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Find Clinical Drug Pipeline Developments & Deals for IDRX-42

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                          Top Deals by Deal Size (USD bn)

                          01

                          BioAsia
                          Not Confirmed
                          BioAsia
                          Not Confirmed

                          Details : Through this acquisition, GSK will expand its gastrointestinal cancer portfolio with IDRX-42. IDRX-42 is a highly selective KIT TKI developed for treating gastrointestinal stromal tumors.

                          Product Name : IDRX-42

                          Product Type : Other Small Molecule

                          Upfront Cash : $1,000.0 million

                          January 13, 2025

                          Lead Product(s) : IDRX-42

                          Therapeutic Area : Oncology

                          Highest Development Status : Phase I

                          Sponsor : GSK

                          Deal Size : $1,150.0 million

                          Deal Type : Acquisition

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                          02

                          BioAsia
                          Not Confirmed
                          BioAsia
                          Not Confirmed

                          Details : IDRX-42 is a novel, KIT inhibitor that has potent activity against both the key activating mutations and broad coverage of the clinically relevant resistance mutations in KIT-driven GIST.

                          Product Name : IDRX-42

                          Product Type : Small molecule

                          Upfront Cash : Not Applicable

                          November 14, 2024

                          Lead Product(s) : IDRX-42

                          Therapeutic Area : Oncology

                          Highest Development Status : Phase I

                          Sponsor : Not Applicable

                          Deal Size : Not Applicable

                          Deal Type : Not Applicable

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                          03

                          BioAsia
                          Not Confirmed
                          BioAsia
                          Not Confirmed

                          Details : The proceeds will support the ongoing clinical trial of its lead product IDRX-42l, targeting all major categories of activating & resistance mutations in patients with KIT-mutant GIST.

                          Product Name : IDRX-42

                          Product Type : Small molecule

                          Upfront Cash : Undisclosed

                          August 07, 2024

                          Lead Product(s) : IDRX-42

                          Therapeutic Area : Oncology

                          Highest Development Status : Phase I

                          Sponsor : RA Capital Management

                          Deal Size : $120.0 million

                          Deal Type : Series B Financing

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                          04

                          BioAsia
                          Not Confirmed
                          BioAsia
                          Not Confirmed

                          Details : IDRX-42 is a novel, KIT inhibitor that has potent activity against both the key activating mutations and broad coverage of the clinically relevant resistance mutations in KIT-driven GIST.

                          Product Name : IDRX-42

                          Product Type : Small molecule

                          Upfront Cash : Not Applicable

                          June 03, 2024

                          Lead Product(s) : IDRX-42

                          Therapeutic Area : Oncology

                          Highest Development Status : Phase I

                          Sponsor : Not Applicable

                          Deal Size : Not Applicable

                          Deal Type : Not Applicable

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                          05

                          PharmScience R&D
                          Not Confirmed
                          PharmScience R&D
                          Not Confirmed

                          Details : IDRx’s pipeline includes IDRX-42 and IDRX-73, small molecule tyrosine kinase inhibitors acquired through license agreements with Merck KGaA, Darmstadt, Germany, and Blueprint Medicines, respectively.

                          Product Name : IDRX-42

                          Product Type : Small molecule

                          Upfront Cash : Undisclosed

                          August 02, 2022

                          Lead Product(s) : IDRX-42

                          Therapeutic Area : Oncology

                          Highest Development Status : Phase I

                          Sponsor : Andreessen Horowitz

                          Deal Size : $122.0 million

                          Deal Type : Series A Financing

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