Renejix CDMO Partner for Small Molecule Oral Dosage Forms Renejix CDMO Partner for Small Molecule Oral Dosage Forms

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            Details:

            IkT-001Pro is a prodrug formulation of imatinib mesylate and completion of its bioequivalence study of IkT-001Pro compared to 400 mg imatinib mesylate for chronic myelogenous leukemia.

            Lead Product(s): IKT-001PRO

            Therapeutic Area: Oncology Product Name: IkT-001Pro

            Highest Development Status: Phase III Product Type: Small molecule

            Partner/Sponsor/Collaborator: Not Applicable

            Deal Size: Not Applicable Upfront Cash: Not Applicable

            Deal Type: Not Applicable August 17, 2023

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            Details:

            IkT-001Pro is a prodrug formulation of imatinib mesylate and has been developed to improve the safety of the first FDA-approved Abelson kinase inhibitor, imatinib (marketed as Gleevec®), in patients with Chronic Myelogenous Leukemia (CML).

            Lead Product(s): IKT-001PRO

            Therapeutic Area: Oncology Product Name: IkT-001Pro

            Highest Development Status: Phase III Product Type: Small molecule

            Partner/Sponsor/Collaborator: Not Applicable

            Deal Size: Not Applicable Upfront Cash: Not Applicable

            Deal Type: Not Applicable June 22, 2023

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            IkT-001Pro (imatinib mesylate), inhibits abelson (Abl) kinase, the constitutive abnormal tyrosine kinase created by the Philadelphia chromosome abnormality in chronic myeloid leukemia (CML).

            Lead Product(s): IKT-001PRO

            Therapeutic Area: Oncology Product Name: IkT-001Pro

            Highest Development Status: Phase I Product Type: Small molecule

            Partner/Sponsor/Collaborator: Not Applicable

            Deal Size: Not Applicable Upfront Cash: Not Applicable

            Deal Type: Not Applicable March 15, 2023

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            Details:

            IkT-001Pro is a prodrug formulation of imatinib mesylate and has been developed to improve the safety of the first FDA-approved Abelson (Abl) kinase inhibitor, imatinib (marketed as Gleevec®).

            Lead Product(s): IKT-001PRO

            Therapeutic Area: Oncology Product Name: IkT-001Pro

            Highest Development Status: Phase I Product Type: Small molecule

            Partner/Sponsor/Collaborator: Not Applicable

            Deal Size: Not Applicable Upfront Cash: Not Applicable

            Deal Type: Not Applicable December 12, 2022

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            Details:

            In preclinical studies, IkT-001Pro was shown to be as much as 3.4 times safer than imatinib in non-human primates, reducing burdensome gastrointestinal side effects that occur following oral administration.

            Lead Product(s): IKT-001PRO

            Therapeutic Area: Oncology Product Name: IkT-001Pro

            Highest Development Status: IND Enabling Product Type: Small molecule

            Partner/Sponsor/Collaborator: Not Applicable

            Deal Size: Not Applicable Upfront Cash: Not Applicable

            Deal Type: Not Applicable August 26, 2022

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