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    [{"orgOrder":0,"company":"IconOVir Bio","sponsor":"UroGen Pharma","pharmaFlowCategory":"D","therapeuticArea":"Oncology","country":"U.S.A","productType":"Microorganism","year":"2025","type":"Acquisition","leadProduct":"ICVB-1042","moa":"Undisclosed","graph1":"Oncology","graph2":"Phase I","graph3":"IconOVir Bio","amount2":0,"highestDevelopmentShortName":"Ph I","therapeuticAreaShortName":"Oncology","amount2New":0,"dosageForm":"Intravenous Infusion","sponsorNew":"IconOVir Bio \/ UroGen Pharma","highestDevelopmentStatusID":"6","companyTruncated":"IconOVir Bio \/ UroGen Pharma"},{"orgOrder":0,"company":"IconOVir Bio","sponsor":"Inapplicable","pharmaFlowCategory":"DU","therapeuticArea":"Oncology","country":"U.S.A","productType":"Microorganism","year":"2023","type":"Inapplicable","leadProduct":"ICVB-1042","moa":"Undisclosed","graph1":"Oncology","graph2":"Phase I","graph3":"IconOVir Bio","amount2":0,"highestDevelopmentShortName":"Ph I","therapeuticAreaShortName":"Oncology","amount2New":0,"dosageForm":"Intratumoral Infusion","sponsorNew":"IconOVir Bio \/ Inapplicable","highestDevelopmentStatusID":"6","companyTruncated":"IconOVir Bio \/ Inapplicable"},{"orgOrder":0,"company":"IconOVir Bio","sponsor":"Inapplicable","pharmaFlowCategory":"DU","therapeuticArea":"Oncology","country":"U.S.A","productType":"Microorganism","year":"2022","type":"Inapplicable","leadProduct":"ICVB-1042","moa":"Undisclosed","graph1":"Oncology","graph2":"Phase I","graph3":"IconOVir Bio","amount2":0,"highestDevelopmentShortName":"Ph I","therapeuticAreaShortName":"Oncology","amount2New":0,"dosageForm":"Intratumoral Infusion","sponsorNew":"IconOVir Bio \/ Inapplicable","highestDevelopmentStatusID":"6","companyTruncated":"IconOVir Bio \/ Inapplicable"}]

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                            Lead Product(s) : ICVB-1042

                            Therapeutic Area : Oncology

                            Study Phase : Phase I

                            Sponsor : UroGen Pharma

                            Deal Size : Undisclosed

                            Deal Type : Acquisition

                            DEALS_DEV arrow-down

                            UroGen Expands with Investigational Oncolytic Virus and Research Collaborations

                            Details : UroGen expand its oncology pipeline portfolio through the acquisition of assets relating to a next-gen oncolytic virus ICVB-1042 from IconOVir Bio.

                            Product Name : ICVB-1042

                            Product Type : Microorganism

                            Upfront Cash : Undisclosed

                            February 20, 2025

                            Lead Product(s) : ICVB-1042

                            Therapeutic Area : Oncology

                            Highest Development Status : Phase I

                            Sponsor : UroGen Pharma

                            Deal Size : Undisclosed

                            Deal Type : Acquisition

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                            02

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                            Lead Product(s) : ICVB-1042

                            Therapeutic Area : Oncology

                            Study Phase : Phase I

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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                            IconOVir Bio Announces First Patient Dosed in Phase 1 Clinical Trial of its Lead Product Candidate, ICVB-1042

                            Details : ICVB-1042 is a chimeric oncolytic adenovirus, rationally designed with genomic modifications to confer tumor selective replication, broad tropism and enhanced tumor cell killing, as well as allow for either IV or intratumoral delivery.

                            Product Name : ICVB-1042

                            Product Type : Microorganism

                            Upfront Cash : Inapplicable

                            November 07, 2023

                            Lead Product(s) : ICVB-1042

                            Therapeutic Area : Oncology

                            Highest Development Status : Phase I

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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                            03

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                            Lead Product(s) : ICVB-1042

                            Therapeutic Area : Oncology

                            Study Phase : Preclinical

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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                            IconOVir Bio to Present Preclinical Data on Lead Candidate ICVB-1042 at SITC 2022

                            Details : In preclinical studies, ICVB-1042 demonstrated superior potency and selectivity compared to wildtype adenovirus and other clinical-stage Ad-based oncolytic viruses, with potent lytic replication in cancer cell lines across a broad range of tumor types.

                            Product Name : ICVB-1042

                            Product Type : Microorganism

                            Upfront Cash : Inapplicable

                            May 10, 2022

                            Lead Product(s) : ICVB-1042

                            Therapeutic Area : Oncology

                            Highest Development Status : Preclinical

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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