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    [{"orgOrder":0,"company":"ImCheck Therapeutics","sponsor":"Bpifrance","pharmaFlowCategory":"D","therapeuticArea":"Oncology","country":"FRANCE","productType":"Antibody","year":"2024","type":"Funding","leadProduct":"ICT01","moa":"||BTN3A\/gamma 9-delta 2 T-cell","graph1":"Oncology","graph2":"Phase I\/ Phase II","graph3":"ImCheck Therapeutics","amount2":0,"highestDevelopmentShortName":"Ph I\/II","therapeuticAreaShortName":"Oncology","amount2New":0,"dosageForm":"Intravenous Injection","sponsorNew":"ImCheck Therapeutics \/ Bpifrance","highestDevelopmentStatusID":"7","companyTruncated":"ImCheck Therapeutics \/ Bpifrance"},{"orgOrder":0,"company":"ImCheck Therapeutics","sponsor":"BB Pureos Bioventures","pharmaFlowCategory":"D","therapeuticArea":"Oncology","country":"FRANCE","productType":"Antibody","year":"2020","type":"Series B Financing","leadProduct":"ICT01","moa":"BTN3A\/gamma 9-delta 2 T-cell","graph1":"Oncology","graph2":"Phase I\/ Phase II","graph3":"ImCheck 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Therapeutics","sponsor":"Inapplicable","pharmaFlowCategory":"DU","therapeuticArea":"Oncology","country":"FRANCE","productType":"Antibody","year":"2024","type":"Inapplicable","leadProduct":"Azacitidine","moa":"||BTN3A\/gamma 9-delta 2 T-cell","graph1":"Oncology","graph2":"Phase I\/ Phase II","graph3":"ImCheck Therapeutics","amount2":0,"highestDevelopmentShortName":"Ph I\/II","therapeuticAreaShortName":"Oncology","amount2New":0,"dosageForm":"Undisclosed","sponsorNew":"ImCheck Therapeutics \/ Inapplicable","highestDevelopmentStatusID":"7","companyTruncated":"ImCheck Therapeutics \/ Inapplicable"},{"orgOrder":0,"company":"ImCheck Therapeutics","sponsor":"Inapplicable","pharmaFlowCategory":"DU","therapeuticArea":"Oncology","country":"FRANCE","productType":"Antibody","year":"2021","type":"Inapplicable","leadProduct":"ICT01","moa":"||BTN3A\/gamma 9-delta 2 T-cell","graph1":"Oncology","graph2":"Phase I\/ Phase II","graph3":"ImCheck Therapeutics","amount2":0,"highestDevelopmentShortName":"Ph 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Therapeutics","sponsor":"Inapplicable","pharmaFlowCategory":"DU","therapeuticArea":"Oncology","country":"FRANCE","productType":"Antibody","year":"2020","type":"Inapplicable","leadProduct":"ICT01","moa":"BTN3A\/gamma 9-delta 2 T-cell","graph1":"Oncology","graph2":"Phase I\/ Phase II","graph3":"ImCheck Therapeutics","amount2":0,"highestDevelopmentShortName":"Ph I\/II","therapeuticAreaShortName":"Oncology","amount2New":0,"dosageForm":"Intravenous Injection","sponsorNew":"ImCheck Therapeutics \/ Inapplicable","highestDevelopmentStatusID":"7","companyTruncated":"ImCheck Therapeutics \/ Inapplicable"},{"orgOrder":0,"company":"ImCheck Therapeutics","sponsor":"Inapplicable","pharmaFlowCategory":"DU","therapeuticArea":"Oncology","country":"FRANCE","productType":"Antibody","year":"2020","type":"Inapplicable","leadProduct":"ICT01","moa":"BTN3A\/gamma 9-delta 2 T-cell","graph1":"Oncology","graph2":"Phase I\/ Phase II","graph3":"ImCheck Therapeutics","amount2":0,"highestDevelopmentShortName":"Ph I\/II","therapeuticAreaShortName":"Oncology","amount2New":0,"dosageForm":"Intravenous Injection","sponsorNew":"ImCheck Therapeutics \/ Inapplicable","highestDevelopmentStatusID":"7","companyTruncated":"ImCheck Therapeutics \/ Inapplicable"},{"orgOrder":0,"company":"ImCheck Therapeutics","sponsor":"Synthorx","pharmaFlowCategory":"DU","therapeuticArea":"Oncology","country":"FRANCE","productType":"Protein","year":"2021","type":"Inapplicable","leadProduct":"THOR-707","moa":"||Non-alpha IL-2","graph1":"Oncology","graph2":"Phase I\/ Phase II","graph3":"ImCheck Therapeutics","amount2":0,"highestDevelopmentShortName":"Ph I\/II","therapeuticAreaShortName":"Oncology","amount2New":0,"dosageForm":"Intravenous Infusion","sponsorNew":"ImCheck Therapeutics \/ Synthorx","highestDevelopmentStatusID":"7","companyTruncated":"ImCheck Therapeutics \/ Synthorx"}]

