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Find Novel Immunology Drugs in Preclinical Development
miCAR19, is an anti-CD19 CAR T-cell &gene therapy candidate, which is currently being evaluated for the treatment of B-cell driven autoimmune diseases.
Through the license agreement, Nektar will utilize the Biolojic Design program TNFR2 receptor agonist, currently undergoing early-stage clinical trials for treating autoimmune diseases.
Under the collaboration, Sanofi will create and develop IgM agonist antibodies will now focus exclusively on immunology/inflammation targets by leveraging proprietary IgM antibody technology platform.
Under the licensing agreement, AbbVie to develop OSE-230, a monoclonal antibody designed to resolve chronic and severe inflammation, currently in the pre-clinical development stage.
Under the terms of the agreement, Kumquat granted Takeda an exclusive, global, and royalty bearing license to develop and commercialize a novel immuno-oncology small molecule inhibitor as a mono- and/or combination-therapy.
Century intends to use the net proceeds to support the expansion of CNTY-101, a CD19-targeting iNK cell therapy, currently being evaluated in a clinical trial in B-cell malignancies.
The collaboration aims to support the clinical development of GS-6791 (NX-0479), a potent, selective, oral IRAK4 degrader that has potential applications in the treatment of rheumatoid arthritis and other inflammatory diseases
The proceeds will be used to advance CPTX2309, Capstan’s lead in vivo chimeric antigen receptor T cell (CAR-T) candidate, to early clinical proof-of-concept in autoimmune disorders, and to further develop Capstan’s tLNP pipeline.
The acquisition provides Novartis with full rights to IFM Due's portfolio of STING antagonists, which have the potential to treat an array of serious inflammation-driven diseases characterized by excessive interferon and other pro-inflammatory cytokine signaling.