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                          01

                          Pharmtech & Ingredients
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                          Pharmtech & Ingredients
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                          Details : The Ideaya will focus on the novel ADC therapeutics for neoplasms through the license agreement for a potential first-in-class B7H3/PTK7 BsADC program with Biocytogen.

                          Brand Name : Undisclosed

                          Molecule Type : Large molecule

                          Upfront Cash : Undisclosed

                          July 31, 2024

                          Lead Product(s) : Undisclosed

                          Therapeutic Area : Oncology

                          Highest Development Status : Preclinical

                          Recipient : Biocytogen

                          Deal Size : $406.5 million

                          Deal Type : Licensing Agreement

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                          02

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                          Pharmtech & Ingredients
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                          Details : The net proceeds will be used to fund the ongoing clinical development of IDE397, which is in mid-stage clinical trial as monotherapy in patients with tumors with MTAP-deletion in NSCLC.

                          Brand Name : IDE397

                          Molecule Type : Small molecule

                          Upfront Cash : Undisclosed

                          July 11, 2024

                          Lead Product(s) : IDE397

                          Therapeutic Area : Oncology

                          Highest Development Status : Phase I/ Phase II

                          Sponsor : J.P. Morgan

                          Deal Size : $302.4 million

                          Deal Type : Public Offering

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                          03

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                          Not Confirmed
                          Pharmtech & Ingredients
                          Not Confirmed

                          Details : The net proceeds will be used to fund the ongoing clinical development of IDE397, which is in mid-stage clinical trial as monotherapy in patients with tumors with MTAP-deletion in NSCLC.

                          Brand Name : IDE397

                          Molecule Type : Small molecule

                          Upfront Cash : Undisclosed

                          July 09, 2024

                          Lead Product(s) : IDE397

                          Therapeutic Area : Oncology

                          Highest Development Status : Phase I/ Phase II

                          Sponsor : J.P. Morgan

                          Deal Size : $263.0 million

                          Deal Type : Public Offering

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                          04

                          Pharmtech & Ingredients
                          Not Confirmed
                          Pharmtech & Ingredients
                          Not Confirmed

                          Details : IDE397 is a potential first-in-class small molecule MAT2A inhibitor, which is being evaluated in combination with Trodelvy for the treatment of MTAP-deletion bladder cancer.

                          Brand Name : IDE397

                          Molecule Type : Small molecule

                          Upfront Cash : Not Applicable

                          June 25, 2024

                          Lead Product(s) : IDE397,Sacituzumab Govitecan

                          Therapeutic Area : Oncology

                          Highest Development Status : Phase I

                          Sponsor : Not Applicable

                          Deal Size : Not Applicable

                          Deal Type : Not Applicable

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                          05

                          Pharmtech & Ingredients
                          Not Confirmed
                          Pharmtech & Ingredients
                          Not Confirmed

                          Details : IDE397 is a potential first-in-class small molecule MAT2A inhibitor, which is being evaluated for the treatment of MTAP-deletion lung & bladder cancer.

                          Brand Name : IDE397

                          Molecule Type : Small molecule

                          Upfront Cash : Not Applicable

                          June 24, 2024

                          Lead Product(s) : IDE397

                          Therapeutic Area : Oncology

                          Highest Development Status : Phase II

                          Sponsor : Not Applicable

                          Deal Size : Not Applicable

                          Deal Type : Not Applicable

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                          06

                          Pharmtech & Ingredients
                          Not Confirmed
                          Pharmtech & Ingredients
                          Not Confirmed

                          Details : IDE397 is a selective small molecule inhibitor targeting MAT2A, investigated in patients with squamous non-small cell lung cancer having MTAP deletion.

                          Brand Name : IDE397

                          Molecule Type : Small molecule

                          Upfront Cash : Not Applicable

                          April 22, 2024

                          Lead Product(s) : IDE397,AMG 193

                          Therapeutic Area : Oncology

                          Highest Development Status : Phase I/ Phase II

                          Sponsor : Not Applicable

                          Deal Size : Not Applicable

                          Deal Type : Not Applicable

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                          07

                          Pharmtech & Ingredients
                          Not Confirmed
                          Pharmtech & Ingredients
                          Not Confirmed

                          Details : The collaboration aims to focus on the clinical development of IDE161, a small molecule inhibitor targeting PARG, in combination with Keyutra for the treatment of Endometrial Cancer.

                          Brand Name : IDE161

                          Molecule Type : Small molecule

                          Upfront Cash : Undisclosed

                          March 12, 2024

                          Lead Product(s) : IDE161,Pembrolizumab

                          Therapeutic Area : Oncology

                          Highest Development Status : IND Enabling

                          Sponsor : Merck & Co

                          Deal Size : Undisclosed

                          Deal Type : Collaboration

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                          08

                          Pharmtech & Ingredients
                          Not Confirmed
                          Pharmtech & Ingredients
                          Not Confirmed

                          Details : The net proceeds will fund ongoing clinical development of IDE196 (darovasertib), a protein kinase C (PKC) inhibitor, and crizotinib, as combination therapy in metastatic uveal melanoma, including our Phase 2/3 potential registrational clinical trial.

                          Brand Name : IDE196

                          Molecule Type : Small molecule

                          Upfront Cash : Undisclosed

                          October 27, 2023

                          Lead Product(s) : Darovasertib

                          Therapeutic Area : Oncology

                          Highest Development Status : Phase II

                          Sponsor : J.P. Morgan

                          Deal Size : $143.8 million

                          Deal Type : Public Offering

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                          09

                          Pharmtech & Ingredients
                          Not Confirmed
                          Pharmtech & Ingredients
                          Not Confirmed

                          Details : The net proceeds will fund ongoing clinical development of IDE196 (darovasertib), a protein kinase C (PKC) inhibitor, and crizotinib, as combination therapy in metastatic uveal melanoma, including our Phase 2/3 potential registrational clinical trial.

                          Brand Name : IDE196

                          Molecule Type : Small molecule

                          Upfront Cash : Undisclosed

                          October 24, 2023

                          Lead Product(s) : Darovasertib,Crizotinib

                          Therapeutic Area : Oncology

                          Highest Development Status : Phase II/ Phase III

                          Sponsor : J.P. Morgan

                          Deal Size : $125.0 million

                          Deal Type : Public Offering

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                          10

                          Pharmtech & Ingredients
                          Not Confirmed
                          Pharmtech & Ingredients
                          Not Confirmed

                          Details : IDE196 (darovasertib) is a clinical stage, potent and selective small molecule inhibitor of PKC, a protein kinase that functions downstream of the GTPases GNAQ and GNA11. Currently being developed in combination with Crizotinib for metastatic cutaneous m...

                          Brand Name : IDE196

                          Molecule Type : Small molecule

                          Upfront Cash : Not Applicable

                          October 16, 2023

                          Lead Product(s) : Darovasertib,Crizotinib

                          Therapeutic Area : Oncology

                          Highest Development Status : Phase II

                          Sponsor : Not Applicable

                          Deal Size : Not Applicable

                          Deal Type : Not Applicable

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