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Biopharma","sponsor":"Inapplicable","pharmaFlowCategory":"DU","therapeuticArea":"Oncology","country":"CHINA","productType":"Antibody","year":"2022","type":"Inapplicable","leadProduct":"TJ-CD4B","moa":"CLDN18.2\/4-1BB","graph1":"Oncology","graph2":"Phase I","graph3":"I-Mab Biopharma","amount2":0,"highestDevelopmentShortName":"Ph I","therapeuticAreaShortName":"Oncology","amount2New":0,"dosageForm":"Undisclosed","sponsorNew":"I-Mab Biopharma \/ Inapplicable","highestDevelopmentStatusID":"6","companyTruncated":"I-Mab Biopharma \/ Inapplicable"},{"orgOrder":0,"company":"I-Mab Biopharma","sponsor":"ABL Bio","pharmaFlowCategory":"DU","therapeuticArea":"Oncology","country":"CHINA","productType":"Other Large Molecule","year":"2023","type":"Inapplicable","leadProduct":"TJ-L14B","moa":"PD-L1\/4-1BB","graph1":"Oncology","graph2":"Phase I","graph3":"I-Mab Biopharma","amount2":0,"highestDevelopmentShortName":"Ph I","therapeuticAreaShortName":"Oncology","amount2New":0,"dosageForm":"Intravenous Infusion","sponsorNew":"I-Mab Biopharma \/ ABL Bio","highestDevelopmentStatusID":"6","companyTruncated":"I-Mab Biopharma \/ ABL Bio"},{"orgOrder":0,"company":"I-Mab Biopharma","sponsor":"Inapplicable","pharmaFlowCategory":"DU","therapeuticArea":"Oncology","country":"CHINA","productType":"Antibody","year":"2022","type":"Inapplicable","leadProduct":"Azacitidine","moa":"||CD47","graph1":"Oncology","graph2":"Phase III","graph3":"I-Mab Biopharma","amount2":0,"highestDevelopmentShortName":"Ph III","therapeuticAreaShortName":"Oncology","amount2New":0,"dosageForm":"Intravenous Infusion","sponsorNew":"I-Mab Biopharma \/ Inapplicable","highestDevelopmentStatusID":"10","companyTruncated":"I-Mab Biopharma \/ Inapplicable"},{"orgOrder":0,"company":"I-Mab Biopharma","sponsor":"Inapplicable","pharmaFlowCategory":"DU","therapeuticArea":"Oncology","country":"CHINA","productType":"Antibody","year":"2022","type":"Inapplicable","leadProduct":"Atezolizumab","moa":"||CD73","graph1":"Oncology","graph2":"Phase II","graph3":"I-Mab Biopharma","amount2":0,"highestDevelopmentShortName":"Ph II","therapeuticAreaShortName":"Oncology","amount2New":0,"dosageForm":"Intravenous Injection","sponsorNew":"I-Mab Biopharma \/ Inapplicable","highestDevelopmentStatusID":"8","companyTruncated":"I-Mab Biopharma \/ Inapplicable"},{"orgOrder":0,"company":"I-Mab Biopharma","sponsor":"Inapplicable","pharmaFlowCategory":"DU","therapeuticArea":"Oncology","country":"CHINA","productType":"Antibody","year":"2021","type":"Inapplicable","leadProduct":"Atezolizumab","moa":"||CD73","graph1":"Oncology","graph2":"Phase I\/ Phase II","graph3":"I-Mab Biopharma","amount2":0,"highestDevelopmentShortName":"Ph 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Bio","pharmaFlowCategory":"DU","therapeuticArea":"Oncology","country":"CHINA","productType":"Antibody","year":"2025","type":"Inapplicable","leadProduct":"Givastomig","moa":"||CLDN 18.2","graph1":"Oncology","graph2":"Phase I","graph3":"I-Mab Biopharma","amount2":0,"highestDevelopmentShortName":"Ph I","therapeuticAreaShortName":"Oncology","amount2New":0,"dosageForm":"Intravenous","sponsorNew":"I-Mab Biopharma \/ ABL Bio","highestDevelopmentStatusID":"6","companyTruncated":"I-Mab Biopharma \/ ABL Bio"}]

Find Clinical Drug Pipeline Developments & Deals by I-Mab Biopharma

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                          Therapeutic Area by Lead Product

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                          Top Deals by Deal Size (USD bn)

                          01

                          Interphex
                          Not Confirmed
                          Interphex
                          Not Confirmed

                          Details : TJ033721 (givastomig) is a potential best-in-class, Claudin 18.2 (CLDN18.2) x 4-1BB bispecific antibody, targeting CLDN18.2-positive tumor cells.

