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I","therapeuticAreaShortName":"Immunology","amount2New":0,"dosageForm":"Nasal Spray","sponsorNew":"Revelation Biosciences \/ Inapplicable","highestDevelopmentStatusID":"6","companyTruncated":"Revelation Biosciences \/ Inapplicable"},{"orgOrder":0,"company":"Revelation Biosciences","sponsor":"Roth Capital Partners","pharmaFlowCategory":"D","therapeuticArea":"Immunology","country":"U.S.A","productType":"Other Small Molecule","year":"2022","type":"Public Offering","leadProduct":"REVTx-99b","moa":"CCR3","graph1":"Immunology","graph2":"Phase I","graph3":"Revelation Biosciences","amount2":0,"highestDevelopmentShortName":"Ph I","therapeuticAreaShortName":"Immunology","amount2New":0,"dosageForm":"Nasal Spray","sponsorNew":"Revelation Biosciences \/ Roth Capital Partners","highestDevelopmentStatusID":"6","companyTruncated":"Revelation Biosciences \/ Roth Capital Partners"},{"orgOrder":0,"company":"Revelation Biosciences","sponsor":"Roth Capital Partners","pharmaFlowCategory":"D","therapeuticArea":"Immunology","country":"U.S.A","productType":"Other Small Molecule","year":"2022","type":"Public Offering","leadProduct":"REVTx-99b","moa":"CCR3","graph1":"Immunology","graph2":"Phase I","graph3":"Revelation Biosciences","amount2":0,"highestDevelopmentShortName":"Ph I","therapeuticAreaShortName":"Immunology","amount2New":0,"dosageForm":"Nasal Spray","sponsorNew":"Revelation Biosciences \/ Roth Capital Partners","highestDevelopmentStatusID":"6","companyTruncated":"Revelation Biosciences \/ Roth Capital Partners"},{"orgOrder":0,"company":"Orexo","sponsor":"Inapplicable","pharmaFlowCategory":"DU","therapeuticArea":"Immunology","country":"SWEDEN","productType":"Hormone","year":"2024","type":"Inapplicable","leadProduct":"Epinephrine","moa":"Adrenergic receptor","graph1":"Immunology","graph2":"Phase I","graph3":"Orexo","amount2":0,"highestDevelopmentShortName":"Ph 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I","graph3":"Prometheus Biosciences","amount2":0,"highestDevelopmentShortName":"Ph I","therapeuticAreaShortName":"Immunology","amount2New":0,"dosageForm":"Intravenous Injection","sponsorNew":"Prometheus Biosciences \/ Inapplicable","highestDevelopmentStatusID":"6","companyTruncated":"Prometheus Biosciences \/ Inapplicable"},{"orgOrder":0,"company":"AnaMar","sponsor":"Inapplicable","pharmaFlowCategory":"DU","therapeuticArea":"Immunology","country":"SWEDEN","productType":"Other Small Molecule","year":"2024","type":"Inapplicable","leadProduct":"AM1476","moa":"5-HT2B receptor","graph1":"Immunology","graph2":"Phase I","graph3":"AnaMar","amount2":0,"highestDevelopmentShortName":"Ph I","therapeuticAreaShortName":"Immunology","amount2New":0,"dosageForm":"Oral Capsule","sponsorNew":"AnaMar \/ Inapplicable","highestDevelopmentStatusID":"6","companyTruncated":"AnaMar \/ Inapplicable"},{"orgOrder":0,"company":"AnaMar","sponsor":"Inapplicable","pharmaFlowCategory":"DU","therapeuticArea":"Immunology","country":"SWEDEN","productType":"Other Small Molecule","year":"2023","type":"Inapplicable","leadProduct":"AM1476","moa":"5-HT2B receptor","graph1":"Immunology","graph2":"Phase I","graph3":"AnaMar","amount2":0,"highestDevelopmentShortName":"Ph I","therapeuticAreaShortName":"Immunology","amount2New":0,"dosageForm":"Oral Capsule","sponsorNew":"AnaMar \/ Inapplicable","highestDevelopmentStatusID":"6","companyTruncated":"AnaMar \/ Inapplicable"},{"orgOrder":0,"company":"Cantargia AB","sponsor":"Inapplicable","pharmaFlowCategory":"DU","therapeuticArea":"Immunology","country":"SWEDEN","productType":"Antibody","year":"2023","type":"Inapplicable","leadProduct":"CAN10","moa":"IL-1\/IL-33\/IL-36 receptor","graph1":"Immunology","graph2":"Phase I","graph3":"Cantargia AB","amount2":0,"highestDevelopmentShortName":"Ph I","therapeuticAreaShortName":"Immunology","amount2New":0,"dosageForm":"Subcutaneous