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Inapplicable"},{"orgOrder":0,"company":"3PBiovian","sponsor":"Toleranzia","pharmaFlowCategory":"D","therapeuticArea":"Immunology","country":"SPAIN","productType":"Protein","year":"2020","type":"Partnership","leadProduct":"TOL2","moa":"Undisclosed","graph1":"Immunology","graph2":"Preclinical","graph3":"3PBiovian","amount2":0,"highestDevelopmentShortName":"Preclinical","therapeuticAreaShortName":"Immunology","amount2New":0,"dosageForm":"Undisclosed","sponsorNew":"3PBiovian \/ Toleranzia","highestDevelopmentStatusID":"4","companyTruncated":"3PBiovian \/ Toleranzia"},{"orgOrder":0,"company":"Aditxt","sponsor":"H.C. Wainwright & Co","pharmaFlowCategory":"D","therapeuticArea":"Immunology","country":"U.S.A","productType":"Oligonucleotide","year":"2022","type":"Public Offering","leadProduct":"Undisclosed","moa":"Undisclosed","graph1":"Immunology","graph2":"Preclinical","graph3":"Aditxt","amount2":0,"highestDevelopmentShortName":"Preclinical","therapeuticAreaShortName":"Immunology","amount2New":0,"dosageForm":"Subcutaneous Injection","sponsorNew":"Aditxt \/ H.C. Wainwright & Co","highestDevelopmentStatusID":"4","companyTruncated":"Aditxt \/ H.C. Wainwright & Co"},{"orgOrder":0,"company":"IgGenix","sponsor":"Alexandria Venture","pharmaFlowCategory":"D","therapeuticArea":"Immunology","country":"U.S.A","productType":"Undisclosed","year":"2023","type":"Series B Financing","leadProduct":"Undisclosed","moa":"Undisclosed","graph1":"Immunology","graph2":"Preclinical","graph3":"IgGenix","amount2":0,"highestDevelopmentShortName":"Preclinical","therapeuticAreaShortName":"Immunology","amount2New":0,"dosageForm":"Oral","sponsorNew":"IgGenix \/ Alexandria Venture","highestDevelopmentStatusID":"4","companyTruncated":"IgGenix \/ Alexandria Venture"},{"orgOrder":0,"company":"Medicinova","sponsor":"Inapplicable","pharmaFlowCategory":"DU","therapeuticArea":"Immunology","country":"U.S.A","productType":"Other Small Molecule","year":"2023","type":"Inapplicable","leadProduct":"Tipelukast","moa":"5-LOX","graph1":"Immunology","graph2":"Preclinical","graph3":"Medicinova","amount2":0,"highestDevelopmentShortName":"Preclinical","therapeuticAreaShortName":"Immunology","amount2New":0,"dosageForm":"Oral Tablet","sponsorNew":"Medicinova \/ Inapplicable","highestDevelopmentStatusID":"4","companyTruncated":"Medicinova \/ Inapplicable"},{"orgOrder":0,"company":"BioInvent","sponsor":"Cantargia AB","pharmaFlowCategory":"D","therapeuticArea":"Immunology","country":"SWEDEN","productType":"Antibody","year":"2020","type":"Agreement","leadProduct":"CAN10","moa":"IL-1\/IL-33\/IL-36 receptor","graph1":"Immunology","graph2":"Preclinical","graph3":"BioInvent","amount2":0,"highestDevelopmentShortName":"Preclinical","therapeuticAreaShortName":"Immunology","amount2New":0,"dosageForm":"Subcutaneous Infusion","sponsorNew":"BioInvent \/ Cantargia AB","highestDevelopmentStatusID":"4","companyTruncated":"BioInvent \/ Cantargia AB"},{"orgOrder":0,"company":"Corvus Pharmaceuticals","sponsor":"Inapplicable","pharmaFlowCategory":"DU","therapeuticArea":"Immunology","country":"U.S.A","productType":"Other Small Molecule","year":"2024","type":"Inapplicable","leadProduct":"Soquelitinib","moa":"ITK","graph1":"Immunology","graph2":"Preclinical","graph3":"Corvus Pharmaceuticals","amount2":0,"highestDevelopmentShortName":"Preclinical","therapeuticAreaShortName":"Immunology","amount2New":0,"dosageForm":"Undisclosed","sponsorNew":"Corvus Pharmaceuticals \/ Inapplicable","highestDevelopmentStatusID":"4","companyTruncated":"Corvus Pharmaceuticals \/ Inapplicable"},{"orgOrder":0,"company":"Theraly Fibrosis","sponsor":"Inapplicable","pharmaFlowCategory":"DU","therapeuticArea":"Immunology","country":"U.S.A","productType":"Protein","year":"2020","type":"Inapplicable","leadProduct":"TLY012","moa":"DR5","graph1":"Immunology","graph2":"Preclinical","graph3":"Theraly Fibrosis","amount2":0,"highestDevelopmentShortName":"Preclinical","therapeuticAreaShortName":"Immunology","amount2New":0,"dosageForm":"Undisclosed","sponsorNew":"Theraly Fibrosis \/ Inapplicable","highestDevelopmentStatusID":"4","companyTruncated":"Theraly Fibrosis \/ Inapplicable"},{"orgOrder":0,"company":"EydisBio","sponsor":"Inapplicable","pharmaFlowCategory":"DU","therapeuticArea":"Immunology","country":"U.S.A","productType":"Other Small Molecule","year":"2024","type":"Inapplicable","leadProduct":"EYD-001","moa":"Undisclosed","graph1":"Immunology","graph2":"Preclinical","graph3":"EydisBio","amount2":0,"highestDevelopmentShortName":"Preclinical","therapeuticAreaShortName":"Immunology","amount2New":0,"dosageForm":"Undisclosed","sponsorNew":"EydisBio \/ Inapplicable","highestDevelopmentStatusID":"4","companyTruncated":"EydisBio \/ Inapplicable"},{"orgOrder":0,"company":"EydisBio","sponsor":"National Institutes of Health","pharmaFlowCategory":"D","therapeuticArea":"Immunology","country":"U.S.A","productType":"Other Small Molecule","year":"2024","type":"Funding","leadProduct":"EYD-001","moa":"Undisclosed","graph1":"Immunology","graph2":"Preclinical","graph3":"EydisBio","amount2":0,"highestDevelopmentShortName":"Preclinical","therapeuticAreaShortName":"Immunology","amount2New":0,"dosageForm":"Undisclosed","sponsorNew":"EydisBio \/ National Institutes of Health","highestDevelopmentStatusID":"4","companyTruncated":"EydisBio \/ National Institutes of Health"},{"orgOrder":0,"company":"BITT","sponsor":"National Institutes of Health","pharmaFlowCategory":"D","therapeuticArea":"Immunology","country":"U.S.A","productType":"Other Large Molecule","year":"2023","type":"Funding","leadProduct":"BITT-101","moa":"CD40","graph1":"Immunology","graph2":"Preclinical","graph3":"BITT","amount2":0,"highestDevelopmentShortName":"Preclinical","therapeuticAreaShortName":"Immunology","amount2New":0,"dosageForm":"Undisclosed","sponsorNew":"BITT \/ National Institutes of Health","highestDevelopmentStatusID":"4","companyTruncated":"BITT \/ National Institutes of Health"},{"orgOrder":0,"company":"ImmunOs Therapeutics","sponsor":"Eurostars","pharmaFlowCategory":"D","therapeuticArea":"Immunology","country":"SWITZERLAND","productType":"Other Large Molecule","year":"2021","type":"Funding","leadProduct":"OCi mAb","moa":"Undisclosed","graph1":"Immunology","graph2":"Preclinical","graph3":"ImmunOs Therapeutics","amount2":0,"highestDevelopmentShortName":"Preclinical","therapeuticAreaShortName":"Immunology","amount2New":0,"dosageForm":"Undisclosed","sponsorNew":"ImmunOs Therapeutics \/ Eurostars","highestDevelopmentStatusID":"4","companyTruncated":"ImmunOs Therapeutics \/ Eurostars"},{"orgOrder":0,"company":"Massachusetts General Hospital","sponsor":"Theriva Biologics","pharmaFlowCategory":"D","therapeuticArea":"Immunology","country":"U.S.A","productType":"Enzyme","year":"2020","type":"Licensing Agreement","leadProduct":"SYN-020","moa":"Intestinal alkaline phosphatase","graph1":"Immunology","graph2":"Preclinical","graph3":"Massachusetts General Hospital","amount2":0,"highestDevelopmentShortName":"Preclinical","therapeuticAreaShortName":"Immunology","amount2New":0,"dosageForm":"Oral","sponsorNew":"Massachusetts General Hospital \/ Theriva Biologics","highestDevelopmentStatusID":"4","companyTruncated":"Massachusetts General Hospital \/ Theriva Biologics"},{"orgOrder":0,"company":"Artax Biopharma","sponsor":"Inapplicable","pharmaFlowCategory":"DU","therapeuticArea":"Immunology","country":"U.S.A","productType":"Other Small Molecule","year":"2021","type":"Inapplicable","leadProduct":"AX-158","moa":"Nck-SH3.1 domain","graph1":"Immunology","graph2":"Preclinical","graph3":"Artax Biopharma","amount2":0,"highestDevelopmentShortName":"Preclinical","therapeuticAreaShortName":"Immunology","amount2New":0,"dosageForm":"Oral","sponsorNew":"Artax Biopharma \/ Inapplicable","highestDevelopmentStatusID":"4","companyTruncated":"Artax Biopharma \/ Inapplicable"},{"orgOrder":0,"company":"Thymmune Therapeutics","sponsor":"Pillar VC","pharmaFlowCategory":"D","therapeuticArea":"Immunology","country":"U.S.A","productType":"Cell and Gene therapy","year":"2023","type":"Financing","leadProduct":"THY-100","moa":"Undisclosed","graph1":"Immunology","graph2":"Preclinical","graph3":"Thymmune Therapeutics","amount2":0,"highestDevelopmentShortName":"Preclinical","therapeuticAreaShortName":"Immunology","amount2New":0,"dosageForm":"Undisclosed","sponsorNew":"Thymmune Therapeutics \/ Pillar VC","highestDevelopmentStatusID":"4","companyTruncated":"Thymmune Therapeutics \/ Pillar VC"}]

