[{"orgOrder":0,"company":"Lumos Pharma","sponsor":"Not Applicable","pharmaFlowCategory":"DU","therapeuticArea":"Endocrinology","country":"","productType":"Small molecule","year":"2020","type":"Not Applicable","leadProduct":"Ibutamoren","moa":"","graph1":"Endocrinology","graph2":"Phase II","graph3":"Lumos Pharma","amount2":0,"highestDevelopmentShortName":"Ph II","therapeuticAreaShortName":"Endocrinology","amount2New":0,"dosageForm":"Tablet","sponsorNew":"Lumos Pharma \/ Not Applicable","highestDevelopmentStatusID":"8","companyTruncated":"Lumos Pharma \/ Not Applicable"},{"orgOrder":0,"company":"Lumos Pharma","sponsor":"Not Applicable","pharmaFlowCategory":"DU","therapeuticArea":"Endocrinology","country":"","productType":"Small molecule","year":"2021","type":"Not Applicable","leadProduct":"Ibutamoren","moa":"","graph1":"Endocrinology","graph2":"Phase II","graph3":"Lumos Pharma","amount2":0,"highestDevelopmentShortName":"Ph 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Pharma","sponsor":"Massachusetts General Hospital","pharmaFlowCategory":"D","therapeuticArea":"Hepatology (Liver, Pancreatic, Gall Bladder)","country":"","productType":"Small molecule","year":"2022","type":"Collaboration","leadProduct":"Ibutamoren","moa":"","graph1":"Hepatology (Liver, Pancreatic, Gall Bladder)","graph2":"Phase II","graph3":"Lumos Pharma","amount2":0,"highestDevelopmentShortName":"Ph II","therapeuticAreaShortName":"Hepatology","amount2New":0,"dosageForm":"Tablet","sponsorNew":"Lumos Pharma \/ Massachusetts General Hospital","highestDevelopmentStatusID":"8","companyTruncated":"Lumos Pharma \/ Massachusetts General Hospital"},{"orgOrder":0,"company":"Lumos Pharma","sponsor":"Not Applicable","pharmaFlowCategory":"DU","therapeuticArea":"Endocrinology","country":"","productType":"Small molecule","year":"2022","type":"Not Applicable","leadProduct":"Ibutamoren","moa":"","graph1":"Endocrinology","graph2":"Phase II","graph3":"Lumos Pharma","amount2":0,"highestDevelopmentShortName":"Ph II","therapeuticAreaShortName":"Endocrinology","amount2New":0,"dosageForm":"Tablet","sponsorNew":"Lumos Pharma \/ Not Applicable","highestDevelopmentStatusID":"8","companyTruncated":"Lumos Pharma \/ Not Applicable"},{"orgOrder":0,"company":"Lumos Pharma","sponsor":"Not Applicable","pharmaFlowCategory":"DU","therapeuticArea":"Endocrinology","country":"","productType":"Small molecule","year":"2022","type":"Not Applicable","leadProduct":"Ibutamoren","moa":"","graph1":"Endocrinology","graph2":"Phase II","graph3":"Lumos Pharma","amount2":0,"highestDevelopmentShortName":"Ph II","therapeuticAreaShortName":"Endocrinology","amount2New":0,"dosageForm":"Tablet","sponsorNew":"Lumos Pharma \/ Not Applicable","highestDevelopmentStatusID":"8","companyTruncated":"Lumos Pharma \/ Not Applicable"},{"orgOrder":0,"company":"Lumos Pharma","sponsor":"Not 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Applicable","highestDevelopmentStatusID":"8","companyTruncated":"Lumos Pharma \/ Not Applicable"},{"orgOrder":0,"company":"Lumos Pharma","sponsor":"Double Point Ventures","pharmaFlowCategory":"D","therapeuticArea":"Endocrinology","country":"","productType":"Small molecule","year":"2024","type":"Merger","leadProduct":"Ibutamoren","moa":"","graph1":"Technology","graph2":"Phase I\/II","graph3":"Lumos Pharma","amount2":0,"highestDevelopmentShortName":"","therapeuticAreaShortName":"Technology","amount2New":0.94999999999999996,"dosageForm":"","sponsorNew":"Lumos Pharma \/ Double Point Ventures","highestDevelopmentStatusID":"14","companyTruncated":"Lumos Pharma \/ Double Point Ventures"}]