Infusion","sponsorNew":"Cantargia AB \/ Inapplicable","highestDevelopmentStatusID":"6","companyTruncated":"Cantargia AB \/ Inapplicable"},{"orgOrder":0,"company":"Cantargia AB","sponsor":"Inapplicable","pharmaFlowCategory":"DU","therapeuticArea":"Immunology","country":"SWEDEN","productType":"Antibody","year":"2024","type":"Inapplicable","leadProduct":"CAN10","moa":"IL-1\/IL-33\/IL-36 receptor","graph1":"Immunology","graph2":"Phase I","graph3":"Cantargia AB","amount2":0,"highestDevelopmentShortName":"Ph I","therapeuticAreaShortName":"Immunology","amount2New":0,"dosageForm":"Subcutaneous Infusion","sponsorNew":"Cantargia AB \/ Inapplicable","highestDevelopmentStatusID":"6","companyTruncated":"Cantargia AB \/ Inapplicable"},{"orgOrder":0,"company":"Cantargia AB","sponsor":"Inapplicable","pharmaFlowCategory":"DU","therapeuticArea":"Immunology","country":"SWEDEN","productType":"Antibody","year":"2022","type":"Inapplicable","leadProduct":"CAN10","moa":"IL-1\/IL-33\/IL-36 receptor","graph1":"Immunology","graph2":"Phase I","graph3":"Cantargia AB","amount2":0,"highestDevelopmentShortName":"Ph I","therapeuticAreaShortName":"Immunology","amount2New":0,"dosageForm":"Subcutaneous Infusion","sponsorNew":"Cantargia AB \/ Inapplicable","highestDevelopmentStatusID":"6","companyTruncated":"Cantargia AB \/ Inapplicable"},{"orgOrder":0,"company":"Zura Bio","sponsor":"Access Biotechnology","pharmaFlowCategory":"D","therapeuticArea":"Immunology","country":"UNITED KINGDOM","productType":"Antibody","year":"2024","type":"Private Placement","leadProduct":"Tibulizumab","moa":"IL-17 receptor\/BAFF receptor","graph1":"Immunology","graph2":"Phase I","graph3":"Zura Bio","amount2":0,"highestDevelopmentShortName":"Ph 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Injection","sponsorNew":"Prometheus Biosciences \/ Inapplicable","highestDevelopmentStatusID":"6","companyTruncated":"Prometheus Biosciences \/ Inapplicable"},{"orgOrder":0,"company":"Kiniksa Pharmaceuticals","sponsor":"Inapplicable","pharmaFlowCategory":"DU","therapeuticArea":"Immunology","country":"U.S.A","productType":"Antibody","year":"2024","type":"Inapplicable","leadProduct":"Abiprubart","moa":"Undisclosed","graph1":"Immunology","graph2":"Phase I","graph3":"Kiniksa Pharmaceuticals","amount2":0,"highestDevelopmentShortName":"Ph I","therapeuticAreaShortName":"Immunology","amount2New":0,"dosageForm":"Subcutaneous Injection","sponsorNew":"Kiniksa Pharmaceuticals \/ Inapplicable","highestDevelopmentStatusID":"6","companyTruncated":"Kiniksa Pharmaceuticals \/ Inapplicable"},{"orgOrder":0,"company":"Kiniksa 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Sciences"},{"orgOrder":0,"company":"ImmuneSensor Therapeutics","sponsor":"Inapplicable","pharmaFlowCategory":"DU","therapeuticArea":"Immunology","country":"U.S.A","productType":"Other Small Molecule","year":"2024","type":"Inapplicable","leadProduct":"IMSB301","moa":"Undisclosed","graph1":"Immunology","graph2":"Phase I","graph3":"ImmuneSensor Therapeutics","amount2":0,"highestDevelopmentShortName":"Ph I","therapeuticAreaShortName":"Immunology","amount2New":0,"dosageForm":"Undisclosed","sponsorNew":"ImmuneSensor Therapeutics \/ Inapplicable","highestDevelopmentStatusID":"6","companyTruncated":"ImmuneSensor Therapeutics \/ Inapplicable"},{"orgOrder":0,"company":"Seismic Therapeutic","sponsor":"Inapplicable","pharmaFlowCategory":"DU","therapeuticArea":"Immunology","country":"U.S.A","productType":"Antibody","year":"2025","type":"Inapplicable","leadProduct":"S-4321","moa":"PD\u20111\/c\u03b3RIIb","graph1":"Immunology","graph2":"Phase I","graph3":"Seismic Therapeutic","amount2":0,"highestDevelopmentShortName":"Ph I","therapeuticAreaShortName":"Immunology","amount2New":0,"dosageForm":"Subcutaneous Injection","sponsorNew":"Seismic Therapeutic \/ Inapplicable","highestDevelopmentStatusID":"6","companyTruncated":"Seismic Therapeutic \/ Inapplicable"}]

