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Therapeutics","sponsor":"Inapplicable","pharmaFlowCategory":"DU","therapeuticArea":"Immunology","country":"UNITED KINGDOM","productType":"Cell and Gene therapy","year":"2021","type":"Inapplicable","leadProduct":"QEL-001","moa":"Undisclosed","graph1":"Immunology","graph2":"IND Enabling","graph3":"Quell Therapeutics","amount2":0,"highestDevelopmentShortName":"IND","therapeuticAreaShortName":"Immunology","amount2New":0,"dosageForm":"Undisclosed","sponsorNew":"Quell Therapeutics \/ Inapplicable","highestDevelopmentStatusID":"5","companyTruncated":"Quell Therapeutics \/ Inapplicable"}]

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                          01

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                          Details : S‑8484 is an engineered IgE protease works by rapid and sustained degradation of IgE in plasma and on IgE B cell receptors. It is being investigated for allergic disease.

                          Product Name : S‑8484

                          Product Type : Enzyme

                          Upfront Cash : Inapplicable

                          February 28, 2025

                          Lead Product(s) : S‑8484

                          Therapeutic Area : Immunology

                          Highest Development Status : IND Enabling

                          Sponsor : Inapplicable

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

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                          02

                          AAN
                          Not Confirmed
                          AAN
                          Not Confirmed

                          Details : UC101 is the world’s first FDA IND-approved umbilical cord blood-derived allogeneic CAR-T therapy. It is being evaluated to alleviate the risk of host-versus-graft response.

                          Product Name : UC101

                          Product Type : Cell and Gene therapy

                          Upfront Cash : Inapplicable

                          January 29, 2025

                          Lead Product(s) : UC101

                          Therapeutic Area : Immunology

                          Highest Development Status : IND Enabling

                          Sponsor : VectorBuilder

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

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                          03

                          AAN
                          Not Confirmed
                          AAN
                          Not Confirmed

                          Details : FDA has cleared its Investigational New Drug (IND) application for a rheumatology basket study of ALLO-329, an investigational allogeneic CAR T product for autoimmune diseases.

                          Product Name : ALLO-329

                          Product Type : Cell and Gene therapy

                          Upfront Cash : Inapplicable

                          January 28, 2025

                          Lead Product(s) : ALLO-329

                          Therapeutic Area : Immunology

                          Highest Development Status : IND Enabling

                          Sponsor : Inapplicable

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

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                          04

                          AAN
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                          AAN
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                          Details : SJP-001 is a combination of two OTC oral generic drugs (i.e., a NSAID (naproxen) and an H1-antagonist (fexofenadine), being investigated for inflammatory and metabolic health disorders.

                          Product Name : SJP-001

                          Product Type : Other Small Molecule

                          Upfront Cash : Inapplicable

                          January 14, 2025

                          Lead Product(s) : Naproxen,Fexofenadine Hydrochloride

                          Therapeutic Area : Immunology

                          Highest Development Status : IND Enabling

                          Sponsor : Inapplicable

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

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                          05

                          AAN
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                          Details :

                          Product Name : CT103A

                          Product Type : Cell and Gene therapy

                          Upfront Cash : Inapplicable

                          December 08, 2024

                          Lead Product(s) : Equecabtagene Autoleucel

                          Therapeutic Area : Immunology

                          Highest Development Status : IND Enabling

                          Sponsor : Inapplicable

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

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                          06

                          AAN
                          Not Confirmed
                          AAN
                          Not Confirmed

                          Details : Under the agreement, Allogene will use Arbor’s proprietary CRISPR gene-editing technology in its next generation AlloCAR T platform, ALLO-329, for the treatment of autoimmune disease (AID).

                          Product Name : ALLO-329

                          Product Type : Cell and Gene therapy

                          Upfront Cash : Undisclosed

                          December 03, 2024

                          Lead Product(s) : ALLO-329

                          Therapeutic Area : Immunology

                          Highest Development Status : IND Enabling

                          Sponsor : Allogene Therapeutics

                          Deal Size : Undisclosed

                          Deal Type : Licensing Agreement

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                          07

                          AAN
                          Not Confirmed
                          AAN
                          Not Confirmed

                          Details :

                          Product Name : LP-003

                          Product Type : Other Large Molecule

                          Upfront Cash : Inapplicable

                          November 25, 2024

                          Lead Product(s) : LP-003

                          Therapeutic Area : Immunology

                          Highest Development Status : IND Enabling

                          Sponsor : Inapplicable

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

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                          08

                          AAN
                          Not Confirmed
                          AAN
                          Not Confirmed

                          Details : IMSB301 is a novel, orally available small molecule cGAS inhibitor drug candidate, that is being developed for the treatment of Aicardi Goutières Syndrome.

                          Product Name : IMSB301

                          Product Type : Other Small Molecule

                          Upfront Cash : Inapplicable

                          November 20, 2024

                          Lead Product(s) : IMSB301

                          Therapeutic Area : Immunology

                          Highest Development Status : IND Enabling

                          Sponsor : Inapplicable

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

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                          09

                          AAN
                          Not Confirmed
                          AAN
                          Not Confirmed

                          Details : ACE1831 is a CD20 inhibitor cell and gene therapy candidate, which is currently being evaluated for the treatment of IgG4-related disease.

                          Product Name : ACE1831

                          Product Type : Cell and Gene therapy

                          Upfront Cash : Inapplicable

                          November 15, 2024

                          Lead Product(s) : ACE1831

                          Therapeutic Area : Immunology

                          Highest Development Status : IND Enabling

                          Sponsor : Inapplicable

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

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                          10

                          AAN
                          Not Confirmed
                          AAN
                          Not Confirmed

                          Details : CID-103 is a fully human IgG1 anti-CD38 monoclonal antibody, which is currently being evaluated for the treatment of chronic immune thrombocytopenia in adults.

                          Product Name : CID-103

                          Product Type : Antibody

                          Upfront Cash : Inapplicable

                          October 24, 2024

                          Lead Product(s) : CID-103

                          Therapeutic Area : Immunology

                          Highest Development Status : IND Enabling

                          Sponsor : Inapplicable

                          Deal Size : Inapplicable

                          Deal Type : Inapplicable

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