Find Clinical Drug Pipeline Developments & Deals for ibutamoren mesylate

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                          Top Deals by Deal Size (USD bn)

                          01

                          Medlab Asia & Asia Health
                          Not Confirmed
                          Medlab Asia & Asia Health
                          Not Confirmed

                          Details : Lumos’ lead therapeutic candidate, LUM-201 (ibutamoren ), is a novel, oral growth hormone (GH) secretagogue, currently being evaluated in multiple Phase 2 in Pediatric Growth Hormone Deficiency.

                          Brand Name : LUM-201

                          Molecule Type : Small molecule

                          Upfront Cash : Undisclosed

                          October 23, 2024

                          Lead Product(s) : Ibutamoren

                          Therapeutic Area : Endocrinology

                          Highest Development Status : Phase II

                          Sponsor : Double Point Ventures

                          Deal Size : Undisclosed

                          Deal Type : Merger

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                          02

                          Medlab Asia & Asia Health
                          Not Confirmed
                          Medlab Asia & Asia Health
                          Not Confirmed

                          Details : LUM-201 (ibutamoren mesylate), an oral growth hormone stimulating small molecule which increases growth hormone levels by mimicking the action of the hormone ghrelin and binding to one of the ghrelin receptors in the brain.

                          Brand Name : LUM-201

                          Molecule Type : Small molecule

                          Upfront Cash : Not Applicable

                          March 05, 2023

                          Lead Product(s) : Ibutamoren

                          Therapeutic Area : Endocrinology

                          Highest Development Status : Phase II

                          Sponsor : Not Applicable

                          Deal Size : Not Applicable

                          Deal Type : Not Applicable

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                          03

                          Medlab Asia & Asia Health
                          Not Confirmed
                          Medlab Asia & Asia Health
                          Not Confirmed

                          Details : LUM-201 (ibutamoren mesylate), an oral growth hormone stimulating small molecule which increases growth hormone levels by mimicking the action of the hormone ghrelin and binding to one of the ghrelin receptors in the brain.

                          Brand Name : LUM-201

                          Molecule Type : Small molecule

                          Upfront Cash : Not Applicable

                          February 28, 2023

                          Lead Product(s) : Ibutamoren

                          Therapeutic Area : Endocrinology

                          Highest Development Status : Phase II

                          Sponsor : Not Applicable

                          Deal Size : Not Applicable

                          Deal Type : Not Applicable

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                          04

                          Medlab Asia & Asia Health
                          Not Confirmed
                          Medlab Asia & Asia Health
                          Not Confirmed

                          Details : LUM-201, an oral growth hormone secretagogue, has a unique mechanism of action, targeting specific receptors on the pituitary and hypothalamus to stimulate the natural pulsatile secretion of growth hormone for moderate idiopathic PGHD patients.

                          Brand Name : LUM-201

                          Molecule Type : Small molecule

                          Upfront Cash : Not Applicable

                          December 12, 2022

                          Lead Product(s) : Ibutamoren

                          Therapeutic Area : Endocrinology

                          Highest Development Status : Phase II

                          Sponsor : Not Applicable

                          Deal Size : Not Applicable

                          Deal Type : Not Applicable

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                          05

                          Medlab Asia & Asia Health
                          Not Confirmed
                          Medlab Asia & Asia Health
                          Not Confirmed

                          Details : LUM-201, an oral growth hormone stimulating small molecule demonstrate a favorable safety profile as data from both OraGrowtH trials to date show comparable safety and tolerability to the rhGH subjects in the trials.

