Year
DEALS // DEV.
Country
Therapeutic Area
Study Phase
Deal Type
Product Type
Dosage Form
Lead Product
Target
Lead Product(s) : MK-5684,Dexamethasone,Hydrocortisone
Therapeutic Area : Oncology
Study Phase : Phase III
Sponsor : Merck & Co
Deal Size : Not Applicable
Deal Type : Not Applicable
Phase 3 Clinical Trials with ODM-208 (MK-5684) posted to ClinicalTrials.gov Database
Details : ODM-208 (or MK-5684) is an investigational oral, non-steroidal and selective inhibitor of the CYP11A1 enzyme discovered and developed by Orion for the treatment of hormone-dependent cancers, such as metastatic castration-resistant prostate cancer.
Brand Name : ODM-208
Molecule Type : Small molecule
Upfront Cash : Not Applicable
November 21, 2023
Lead Product(s) : MK-5684,Dexamethasone,Hydrocortisone
Therapeutic Area : Oncology
Highest Development Status : Phase III
Sponsor : Merck & Co
Deal Size : Not Applicable
Deal Type : Not Applicable
Lead Product(s) : Hydrocortisone
Therapeutic Area : Endocrinology
Study Phase : Phase III
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Eton Pharmaceuticals’ ET-400 NDA Accepted by FDA
Details : ET-400 is Eton’s proprietary patented formulation of hydrocortisone oral solution. Company has submitted NDA for ET-400 use in endocrine system disorders.
Brand Name : ET-400
Molecule Type : Small molecule
Upfront Cash : Not Applicable
July 15, 2024
Lead Product(s) : Hydrocortisone
Therapeutic Area : Endocrinology
Highest Development Status : Phase III
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Lead Product(s) : Hydrocortisone
Therapeutic Area : Endocrinology
Study Phase : Phase III
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Eton Submits New Drug Application to FDA for ET-400 (Hydrocortisone Oral Solution)
Details : ET-400 is Eton’s proprietary patented formulation of hydrocortisone oral solution. Company has submitted NDA for ET-400 use in endocrine system disorders.
Brand Name : ET-400
Molecule Type : Small molecule
Upfront Cash : Not Applicable
April 30, 2024
Lead Product(s) : Hydrocortisone
Therapeutic Area : Endocrinology
Highest Development Status : Phase III
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Lead Product(s) : Hydrocortisone
Therapeutic Area : Genetic Disease
Study Phase : Approved
Sponsor : Diurnal Group
Deal Size : Undisclosed
Deal Type : Licensing Agreement
Details : Efmody® is a modified-release preparation of hydrocortisone that has been specifically designed for the treatment of patients with CAH, a rare condition caused by a genetic deficiency of adrenal enzymes.
Brand Name : Efmody
Molecule Type : Small molecule
Upfront Cash : Undisclosed
April 26, 2022
Lead Product(s) : Hydrocortisone
Therapeutic Area : Genetic Disease
Highest Development Status : Approved
Sponsor : Diurnal Group
Deal Size : Undisclosed
Deal Type : Licensing Agreement
Lead Product(s) : Hydrocortisone
Therapeutic Area : Endocrinology
Study Phase : Phase I
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Antares Pharma Announces Positive Results From Phase I Study For ATRS-1902 For Adrenal Crisis Rescue
Details : The results of the Phase I study met its primary objective showing ATRS-1902 delivered a comparable pharmacokinetic profile and also demonstrated that ATRS-1902 was safe and well-tolerated for the treatment of acute adrenal insufficiency.
Brand Name : ATRS-1902
Molecule Type : Small molecule
Upfront Cash : Not Applicable
January 11, 2022
Lead Product(s) : Hydrocortisone
Therapeutic Area : Endocrinology
Highest Development Status : Phase I
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Lead Product(s) : Hydrocortisone
Therapeutic Area : Endocrinology
Study Phase : Approved
Sponsor : Eton Pharmaceuticals
Deal Size : Undisclosed
Deal Type : Agreement
Details : Under terms of the agreement, Tolmar’s sales force will promote ALKINDI SPRINKLE® to their pediatric endocrinology targets alongside FENSOLVI®. ALKINDI SPRINKLE® (hydrocortisone) oral granules is FDA-approved as replacement therapy for Adrenocortica...
Brand Name : Alkindi Sprinkle
Molecule Type : Small molecule
Upfront Cash : Undisclosed
November 15, 2021
Lead Product(s) : Hydrocortisone
Therapeutic Area : Endocrinology
Highest Development Status : Approved
Sponsor : Eton Pharmaceuticals
Deal Size : Undisclosed
Deal Type : Agreement
Lead Product(s) : Hydrocortisone
Therapeutic Area : Genetic Disease
Study Phase : Approved
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Details : Efmody® is a preparation of hydrocortisone that has been specifically designed for patients with CAH, a rare condition caused by deficiency of adrenal enzymes, most commonly 21-hydroxylase.
Brand Name : Efmody
Molecule Type : Small molecule
Upfront Cash : Not Applicable
September 13, 2021
Lead Product(s) : Hydrocortisone
Therapeutic Area : Genetic Disease
Highest Development Status : Approved
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Lead Product(s) : Hydrocortisone
Therapeutic Area : Endocrinology
Study Phase : IND Enabling
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Antares Pharma FDA Acceptance of IND Application for ATRS-1902
Details : The active IND enables Antares to initiate a Phase 1 clinical study for ATRS-1902 for the treatment of acute adrenal insufficiency, known as adrenal crisis, in adults and adolescents, using a novel proprietary auto-injector platform to deliver hydrocorti...
Brand Name : ATRS-1902
Molecule Type : Small molecule
Upfront Cash : Not Applicable
July 22, 2021
Lead Product(s) : Hydrocortisone
Therapeutic Area : Endocrinology
Highest Development Status : IND Enabling
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Lead Product(s) : Hydrocortisone
Therapeutic Area : Endocrinology
Study Phase : Undisclosed
Sponsor : Crossject
Deal Size : $11.0 million
Deal Type : Licensing Agreement
Details : The ready to use ZENEO® Hydrocortisone will provide a 2-step rescue kit developed for a simple and intuitive autoinjection even by non healthcare professionals.
Brand Name : ZENEO Hydrocortisone
Molecule Type : Small molecule
Upfront Cash : Undisclosed
June 15, 2021
Lead Product(s) : Hydrocortisone
Therapeutic Area : Endocrinology
Highest Development Status : Undisclosed
Sponsor : Crossject
Deal Size : $11.0 million
Deal Type : Licensing Agreement
Lead Product(s) : Hydrocortisone
Therapeutic Area : Genetic Disease
Study Phase : Approved
Sponsor : Citrine Medicine
Deal Size : $2.2 million
Deal Type : Partnership
Diurnal Triggers $1.25m in Milestone Payments from Citrine Medicine
Details : The $1.25 million milestone payment has been triggered as a result of the recent European Commission’s approval for Efmody® (hydrocortisone modified-release hard capsules) and the attainment by Citrine of certain development milestones in China for A...
Brand Name : Efmody
Molecule Type : Small molecule
Upfront Cash : $1.0 million
June 01, 2021
Lead Product(s) : Hydrocortisone
Therapeutic Area : Genetic Disease
Highest Development Status : Approved
Sponsor : Citrine Medicine
Deal Size : $2.2 million
Deal Type : Partnership
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