    Find Novel Immunology Drugs in Preclinical Development

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                            01

                            RayThera

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                            German Wound Congress
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                            RayThera

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                            German Wound Congress
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                            Lead Product(s) : Undisclosed

                            Therapeutic Area : Immunology

                            Study Phase : Preclinical

                            Sponsor : Foresite Capital

                            Deal Size : $110.0 million

                            Deal Type : Series A Financing

                            DEALS_DEV arrow-down

                            RayThera Raises $110 Million in Series A Financing

                            Details : The proceeds from the financing will be used to advance RayThera’s lead drug candidates through Phase 1 clinical studies.

                            Product Name : Undisclosed

                            Product Type : Other Small Molecule

                            Upfront Cash : Undisclosed

                            April 04, 2025

                            Lead Product(s) : Undisclosed

                            Therapeutic Area : Immunology

                            Highest Development Status : Preclinical

                            Sponsor : Foresite Capital

                            Deal Size : $110.0 million

                            Deal Type : Series A Financing

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                            02

                            PinCell

                            Italy arrow
                            German Wound Congress
                            Not Confirmed

                            PinCell

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                            German Wound Congress
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                            Lead Product(s) : PC111

                            Therapeutic Area : Immunology

                            Study Phase : Preclinical

                            Sponsor : Scinai Immunotherapeutics

                            Deal Size : Undisclosed

                            Deal Type : Agreement

                            DEALS_DEV arrow-down

                            Scinai Signs an Option Agreement to Acquire Rare Disease Company Pincell

                            Details : The agreement aims for the acquisition of Pincell and its monoclonal antibody, PC111, that binds to the human soluble Fas ligand and thus blocks its activation of apoptosis of skin cells.

                            Product Name : PC111

                            Product Type : Antibody

                            Upfront Cash : Undisclosed

                            March 27, 2025

                            Lead Product(s) : PC111

                            Therapeutic Area : Immunology

                            Highest Development Status : Preclinical

                            Sponsor : Scinai Immunotherapeutics

                            Deal Size : Undisclosed

                            Deal Type : Agreement

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                            03

                            Belhaven Biopharma

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                            German Wound Congress
                            Not Confirmed

                            Belhaven Biopharma

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                            German Wound Congress
                            Not Confirmed
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                            Lead Product(s) : Epinephrine

                            Therapeutic Area : Immunology

                            Study Phase : Preclinical

                            Sponsor : Undisclosed

                            Deal Size : $11.0 million

                            Deal Type : Financing

                            DEALS_DEV arrow-down

                            Belhaven Raises $11M for Nasdepi(R), Nasal Breakthrough for Anaphylaxis

                            Details : The financing from the proceeds will support the development of Nasdepi (epinephrine). It is being evaluated for the treatment of Anaphylactic reactions due to severe allergies.

