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                          Details : CD19 t-haNK is a human, allogeneic, NK cell line that has been engineered to express a CAR targeting CD19, which is being evaluated for the treatment of refractory/ relapsed non-hodgkin lymphoma.

                          Brand Name : CD19 t-haNK

                          Molecule Type : Cell and Gene therapy

                          Upfront Cash : Not Applicable

                          October 24, 2024

                          Lead Product(s) : CD19 t-haNK,Rituximab

                          Therapeutic Area : Oncology

                          Highest Development Status : Phase I

                          Sponsor : Not Applicable

                          Deal Size : Not Applicable

                          Deal Type : Not Applicable

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                          02

                          Pharmtech & Ingredients
                          Not Confirmed
                          Pharmtech & Ingredients
                          Not Confirmed

                          Details : Anktiva (nogapendekin alfa inbakicept-pmln) is a IL-15 receptor agonist, which is being evaluated in combination with AdHER2DC vaccine for the treatment of endometrial cancer.

                          Brand Name : Anktiva

                          Molecule Type : Large molecule

                          Upfront Cash : Not Applicable

                          August 06, 2024

                          Lead Product(s) : Nogapendekin Alfa Inbakicept,AdHER2DC,Pembrolizumab

                          Therapeutic Area : Oncology

                          Highest Development Status : Phase I/ Phase II

                          Sponsor : Not Applicable

                          Deal Size : Not Applicable

                          Deal Type : Not Applicable

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                          03

                          Pharmtech & Ingredients
                          Not Confirmed
                          Pharmtech & Ingredients
                          Not Confirmed

                          Details : With the termination, LadRx regains control of INNO-206 (aldoxorubicin), a rationally-engineered cytotoxic which delivers well-established anti-cancer agent, doxorubicin, into the tumor.

                          Brand Name : INNO-206

                          Molecule Type : Small molecule

                          Upfront Cash : Undisclosed

                          June 03, 2024

                          Lead Product(s) : Aldoxorubicin

                          Therapeutic Area : Oncology

                          Highest Development Status : Phase III

                          Recipient : LadRx

                          Deal Size : $356.0 million

                          Deal Type : Termination

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                          04

                          Pharmtech & Ingredients
                          Not Confirmed
                          Pharmtech & Ingredients
                          Not Confirmed

                          Details : Through the agreement, the companies will concentrate on scaling up the manufacture of BCG for use in combination with Anktiva (Nogapendekin Alfa Inbakicept) for non-muscle invasive bladder cancer.

                          Brand Name : Anktiva

                          Molecule Type : Large molecule

                          Upfront Cash : Undisclosed

                          May 02, 2024

                          Lead Product(s) : Nogapendekin Alfa Inbakicept,Recombinant Bacillus Calmette-Guerin

                          Therapeutic Area : Oncology

                          Highest Development Status : IND Enabling

                          Sponsor : Serum Institute of India

                          Deal Size : Undisclosed

                          Deal Type : Agreement

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                          05

                          Pharmtech & Ingredients
                          Not Confirmed
                          Pharmtech & Ingredients
                          Not Confirmed

                          Details : Anktiva™ (N-803 ), a lead cytokine fusion protein, is a novel IL-15 superagonist complex and which is investigated for advanced non-small cell lung cancer.

                          Brand Name : Anktiva

                          Molecule Type : Large molecule

                          Upfront Cash : Not Applicable

                          April 25, 2024

                          Lead Product(s) : Nogapendekin Alfa Inbakicept,Pembrolizumab

                          Therapeutic Area : Oncology

                          Highest Development Status : Phase II

                          Sponsor : Not Applicable

                          Deal Size : Not Applicable

                          Deal Type : Not Applicable

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                          06

                          Pharmtech & Ingredients
                          Not Confirmed
                          Pharmtech & Ingredients
                          Not Confirmed

                          Details : Anktiva (nogapendekin alfa inbakicept-pmln) is an IL-15 receptor agonist, evaluated with Bacillus Calmette-Guérin (BCG) for BCG-unresponsive non-muscle invasive bladder cancer treatment.