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                            01

                            Dr. Reddy's Laboratories

                            India
                            MAGHREB PHARMA
                            Attending
                            • fda
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                            Virtual BoothDRL offers a portfolio of products & services, including APIs, CMO services, generics, biosimilars & differentiated formulations.

                            Lead Product(s) : Tocilizumab

                            Therapeutic Area : Immunology

                            Study Phase : Phase I

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

                            DEALS_DEV arrow-down

                            Dr. Reddy’s Successfully Completes Phase I Study (IV Route) of DRL_TC, a Proposed Biosimilar of Tocilizumab

                            Details : Tocilizumab Biosimilar is a recombinant humanized monoclonal antibody targeting IL-6R, which specifically binds to sIL-6R and mIL-6R and inhibits signaling mediated by sIL-6R or mIL-6R. It is approved for the treatment of RA, sJIA, and CRS.

                            Product Name : DRL_TC

                            Product Type : Antibody

                            Upfront Cash : Inapplicable

                            May 06, 2023

                            Lead Product(s) : Tocilizumab

                            Therapeutic Area : Immunology

                            Highest Development Status : Phase I

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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                            02

                            Dr. Reddy's Laboratories

                            India
                            MAGHREB PHARMA
                            Attending
                            • fda
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                            • WHO-GMP
                            Virtual BoothDRL offers a portfolio of products & services, including APIs, CMO services, generics, biosimilars & differentiated formulations.

                            Lead Product(s) : Tocilizumab

                            Therapeutic Area : Immunology

                            Study Phase : Phase I

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

                            DEALS_DEV arrow-down

                            Dr. Reddy’s Successfully Completes Phase 1 Study Of DRL_TC, a Proposed Biosimilar of Tocilizumab

                            Details : Tocilizumab is an important anti-rheumatic agent used in the treatment of adult patients with moderate to severe active rheumatoid arthritis who have had an inadequate response to one or more Disease-Modifying Anti-Rheumatic Drugs (DMARDs).

                            Product Name : DRL_TC

                            Product Type : Antibody

                            Upfront Cash : Inapplicable

                            December 19, 2022

                            Lead Product(s) : Tocilizumab

                            Therapeutic Area : Immunology

                            Highest Development Status : Phase I

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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                            03

                            Seismic Therapeutic

                            U.S.A arrow
                            German Wound Congress
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                            Seismic Therapeutic

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                            German Wound Congress
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                            • fda
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                            • WHO-GMP
                            Virtual Booth Boost your online visibility by uploading your products, APIs, FDFs, intermediates, excipients, and services for free on PharmaCompass. Rank higher among suppliers and expand your reach across the internet efficiently and cost-effectively.