                          Product Name : TJ033721

                          Product Type : Antibody

                          Upfront Cash : Inapplicable

                          March 07, 2025

                          Lead Product(s) : Givastomig,Nivolumab

                          Therapeutic Area : Oncology

                          Highest Development Status : Phase I

                          Sponsor : ABL Bio

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

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                          02

                          Interphex
                          Not Confirmed
                          Interphex
                          Not Confirmed

                          Details : TJ033721 (givastomig) is a bispecific antibody targeting CLDN18.2-positive tumor cells. It is being investigated as a first-line metastatic gastric cancers and other solid cancers.

                          Product Name : TJ033721

                          Product Type : Antibody

                          Upfront Cash : Inapplicable

                          January 06, 2025

                          Lead Product(s) : Givastomig

                          Therapeutic Area : Oncology

                          Highest Development Status : Phase I

                          Sponsor : Inapplicable

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

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                          03

                          Interphex
                          Not Confirmed
                          Interphex
                          Not Confirmed

                          Details :

                          Product Name : TJ101

                          Product Type : Hormone

                          Upfront Cash : Undisclosed

                          July 02, 2024

                          Lead Product(s) : Eftansomatropin Alpha

                          Therapeutic Area : Endocrinology

                          Highest Development Status : Phase III

                          Sponsor : I-Mab Hangzhou Company

                          Deal Size : $80.0 million

                          Deal Type : Divestment

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                          04

                          Interphex
                          Not Confirmed
                          Interphex
                          Not Confirmed

                          Details : TJ-L14B/ABL503, is a differentiated PD-L1 x 4-1BB bispecific antibody, which is investigated in patients with progressive, locally advanced or metastatic solid tumors who are relapsed or refractory following prior lines of treatment.

                          Product Name : ABL503

                          Product Type : Other Large Molecule

                          Upfront Cash : Inapplicable

                          October 10, 2023

                          Lead Product(s) : TJ-L14B

                          Therapeutic Area : Oncology

                          Highest Development Status : Phase I

                          Sponsor : ABL Bio

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

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                          05

                          Interphex
                          Not Confirmed
                          Interphex
                          Not Confirmed

                          Details :

                          Product Name : TJC4

                          Product Type : Antibody

                          Upfront Cash : $180.0 million

                          September 22, 2023

                          Lead Product(s) : Lemzoparlimab,Azacitidine

                          Therapeutic Area : Oncology

                          Highest Development Status : Phase III

                          Sponsor : AbbVie Inc

                          Deal Size : $1,940.0 million

                          Deal Type : Termination

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                          06

                          Interphex
                          Not Confirmed
                          Interphex
                          Not Confirmed

                          Details :

                          Product Name : TJC4

                          Product Type : Antibody

                          Upfront Cash : Inapplicable

                          April 24, 2023

                          Lead Product(s) : Lemzoparlimab,Azacitidine

                          Therapeutic Area : Oncology

                          Highest Development Status : Phase III

                          Sponsor : Inapplicable

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

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                          07

                          Interphex
                          Not Confirmed
                          Interphex
                          Not Confirmed

                          Details :

                          Product Name : MOR202

                          Product Type : Antibody

                          Upfront Cash : Inapplicable

                          February 11, 2023

                          Lead Product(s) : Felzartamab

                          Therapeutic Area : Immunology

                          Highest Development Status : Phase III

                          Sponsor : Inapplicable

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

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                          08

                          Interphex
                          Not Confirmed
                          Interphex
                          Not Confirmed

                          Details :

                          Product Name : TJC4

                          Product Type : Antibody

                          Upfront Cash : Inapplicable

                          October 09, 2022

                          Lead Product(s) : Lemzoparlimab,Azacitidine

                          Therapeutic Area : Oncology

                          Highest Development Status : Phase I/ Phase II

                          Sponsor : Inapplicable

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

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                          09

                          Interphex
                          Not Confirmed
                          Interphex
                          Not Confirmed

                          Details : Top-line efficacy data demonstrated that lemzoparlimab (TJ011133) combined with azacitidine showed encouraging clinical response in HR-MDS patients. Results also showed that lemzoparlimab combined with Azacitidine can be safely administered without the n...

                          Product Name : TJC4

                          Product Type : Antibody

                          Upfront Cash : Inapplicable

                          September 13, 2022

                          Lead Product(s) : Lemzoparlimab,Azacitidine

                          Therapeutic Area : Oncology

                          Highest Development Status : Phase I/ Phase II

                          Sponsor : Inapplicable

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

                          blank

                          10

                          Interphex
                          Not Confirmed
                          Interphex
                          Not Confirmed

                          Details : TJ-C64B is the third bispecific antibody with a conditional T cell engager based on 4-1BB-activation platform. It binds simultaneously to Claudin 6 (CLDN6)-expressing cancer cells and the costimulatory molecule 4-1BB.

                          Product Name : TJ-C64B

                          Product Type : Antibody

                          Upfront Cash : Inapplicable

                          September 03, 2022

                          Lead Product(s) : TJ-C64B

                          Therapeutic Area : Oncology

                          Highest Development Status : Preclinical

                          Sponsor : Inapplicable

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

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