Year
DEALS // DEV.
Country
Therapeutic Area
Study Phase
Deal Type
Product Type
Dosage Form
Lead Product
Target
Lead Product(s) : Sunobinop
Therapeutic Area : Psychiatry/Psychology
Study Phase : IND Enabling
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Imbrium Submits IND Application to Evaluate Sunobinop for Alcohol Use Disorder
Details : IMB-115 (sunobinop) is designed to bind to and activate the nociceptin/orphanin-FQ peptide receptor (NOP), being investigated for treatment of moderate to severe alcohol use disorder.
Brand Name : IMB-115
Molecule Type : Small molecule
Upfront Cash : Not Applicable
August 05, 2024
Lead Product(s) : Sunobinop
Therapeutic Area : Psychiatry/Psychology
Highest Development Status : IND Enabling
Sponsor : Not Applicable
Deal Size : Not Applicable
Deal Type : Not Applicable
Details : IMB-150 (also known as LYT-503) as a potential non-opioid treatment for female patients with Interstitial Cystitis/Bladder Pain Syndrome (IC/BPS). IMB-150, is a novel formulation of lidocaine, and the clinical development program is called GainMe-IC.
Brand Name : LYT-503
Molecule Type : Large molecule
Upfront Cash : Not Applicable
December 20, 2022
Lead Product(s) : IMB-150
Therapeutic Area : Urology
Study Phase : Preclinical
Recipient : PureTech Health
Deal Size : $59.5 million
Deal Type : Licensing Agreement
Details : Under the terms of the agreement, Imbrium is responsible for all future development activities and funding for LYT-503/IMB-150, for which an IND filing is planned for early 2022.
Brand Name : LYT-503
Molecule Type : Large molecule
Upfront Cash : Undisclosed
August 11, 2021
Lead Product(s) : IMB-150
Therapeutic Area : Urology
Highest Development Status : Preclinical
Recipient : PureTech Health
Deal Size : $59.5 million
Deal Type : Licensing Agreement
Imbrium Therapeutics Presents First Data and Describes Novel Mechanism of Action For IMB-115
Details : IMB-115 is a novel, highly potent and selective partial agonist for nociceptin/orphanin-FQ peptide (NOP) receptors designed to promote sleep onset and maintenance at doses that show minimal or no residual next-day somnolence (drowsiness) or psychomotor i...
Brand Name : IMB-115
Molecule Type : Small molecule
Upfront Cash : Not Applicable
August 28, 2020
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