                            Lead Product(s) : S-4321

                            Therapeutic Area : Immunology

                            Study Phase : Phase I

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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                            Seismic Doses First Patients with S-4321 PD-1/FcγRIIb Autoimmune Drug

                            Details : S-4321 is a novel bifunctional antibody that agonizes PD-1 and FcγRIIb inhibitory receptors for the treatment of autoimmune disease.

                            Product Name : S-4321

                            Product Type : Antibody

                            Upfront Cash : Inapplicable

                            April 10, 2025

                            Lead Product(s) : S-4321

                            Therapeutic Area : Immunology

                            Highest Development Status : Phase I

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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                            04

                            Tr1X Bio

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                            German Wound Congress
                            Not Confirmed

                            Tr1X Bio

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                            German Wound Congress
                            Not Confirmed
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                            Lead Product(s) : TRX103

                            Therapeutic Area : Immunology

                            Study Phase : Phase I

                            Sponsor : California Institute for Regenerative Medicine

                            Deal Size : $8.0 million

                            Deal Type : Funding

                            DEALS_DEV arrow-down

                            Tr1x Awarded $8 Million Cirm Grant for TRX103 Phase 1/2a Clinical Trial

                            Details : The funding aims to advance the development of TRX103 an engineered Tr1 Treg cell therapy for use in the prevention of GvHD in blood cancer patients undergoing mismatched stem cell transplants.

                            Product Name : TRX103

                            Product Type : Cell and Gene therapy

                            Upfront Cash : Undisclosed

                            April 04, 2025

                            Lead Product(s) : TRX103

                            Therapeutic Area : Immunology

                            Highest Development Status : Phase I

                            Sponsor : California Institute for Regenerative Medicine

                            Deal Size : $8.0 million

                            Deal Type : Funding

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                            05

                            Allakos

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                            German Wound Congress
                            Not Confirmed

                            Allakos

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                            German Wound Congress
                            Not Confirmed
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                            Lead Product(s) : AK006

                            Therapeutic Area : Immunology

                            Study Phase : Phase I

                            Sponsor : Concentra Biosciences

                            Deal Size : Undisclosed

                            Deal Type : Acquisition

                            DEALS_DEV arrow-down

                            Allakos to Be Acquired By Concentra Biosciences for $0.33 Per Share

                            Details : Through the acquisition, Company will be developing therapeutics that target immunomodulatory receptors, including AK006, a humanized IgG1 monoclonal antibody.

                            Product Name : AK006

                            Product Type : Antibody

                            Upfront Cash : Undisclosed

                            April 02, 2025

                            Lead Product(s) : AK006

                            Therapeutic Area : Immunology

                            Highest Development Status : Phase I

                            Sponsor : Concentra Biosciences

                            Deal Size : Undisclosed

                            Deal Type : Acquisition

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                            06

                            Dren Bio

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                            German Wound Congress
                            Not Confirmed

                            Dren Bio

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                            German Wound Congress
                            Not Confirmed
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                            Lead Product(s) : DR-0201

                            Therapeutic Area : Immunology

                            Study Phase : Phase I

                            Sponsor : Sanofi

                            Deal Size : $1,900.0 million

                            Deal Type : Acquisition

                            DEALS_DEV arrow-down

                            Sanofi to Acquire Dren Bio's Immunology Unit

                            Details : Sanofi acquires DR-0201 from Dren. It is CD20-directed bispecific antibody that targets & engages specific tissue-resident & trafficking myeloid cells to induce deep B-cell depletion.

