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                          Therapeutic Area by Lead Product

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                          Top Deals by Deal Size (USD bn)

                          01

                          Pharma, Lab & Chemical Expo
                          Not Confirmed
                          Pharma, Lab & Chemical Expo
                          Not Confirmed

                          Details : IMM01-STEM, a secretome product derived from partially differentiated pluripotent stem cells that contains regenerative molecules, being investigated for muscle atrophy related to knee osteoarthritis.

                          Brand Name : IMM01-STEM

                          Molecule Type : Cell and Gene therapy

                          Upfront Cash : Not Applicable

                          November 19, 2024

                          Lead Product(s) : IMM01-STEM

                          Therapeutic Area : Musculoskeletal

                          Highest Development Status : Phase I/ Phase II

                          Sponsor : Not Applicable

                          Deal Size : Not Applicable

                          Deal Type : Not Applicable

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                          02

                          Pharma, Lab & Chemical Expo
                          Not Confirmed
                          Pharma, Lab & Chemical Expo
                          Not Confirmed

                          Details : IMM01-STEM, a secretome product derived from partially differentiated pluripotent stem cells that contains regenerative molecules, being investigated for sarcopenic obesity.

                          Brand Name : IMM01-STEM

                          Molecule Type : Cell and Gene therapy

                          Upfront Cash : Not Applicable

                          September 10, 2024

                          Lead Product(s) : IMM01-STEM

                          Therapeutic Area : Nutrition and Weight Loss

                          Highest Development Status : Phase I

                          Sponsor : Not Applicable

                          Deal Size : Not Applicable

                          Deal Type : Not Applicable

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                          03

                          Pharma, Lab & Chemical Expo
                          Not Confirmed
                          Pharma, Lab & Chemical Expo
                          Not Confirmed

                          Details : Immunis partners with Springbok to evaluate the efficacy of its investigational secretome therapeutic, IMM01-STEM in restoring muscle growth and function in a sarcopenic.

                          Brand Name : IMM01-STEM

                          Molecule Type : Cell and Gene therapy

                          Upfront Cash : Undisclosed

                          July 25, 2024

                          Lead Product(s) : IMM01-STEM

                          Therapeutic Area : Musculoskeletal

                          Highest Development Status : Phase I/ Phase II

                          Sponsor : Springbok

                          Deal Size : Undisclosed

                          Deal Type : Partnership

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                          04

                          Pharma, Lab & Chemical Expo
                          Not Confirmed
                          Pharma, Lab & Chemical Expo
                          Not Confirmed

                          Details : The partnership aims to focus on the clinical development of TRK-820 (nalfurafine hydrochloride), which is being evaluated for the treatment of Uremic Pruritus.

                          Brand Name : TRK-820

                          Molecule Type : Small molecule

                          Upfront Cash : Undisclosed

                          May 22, 2024

                          Lead Product(s) : Nalfurafine

                          Therapeutic Area : Dermatology

                          Highest Development Status : Phase I

                          Recipient : Toray Industries

                          Deal Size : Undisclosed

                          Deal Type : Partnership

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                          05

                          Pharma, Lab & Chemical Expo
                          Not Confirmed
                          Pharma, Lab & Chemical Expo
                          Not Confirmed

                          Details : IMMUNA (IMM01-STEM) is a secretome product derived from partially differentiated pluripotent stem cells that contains regenerative molecules, which is investigated for the treatment of Muscle Atrophy.

                          Brand Name : IMMUNA

                          Molecule Type : Cell and Gene therapy

                          Upfront Cash : Not Applicable

                          August 01, 2023

                          Lead Product(s) : IMM01-STEM

                          Therapeutic Area : Musculoskeletal

                          Highest Development Status : Phase I/ Phase II

                          Sponsor : Not Applicable

                          Deal Size : Not Applicable

                          Deal Type : Not Applicable

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                          06

                          Pharma, Lab & Chemical Expo
                          Not Confirmed
                          Pharma, Lab & Chemical Expo
                          Not Confirmed

                          Details : IMM01-STEM, a secretome product derived from partially differentiated pluripotent stem cells that contains regenerative molecules, in participants with muscle atrophy related to knee osteoarthritis (KOA).

                          Brand Name : IMM01-STEM

                          Molecule Type : Cell and Gene therapy

                          Upfront Cash : Not Applicable

                          January 24, 2023

                          Lead Product(s) : IMM01-STEM

                          Therapeutic Area : Musculoskeletal

                          Highest Development Status : Phase I/ Phase II

                          Sponsor : Not Applicable

                          Deal Size : Not Applicable

                          Deal Type : Not Applicable

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