"Immediate Release Tablet","sponsorNew":"Acura Pharmaceuticals \/ Not Applicable","highestDevelopmentStatusID":"10","companyTruncated":"Acura Pharmaceuticals \/ Not Applicable"},{"orgOrder":0,"company":"Acura Pharmaceuticals","sponsor":"Abuse Deterrent Pharmaceuticals","pharmaFlowCategory":"D","therapeuticArea":"Neurology","country":"","productType":"Small molecule","year":"2022","type":"Licensing Agreement","leadProduct":"Hydrocodone Bitartrate","moa":"Opioid receptor","graph1":"Neurology","graph2":"Phase III","graph3":"Acura Pharmaceuticals","amount2":0,"highestDevelopmentShortName":"Ph III","therapeuticAreaShortName":"Neurology","amount2New":0,"dosageForm":"Immediate Release Tablet","sponsorNew":"Acura Pharmaceuticals \/ Abuse Deterrent Pharmaceuticals","highestDevelopmentStatusID":"10","companyTruncated":"Acura Pharmaceuticals \/ Abuse Deterrent Pharmaceuticals"}]

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                            01

                            Acura Pharmaceuticals

                            U.S.A arrow
                            euroPLX 86 Munich
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                            Acura Pharmaceuticals

                            U.S.A arrow
                            euroPLX 86 Munich
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                            Lead Product(s) : Hydrocodone Bitartrate,Paracetamol

                            Therapeutic Area : Neurology

                            Study Phase : Undisclosed

                            Sponsor : Abuse Deterrent Pharmaceuticals

                            Deal Size : Undisclosed

                            Deal Type : Licensing Agreement

                            DEALS_DEV arrow-down

                            Acura Pharmaceuticals and AD Pharma Amend License to LIMITx™ LTX-03

                            Details : LIMITx™ LTX-03, works by neutralizing stomach acid with buffering ingredients as increasing numbers of tablets are swallowed thereby reducing the stomach acid available to cause the release and systemic absorption of active from micro-particles contain...

                            Brand Name : LTX-03

                            Molecule Type : Small molecule

                            Upfront Cash : Undisclosed

                            March 01, 2022

                            Lead Product(s) : Hydrocodone Bitartrate,Paracetamol

                            Therapeutic Area : Neurology

                            Highest Development Status : Undisclosed

                            Sponsor : Abuse Deterrent Pharmaceuticals

                            Deal Size : Undisclosed

                            Deal Type : Licensing Agreement

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                            02

                            Acura Pharmaceuticals

                            U.S.A arrow
                            euroPLX 86 Munich
                            Not Confirmed

                            Acura Pharmaceuticals

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                            euroPLX 86 Munich
                            Not Confirmed
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                            Lead Product(s) : Hydrocodone Bitartrate,Paracetamol

                            Therapeutic Area : Neurology

                            Study Phase : Undisclosed

                            Sponsor : Not Applicable

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

                            DEALS_DEV arrow-down

                            Acura Pharmaceuticals Provides Development Update on LTX-03

                            Details : In clinical study, formulations of LTX-03 demonstrated, under fasted conditions, analgesic levels of hydrocodone in the blood when taken at a recommended one or two tablet dose but reduced the maximum blood level up to 34% when exposed to higher buffer i...

                            Brand Name : LTX-03

                            Molecule Type : Small molecule

                            Upfront Cash : Not Applicable

                            February 14, 2022

                            Lead Product(s) : Hydrocodone Bitartrate,Paracetamol

                            Therapeutic Area : Neurology

                            Highest Development Status : Undisclosed

                            Sponsor : Not Applicable

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

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                            03

                            Acura Pharmaceuticals

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                            euroPLX 86 Munich
                            Not Confirmed

                            Acura Pharmaceuticals

                            U.S.A arrow
                            euroPLX 86 Munich
                            Not Confirmed
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                            Lead Product(s) : Hydrocodone Bitartrate,Paracetamol

                            Therapeutic Area : Neurology

                            Study Phase : Phase III

                            Sponsor : Abuse Deterrent Pharma, LLC

                            Deal Size : Undisclosed

                            Deal Type : Agreement

                            DEALS_DEV arrow-down

                            Acura Pharmaceuticals and AD Pharma Amend License to LIMITx™ LTX-03

                            Details : LTX-03 is an immediate-release hydrocodone bitartrate with acetaminophen tablet. The agreement aims at extending the FDA Acceptance Date for LTX-03 to February 28, 2022.

                            Brand Name : LTX-03

                            Molecule Type : Small molecule

                            Upfront Cash : Undisclosed

                            July 26, 2021

                            Lead Product(s) : Hydrocodone Bitartrate,Paracetamol

                            Therapeutic Area : Neurology

                            Highest Development Status : Phase III

                            Sponsor : Abuse Deterrent Pharma, LLC

                            Deal Size : Undisclosed

                            Deal Type : Agreement

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                            04

                            Acura Pharmaceuticals

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                            euroPLX 86 Munich
                            Not Confirmed

                            Acura Pharmaceuticals

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                            euroPLX 86 Munich
                            Not Confirmed
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                            Lead Product(s) : Hydrocodone Bitartrate,Paracetamol

                            Therapeutic Area : Neurology

                            Study Phase : IND Enabling

                            Sponsor : Not Applicable

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

                            DEALS_DEV arrow-down

                            Acura Pharmaceuticals Provides Development Update on LTX-03

                            Details : LTX-03 (hydrocodone with acetaminophen) demonstrated, under fasted conditions, analgesic levels of hydrocodone in the blood when taken at a recommended one or two tablet dose.

                            Brand Name : LTX-03

                            Molecule Type : Small molecule

                            Upfront Cash : Not Applicable

                            June 07, 2021

                            Lead Product(s) : Hydrocodone Bitartrate,Paracetamol

                            Therapeutic Area : Neurology

                            Highest Development Status : IND Enabling

                            Sponsor : Not Applicable

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

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                            05

                            Acura Pharmaceuticals

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                            euroPLX 86 Munich
                            Not Confirmed

                            Acura Pharmaceuticals

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                            euroPLX 86 Munich
                            Not Confirmed
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                            Lead Product(s) : Hydrocodone Bitartrate,Paracetamol

                            Therapeutic Area : Neurology

                            Study Phase : Preclinical

                            Sponsor : Not Applicable

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

                            DEALS_DEV arrow-down

                            Acura Pharmaceuticals Provides an Update on the Development of LTX-03

                            Details : In conjunction with a third party formulation developer, the formulation and manufacturing process for LTX-03 has been optimized for commercial scale.

                            Brand Name : Undisclosed

                            Molecule Type : Small molecule

                            Upfront Cash : Not Applicable

                            January 02, 2020

                            Lead Product(s) : Hydrocodone Bitartrate,Paracetamol

                            Therapeutic Area : Neurology

                            Highest Development Status : Preclinical

                            Sponsor : Not Applicable

                            Deal Size : Not Applicable

                            Deal Type : Not Applicable

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