                            Product Name : DR-0201

                            Product Type : Antibody

                            Upfront Cash : $600.0 million

                            March 20, 2025

                            Lead Product(s) : DR-0201

                            Therapeutic Area : Immunology

                            Highest Development Status : Phase I

                            Sponsor : Sanofi

                            Deal Size : $1,900.0 million

                            Deal Type : Acquisition

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                            07

                            Seismic Therapeutic

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                            German Wound Congress
                            Not Confirmed

                            Seismic Therapeutic

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                            German Wound Congress
                            Not Confirmed
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                            Lead Product(s) : S‑1117

                            Therapeutic Area : Immunology

                            Study Phase : Phase I

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

                            DEALS_DEV arrow-down

                            Seismic Doses First Cohort in Phase 1 Trial of S-1117 for Antibody Diseases

                            Details : S‑1117 is a novel engineered Fc-fused pan-immunoglobin G (IgG) protease targeting IgG autoantibodies, which is being evaluated for the treatment of autoimmune diseases.

                            Product Name : S‑1117

                            Product Type : Enzyme

                            Upfront Cash : Inapplicable

                            March 11, 2025

                            Lead Product(s) : S‑1117

                            Therapeutic Area : Immunology

                            Highest Development Status : Phase I

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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                            08

                            NovelMed Therapeutics

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                            German Wound Congress
                            Not Confirmed

                            NovelMed Therapeutics

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                            German Wound Congress
                            Not Confirmed
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                            Lead Product(s) : Ruxoprubart

                            Therapeutic Area : Immunology

                            Study Phase : Phase I

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

                            DEALS_DEV arrow-down

                            FDA Approves NM8074 (ruxoprubart) IND for Dermatomyositis (DM)

                            Details : NM8074 (ruxoprubart) is an alternative pathway (AP) blocker anti-Bb antibody. It is being evaluated for the treatment of dermatomyositis .

                            Product Name : NM8074

                            Product Type : Antibody

                            Upfront Cash : Inapplicable

                            February 24, 2025

                            Lead Product(s) : Ruxoprubart

                            Therapeutic Area : Immunology

                            Highest Development Status : Phase I

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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                            09

                            Ensho Therapeutics

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                            German Wound Congress
                            Not Confirmed

                            Ensho Therapeutics

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                            German Wound Congress
                            Not Confirmed
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                            Lead Product(s) : NSHO-101

                            Therapeutic Area : Immunology

                            Study Phase : Phase I

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

                            DEALS_DEV arrow-down

                            Ensho to Present NSHO-101 Phase 1 Data for IBD at ECCO 2025

                            Details : EA1080 (NSHO-101) is an oral α4β7 integrin antagonist, small molecule drug candidate, which is being evaluated for the treatment of inflammatory bowel disease.

                            Product Name : EA1080

                            Product Type : Other Small Molecule

                            Upfront Cash : Inapplicable

                            February 14, 2025

                            Lead Product(s) : NSHO-101

                            Therapeutic Area : Immunology

                            Highest Development Status : Phase I

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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                            10

                            MaxCyte

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                            German Wound Congress
                            Not Confirmed

                            MaxCyte

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                            German Wound Congress
                            Not Confirmed
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                            Lead Product(s) : Azercabtagene Zapreleucel

                            Therapeutic Area : Immunology

                            Study Phase : Phase I

                            Sponsor : TG Therapeutics

                            Deal Size : Undisclosed

                            Deal Type : Licensing Agreement

                            DEALS_DEV arrow-down

                            MaxCyte Signs License With TG Therapeutics for Autoimmune Cell Therapy

                            Details : Under the licensing agreement, TG Therapeutics obtains commercial rights to use MaxCyte’s Flow Electroporation® technology and ExPERT™ platform.

                            Product Name : Azer-cel

                            Product Type : Cell and Gene therapy

                            Upfront Cash : Undisclosed

                            February 12, 2025

                            Lead Product(s) : Azercabtagene Zapreleucel

                            Therapeutic Area : Immunology

                            Highest Development Status : Phase I

                            Sponsor : TG Therapeutics

                            Deal Size : Undisclosed

                            Deal Type : Licensing Agreement

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