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                            01

                            ImCheck Therapeutics

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                            Lead Product(s) : ICT01,Azacitidine

                            Therapeutic Area : Oncology

                            Study Phase : Phase I/ Phase II

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

                            DEALS_DEV arrow-down

                            ImCheck's ICT01 Receives FDA Fast Track for AML Combo Treatment

                            Details : ImCheck receives fDA fast track designation for ICT01 in Combination with Azacitidine and Venetoclax in first-line acute myeloid leukemia for patients unfit for induction chemotherapy treatment.

                            Product Name : ICT01

                            Product Type : Antibody

                            Upfront Cash : Inapplicable

                            September 18, 2024

                            Lead Product(s) : ICT01,Azacitidine

                            Therapeutic Area : Oncology

                            Highest Development Status : Phase I/ Phase II

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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                            02

                            ImCheck Therapeutics

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                            Lead Product(s) : ICT01,Pembrolizumab

                            Therapeutic Area : Oncology

                            Study Phase : Phase I/ Phase II

                            Sponsor : Bpifrance

                            Deal Size : $22.4 million

                            Deal Type : Funding

                            DEALS_DEV arrow-down

                            ImCheck Receives €20.18M from French Government For Drug Development

                            Details : The funding will support company’s ICT01, a pathogen-agnostic γ9δ2 T cell-activating monoclonal antibody, currently in a Phase I/IIa in various solid cancer and hematologic malignancy indications.

                            Product Name : ICT01

                            Product Type : Antibody

                            Upfront Cash : Undisclosed

                            August 29, 2024

                            Lead Product(s) : ICT01,Pembrolizumab

                            Therapeutic Area : Oncology

                            Highest Development Status : Phase I/ Phase II

                            Sponsor : Bpifrance

                            Deal Size : $22.4 million

                            Deal Type : Funding

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                            03

                            ImCheck Therapeutics

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                            Peptide Therapy Summit
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                            Lead Product(s) : ICT01

                            Therapeutic Area : Oncology

                            Study Phase : Phase I/ Phase II

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

                            DEALS_DEV arrow-down

                            ImCheck Presents Initial Patient Data from the EVICTION-2 Clinical Trial at SITC Annual Meeting

                            Details : The combination also demonstrated the activation, mobilization, and proliferation of CD8 T cells and NKs, with slightly more modest effects on granulocytes, in most patients at lower ICT01 doses than shown in previously presented data of ICT01 monotherap...

                            Product Name : ICT01

                            Product Type : Antibody

                            Upfront Cash : Inapplicable

                            November 11, 2022

                            Lead Product(s) : ICT01

                            Therapeutic Area : Oncology

                            Highest Development Status : Phase I/ Phase II

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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                            04

                            ImCheck Therapeutics

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                            Peptide Therapy Summit
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                            Lead Product(s) : ICT01,Pembrolizumab

                            Therapeutic Area : Oncology

                            Study Phase : Phase I/ Phase II

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

                            DEALS_DEV arrow-down

                            ImCheck Presents Positive Safety and Efficacy Data from the Completed Phase 1 Dose Escalation Cohort of ICT01 ...

                            Details : Broad antitumor immune responses and demonstration of durable disease control from solid tumor patients who previously failed one or more checkpoint-inhibitor regimen, across a range of ICT01 doses in combination with pembrolizumab.

                            Product Name : ICT01

                            Product Type : Antibody

                            Upfront Cash : Inapplicable

                            October 09, 2022

                            Lead Product(s) : ICT01,Pembrolizumab

                            Therapeutic Area : Oncology

                            Highest Development Status : Phase I/ Phase II

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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                            05

                            ImCheck Therapeutics

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                            Peptide Therapy Summit
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                            ImCheck Therapeutics

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                            Lead Product(s) : ICT01,Pembrolizumab

                            Therapeutic Area : Oncology

                            Study Phase : Phase I/ Phase II

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

                            DEALS_DEV arrow-down

                            ImCheck Provides Updated ICT01 and Pembrolizumab Combination Data from the Phase I/IIa EVICTION Trial at AACR ...

                            Details : Clinical responses achieved with low doses of ICT01 in combination with pembrolizumab in solid tumor patients who previously failed checkpoint-inhibitor therapy support the complementary mechanisms of action with potential for anti-tumor activity.

