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                          Top Deals by Deal Size (USD bn)

                          01

                          Peptide Therapy Summit
                          Not Confirmed
                          Peptide Therapy Summit
                          Not Confirmed

                          Details : Aqilion resumes TAK1 program for inflammation after regaining rights. targeting chronic inflammation such as autoimmune diseases.

                          Product Name : Undisclosed

                          Product Type : Other Small Molecule

                          Upfront Cash : Inapplicable

                          February 05, 2025

                          Lead Product(s) : Undisclosed

                          Therapeutic Area : Immunology

                          Highest Development Status : Discovery

                          Sponsor : Inapplicable

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

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                          02

                          Peptide Therapy Summit
                          Not Confirmed
                          Peptide Therapy Summit
                          Not Confirmed

                          Details :

                          Product Name : Undisclosed

                          Product Type : Antibody

                          Upfront Cash : Undisclosed

                          December 16, 2024

                          Lead Product(s) : Undisclosed

                          Therapeutic Area : Immunology

                          Highest Development Status : Discovery

                          Sponsor : Candid Therapeutics

                          Deal Size : $1,000.0 million

                          Deal Type : Collaboration

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                          03

                          Peptide Therapy Summit
                          Not Confirmed
                          Peptide Therapy Summit
                          Not Confirmed

                          Details : The companies entered a strategic research collaboration to discover and develop novel T Cell Engager program candidates for various autoimmune indications.

                          Product Name : Undisclosed

                          Product Type : Undisclosed

                          Upfront Cash : Undisclosed

                          December 16, 2024

                          Lead Product(s) : Undisclosed

                          Therapeutic Area : Immunology

                          Highest Development Status : Discovery

                          Sponsor : Candid Therapeutics

                          Deal Size : Undisclosed

                          Deal Type : Collaboration

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                          04

                          Peptide Therapy Summit
                          Not Confirmed
                          Peptide Therapy Summit
                          Not Confirmed

                          Details : The agreement aims to advance development of therapeutics for allergy relief, mutating infectious diseases and antimicrobial resistance with Mayo Clinic’s research infrastructure.

                          Product Name : Undisclosed

                          Product Type : Undisclosed

                          Upfront Cash : Undisclosed

                          December 06, 2024

                          Lead Product(s) : Undisclosed

                          Therapeutic Area : Immunology

                          Highest Development Status : Discovery

                          Sponsor : Mayo Clinic

                          Deal Size : Undisclosed

                          Deal Type : Agreement

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                          05

                          Peptide Therapy Summit
                          Not Confirmed
                          Peptide Therapy Summit
                          Not Confirmed

                          Details : Mirador will leverage a set of deidentified genetic and phenotypic data from the 23andMe's proprietary Mirador360 development engine to enable target validation and precision medicine.

                          Product Name : Undisclosed

                          Product Type : Undisclosed

                          Upfront Cash : Undisclosed

                          November 20, 2024

                          Lead Product(s) : Undisclosed

                          Therapeutic Area : Immunology

                          Highest Development Status : Discovery

                          Sponsor : Mirador Therapeutics

                          Deal Size : Undisclosed

                          Deal Type : Collaboration

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                          06

                          Peptide Therapy Summit
                          Not Confirmed
                          Peptide Therapy Summit
                          Not Confirmed

                          Details : The net proceeds will be used to further develop DeepCure’s cutting-edge technology for small molecule drug discovery, and to advance its immunology and inflammation pipeline towards clinical trials.

                          Product Name : Brd4

                          Product Type : Other Small Molecule

                          Upfront Cash : Undisclosed

                          November 04, 2024

                          Lead Product(s) : Brd4

                          Therapeutic Area : Immunology

                          Highest Development Status : Discovery

                          Sponsor : IAG Capital Partners

                          Deal Size : $24.6 million

                          Deal Type : Series A Financing

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                          07

                          Peptide Therapy Summit
                          Not Confirmed
                          Peptide Therapy Summit
                          Not Confirmed

                          Details : Nurix and Sanofi have agreed to extend the research period for the ongoing STAT6 degrader program, aimed at developing candidates for treating inflammation and autoimmune diseases.

                          Product Name : Undisclosed

                          Product Type : Undisclosed

                          Upfront Cash : $55.0 million

                          September 04, 2024

                          Lead Product(s) : Undisclosed

                          Therapeutic Area : Immunology

                          Highest Development Status : Discovery

                          Sponsor : Sanofi

                          Deal Size : $2,577.0 million

                          Deal Type : Expanded Collaboration

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                          08

                          Peptide Therapy Summit
                          Not Confirmed
                          Peptide Therapy Summit
                          Not Confirmed

                          Details : The Company intends to use the proceeds to accelerate the development of its platform and advance novel therapies for autoimmune diseases.

                          Product Name : Undisclosed

                          Product Type : Undisclosed

                          Upfront Cash : Undisclosed

                          August 29, 2024

                          Lead Product(s) : Undisclosed

                          Therapeutic Area : Immunology

                          Highest Development Status : Discovery

                          Sponsor : National Institutes of Health

                          Deal Size : $2.0 million

                          Deal Type : Funding

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                          09

                          Peptide Therapy Summit
                          Not Confirmed
                          Peptide Therapy Summit
                          Not Confirmed

                          Details :

                          Product Name : Undisclosed

                          Product Type : Undisclosed

                          Upfront Cash : Undisclosed

                          July 31, 2024

                          Lead Product(s) : Undisclosed

                          Therapeutic Area : Immunology

                          Highest Development Status : Discovery

                          Sponsor : Eli Lilly

                          Deal Size : Undisclosed

                          Deal Type : Expanded Collaboration

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                          10

                          Peptide Therapy Summit
                          Not Confirmed
                          Peptide Therapy Summit
                          Not Confirmed

                          Details : The partnership aims to develop new generational & multi-specific antibodies to address the treatment of autoimmune diseases such as SLE and drive significant progress in the self-immune drug market.

                          Product Name : Undisclosed

                          Product Type : Undisclosed

                          Upfront Cash : Undisclosed

                          July 31, 2024

                          Lead Product(s) : Undisclosed

                          Therapeutic Area : Immunology

                          Highest Development Status : Discovery

                          Sponsor : A STAR

                          Deal Size : Undisclosed

                          Deal Type : Partnership

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