                          Brand Name : LUM-201

                          Molecule Type : Small molecule

                          Upfront Cash : Not Applicable

                          November 14, 2022

                          Lead Product(s) : Ibutamoren

                          Therapeutic Area : Endocrinology

                          Highest Development Status : Phase II

                          Sponsor : Not Applicable

                          Deal Size : Not Applicable

                          Deal Type : Not Applicable

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                          06

                          Medlab Asia & Asia Health
                          Not Confirmed
                          Medlab Asia & Asia Health
                          Not Confirmed

                          Details : LUM-201 (ibutamoren) is an orally administered small molecule that promotes the secretion of Growth Hormone from the pituitary gland. This investigator-initiated Phase 2 trial is a single-site, 6-month, open-label pilot study of daily oral LUM-201 in adu...

                          Brand Name : LUM-201

                          Molecule Type : Small molecule

                          Upfront Cash : Undisclosed

                          May 05, 2022

                          Lead Product(s) : Ibutamoren

                          Therapeutic Area : Hepatology (Liver, Pancreatic, Gall Bladder)

                          Highest Development Status : Phase II

                          Sponsor : Massachusetts General Hospital

                          Deal Size : Undisclosed

                          Deal Type : Collaboration

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                          07

                          Medlab Asia & Asia Health
                          Not Confirmed
                          Medlab Asia & Asia Health
                          Not Confirmed

                          Details : Lumos Pharma intends to analyze these interim datasets separately and also perform a combined analysis to increase the number of subjects in the top two LUM-201 dose cohorts.

                          Brand Name : LUM-201

                          Molecule Type : Small molecule

                          Upfront Cash : Not Applicable

                          April 11, 2022

                          Lead Product(s) : Ibutamoren

                          Therapeutic Area : Endocrinology

                          Highest Development Status : Phase II

                          Sponsor : Not Applicable

                          Deal Size : Not Applicable

                          Deal Type : Not Applicable

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                          08

                          Medlab Asia & Asia Health
                          Not Confirmed
                          Medlab Asia & Asia Health
                          Not Confirmed

                          Details : The subgroup of the Merck 020 trial specifically examined the effect LUM-201 had on the pulsatile secretion of growth hormone (GH) over 24 hours in patients with PGHD after 6 months of treatment with LUM-201, compared to that patient’s baseline GH secr...

                          Brand Name : LUM-201

                          Molecule Type : Small molecule

                          Upfront Cash : Not Applicable

                          April 27, 2021

                          Lead Product(s) : Ibutamoren

                          Therapeutic Area : Endocrinology

                          Highest Development Status : Phase II

                          Sponsor : Not Applicable

                          Deal Size : Not Applicable

                          Deal Type : Not Applicable

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                          09

                          Medlab Asia & Asia Health
                          Not Confirmed
                          Medlab Asia & Asia Health
                          Not Confirmed

                          Details : Poster 7102 presents an analysis of data from a prior clinical study comparing the peak growth hormone (GH) response of LUM-201 to that of standard GH secretagogues in children naïve-to-treatment, previously diagnosed with growth hormone deficiency (GHD...

                          Brand Name : LUM-201

                          Molecule Type : Small molecule

                          Upfront Cash : Not Applicable

                          March 20, 2021

                          Lead Product(s) : Ibutamoren

                          Therapeutic Area : Endocrinology

                          Highest Development Status : Phase II

                          Sponsor : Not Applicable

                          Deal Size : Not Applicable

                          Deal Type : Not Applicable

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                          10

                          Medlab Asia & Asia Health
                          Not Confirmed
                          Medlab Asia & Asia Health
                          Not Confirmed

                          Details : The Merck 020 study was a placebo-controlled trial of LUM-201 and recombinant human growth hormone (rhGH) in which all randomized subjects had pretreatment testing, including IGF-1 and peak GH levels determined after a single dose of LUM-201.

                          Brand Name : LUM-201

                          Molecule Type : Small molecule

                          Upfront Cash : Not Applicable

                          March 04, 2021

                          Lead Product(s) : Ibutamoren

                          Therapeutic Area : Endocrinology

                          Highest Development Status : Phase II

                          Sponsor : Not Applicable

                          Deal Size : Not Applicable

                          Deal Type : Not Applicable

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