                            Product Name : ICT01

                            Product Type : Antibody

                            Upfront Cash : Inapplicable

                            August 04, 2022

                            Lead Product(s) : ICT01,Pembrolizumab

                            Therapeutic Area : Oncology

                            Highest Development Status : Phase I/ Phase II

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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                            06

                            ImCheck Therapeutics

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                            Lead Product(s) : ICT01,Pembrolizumab

                            Therapeutic Area : Oncology

                            Study Phase : Phase I/ Phase II

                            Sponsor : Earlybird

                            Deal Size : $103.0 million

                            Deal Type : Series C Financing

                            DEALS_DEV arrow-down

                            ImCheck Closes Upsized EUR 96 Million (USD 103 Million) Financing to Advance Clinical Program of First-in-huma...

                            Details : The proceeds will be used to support the Phase IIa expansion arms of EVICTION in solid tumors and hematologic cancers, and completion of placebo-controlled clinical trials evaluating ImCheck’s lead candidate ICT01 in combination with a PD-1 inhibitor f...

                            Product Name : ICT01

                            Product Type : Antibody

                            Upfront Cash : Undisclosed

                            June 13, 2022

                            Lead Product(s) : ICT01,Pembrolizumab

                            Therapeutic Area : Oncology

                            Highest Development Status : Phase I/ Phase II

                            Sponsor : Earlybird

                            Deal Size : $103.0 million

                            Deal Type : Series C Financing

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                            07

                            ImCheck Therapeutics

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                            Lead Product(s) : ICT01,Pembrolizumab

                            Therapeutic Area : Oncology

                            Study Phase : Phase I

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

                            DEALS_DEV arrow-down

                            ImCheck Provides Promising Updated Patient Response Data from the Phase I/IIa EVICTION Trial with ICT01 at SIT...

                            Details : Presented results demonstrating ICT01 plus pembrolizumab induced anti-tumor responses in patients with a range of solid tumors. 5 of 8 patients achieved disease control at 8 weeks and beyond according to RECIST1.1, including two partial responses at week...

                            Product Name : ICT01

                            Product Type : Antibody

                            Upfront Cash : Inapplicable

                            December 11, 2021

                            Lead Product(s) : ICT01,Pembrolizumab

                            Therapeutic Area : Oncology

                            Highest Development Status : Phase I

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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                            08

                            ImCheck Therapeutics

                            France arrow
                            Peptide Therapy Summit
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                            ImCheck Therapeutics

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                            Lead Product(s) : ICT01,Pembrolizumab

                            Therapeutic Area : Oncology

                            Study Phase : Phase I

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

                            DEALS_DEV arrow-down

                            ImCheck Publishes Comprehensive Overview of the Development Results of Its First-in-class Cancer Immunotherape...

                            Details : CT01 is a fully-humanized anti-BTN3A monoclonal antibody designed to selectively activate gamma 9 delta 2 (Vγ9Vδ2) T cells through all three isoforms of BTN3A (1/2/3). CT01 has been shown to have anti-tumor activity against a range of cancers.

                            Product Name : ICT01

                            Product Type : Antibody

                            Upfront Cash : Inapplicable

                            October 20, 2021

                            Lead Product(s) : ICT01,Pembrolizumab

                            Therapeutic Area : Oncology

                            Highest Development Status : Phase I

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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                            09

                            ImCheck Therapeutics

                            France arrow
                            Peptide Therapy Summit
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                            ImCheck Therapeutics

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                            Lead Product(s) : ICT01,Pembrolizumab

                            Therapeutic Area : Oncology

                            Study Phase : Phase I

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

                            DEALS_DEV arrow-down

                            ImCheck Presents Preliminary Patient Response Data from the Phase I/IIa EVICTION Trial with ICT01 at ESMO Cong...

                            Details : ICT01 is a humanized, anti-BTN3A (CD277) monoclonal antibody that selectively activates γ9δ2 T cells. Monotherapy and combination of ICT01 and pembrolizumab, showed antitumor immune response against bladder cancer, metastatic melanoma and non-small cel...

                            Product Name : ICT01

                            Product Type : Antibody

                            Upfront Cash : Inapplicable

                            September 17, 2021

                            Lead Product(s) : ICT01,Pembrolizumab

                            Therapeutic Area : Oncology

                            Highest Development Status : Phase I

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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                            10

                            ImCheck Therapeutics

                            France arrow
                            Peptide Therapy Summit
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                            ImCheck Therapeutics

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                            Lead Product(s) : ICT01,Pembrolizumab

                            Therapeutic Area : Oncology

                            Study Phase : Phase I

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

                            DEALS_DEV arrow-down

                            Clinical Data with ImCheck’s ICT01 to be Presented at AACR

                            Details : ICT01 activates γ9δ2 T cells that rapidly migrate out of the circulation and secrete IFNγ and TNFα leading to an expanded immune system activation.

                            Product Name : ICT01

                            Product Type : Antibody

                            Upfront Cash : Inapplicable

                            September 04, 2021

                            Lead Product(s) : ICT01,Pembrolizumab

                            Therapeutic Area : Oncology

                            Highest Development Status : Phase I

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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