                          Brand Name : Anktiva

                          Molecule Type : Large molecule

                          Upfront Cash : Not Applicable

                          April 22, 2024

                          Lead Product(s) : Nogapendekin Alfa Inbakicept,BCG Vaccine

                          Therapeutic Area : Oncology

                          Highest Development Status : Approved

                          Sponsor : Not Applicable

                          Deal Size : Not Applicable

                          Deal Type : Not Applicable

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                          07

                          Pharmtech & Ingredients
                          Not Confirmed
                          Pharmtech & Ingredients
                          Not Confirmed

                          Lead Product(s) : Ad5 CEA/MUC1/Brachyury Vaccine Tri-Ad5,Nogapendekin Alfa

                          Therapeutic Area : Oncology

                          Study Phase : Phase II

                          Sponsor : Not Applicable

                          Deal Size : Not Applicable

                          Deal Type : Not Applicable

                          Details : Tri-Ad5 vaccine combination (hAd5 CEA/MUC1/brachyury) together with its IL-15 superagonist and immune enhancer N-803 is being evaluated in people with Lynch syndrome.

                          Brand Name : Tri Ad5

                          Molecule Type : Vaccine

                          Upfront Cash : Not Applicable

                          February 21, 2024

                          Lead Product(s) : Ad5 CEA/MUC1/Brachyury Vaccine Tri-Ad5,Nogapendekin Alfa

                          Therapeutic Area : Oncology

                          Highest Development Status : Phase II

                          Sponsor : Not Applicable

                          Deal Size : Not Applicable

                          Deal Type : Not Applicable

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                          08

                          Pharmtech & Ingredients
                          Not Confirmed
                          Pharmtech & Ingredients
                          Not Confirmed

                          Details : Proceeds will also support N-803 (Anktiva), an interleukin-15 superagonist fusion protein, currently in clinical trials for solid tumors including BCG-unresponsive non-muscle invasive bladder cancer.

                          Brand Name : Anktiva

                          Molecule Type : Large molecule

                          Upfront Cash : Undisclosed

                          January 02, 2024

                          Lead Product(s) : N-803,BCG Vaccine

                          Therapeutic Area : Oncology

                          Highest Development Status : Phase II/ Phase III

                          Sponsor : Oberland Capital

                          Deal Size : $320.0 million

                          Deal Type : Financing

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                          09

                          Pharmtech & Ingredients
                          Not Confirmed
                          Pharmtech & Ingredients
                          Not Confirmed

                          Details : Anktiva (N-803 ), a lead cytokine fusion protein, is a novel IL-15 superagonist complex plus Bacillus Calmette-Guérin (BCG) for the treatment of BCG-unresponsive non-muscle-invasive bladder cancer carcinoma in situ (CIS) with or without Ta or T1 disease...

                          Brand Name : Anktiva

                          Molecule Type : Large molecule

                          Upfront Cash : Not Applicable

                          October 26, 2023

                          Lead Product(s) : N-803,BCG Vaccine

                          Therapeutic Area : Oncology

                          Highest Development Status : Phase II/ Phase III

                          Sponsor : Not Applicable

                          Deal Size : Not Applicable

                          Deal Type : Not Applicable

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                          10

                          Pharmtech & Ingredients
                          Not Confirmed
                          Pharmtech & Ingredients
                          Not Confirmed

                          Details : Anktiva (N-803 ), a lead cytokine fusion protein, is a novel IL-15 superagonist complex plus Bacillus Calmette-Guérin (BCG) for the treatment of BCG-unresponsive non-muscle-invasive bladder cancer carcinoma in situ (CIS) with or without Ta or T1 disease...

                          Brand Name : Anktiva

                          Molecule Type : Large molecule

                          Upfront Cash : Not Applicable

                          October 23, 2023

                          Lead Product(s) : N-803,BCG Vaccine

                          Therapeutic Area : Oncology

                          Highest Development Status : Phase II/ Phase III

                          Sponsor : Not Applicable

                          Deal Size : Not Applicable

                          Deal Type : Not Applicable

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