                            Product Name : Nasdepi

                            Product Type : Hormone

                            Upfront Cash : Undisclosed

                            January 22, 2025

                            Lead Product(s) : Epinephrine

                            Therapeutic Area : Immunology

                            Highest Development Status : Preclinical

                            Sponsor : Undisclosed

                            Deal Size : $11.0 million

                            Deal Type : Financing

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                            04

                            Hinge Bio

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                            German Wound Congress
                            Not Confirmed

                            Hinge Bio

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                            German Wound Congress
                            Not Confirmed
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                            Lead Product(s) : HB2198

                            Therapeutic Area : Immunology

                            Study Phase : Preclinical

                            Sponsor : Ridgeback Capital

                            Deal Size : $30.0 million

                            Deal Type : Series A Financing

                            DEALS_DEV arrow-down

                            Hinge Bio Secures $30M Series A’ for GEM-DIMER Platform Therapies

                            Details : The proceeds will support the Company in advancing its lead product candidate, HB2198, into a clinical trial in patients living with Systemic Lupus Erythematosus.

                            Product Name : HB2198

                            Product Type : Antibody

                            Upfront Cash : Undisclosed

                            January 15, 2025

                            Lead Product(s) : HB2198

                            Therapeutic Area : Immunology

                            Highest Development Status : Preclinical

                            Sponsor : Ridgeback Capital

                            Deal Size : $30.0 million

                            Deal Type : Series A Financing

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                            05

                            Leo Pharma

                            Denmark arrow
                            German Wound Congress
                            Not Confirmed

                            Leo Pharma

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                            German Wound Congress
                            Not Confirmed
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                            Lead Product(s) : Undisclosed

                            Therapeutic Area : Immunology

                            Study Phase : Preclinical

                            Sponsor : Gilead Sciences

                            Deal Size : $1,700.0 million

                            Deal Type : Partnership

                            DEALS_DEV arrow-down

                            Gilead, LEO Pharma Partner to Develop Programs for Inflammatory Diseases

                            Details : The partnership aims to accelerate the development and commercialization of LEO Pharma’s small molecule oral STAT6 programs for the potential treatment of patients with inflammatory diseases.

                            Product Name : Undisclosed

                            Product Type : Other Small Molecule

                            Upfront Cash : $250.0 million

                            January 11, 2025

                            Lead Product(s) : Undisclosed

                            Therapeutic Area : Immunology

                            Highest Development Status : Preclinical

                            Sponsor : Gilead Sciences

                            Deal Size : $1,700.0 million

                            Deal Type : Partnership

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                            06

                            Nudge Therapeutics

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                            German Wound Congress
                            Not Confirmed

                            Nudge Therapeutics

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                            German Wound Congress
                            Not Confirmed
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                            Lead Product(s) : Undisclosed

                            Therapeutic Area : Immunology

                            Study Phase : Preclinical

                            Sponsor : Veralox Therapeutics

                            Deal Size : Undisclosed

                            Deal Type : Acquisition

                            DEALS_DEV arrow-down

                            Veralox Expands Pipeline with Exclusive Option to Acquire Nudge Therapeutics

                            Details : Through the acquisition, Veralox expands its pipeline by including preclinical cyclic AMP-GMP (cGAS) inhibitor compounds.

                            Product Name : Undisclosed

                            Product Type : Other Small Molecule

                            Upfront Cash : Undisclosed

                            January 09, 2025

                            Lead Product(s) : Undisclosed

                            Therapeutic Area : Immunology

                            Highest Development Status : Preclinical

                            Sponsor : Veralox Therapeutics

                            Deal Size : Undisclosed

                            Deal Type : Acquisition

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                            07

                            Cyrus Biotechnology

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                            German Wound Congress
                            Not Confirmed

                            Cyrus Biotechnology

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                            German Wound Congress
                            Not Confirmed
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                            Lead Product(s) : CYR212

                            Therapeutic Area : Immunology

                            Study Phase : Preclinical

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

                            DEALS_DEV arrow-down

                            Cyrus Biotechnology Selects CYR212 for Chronic Autoimmune Disease Treatment

                            Details : CYR212 to deplete circulating IgG, it has the potential to be the first approved IgG-lowering agent in myasthenia gravis and immune thrombocytopenia.

                            Product Name : CYR212

                            Product Type : Cell and Gene therapy

                            Upfront Cash : Inapplicable

                            January 09, 2025

                            Lead Product(s) : CYR212

                            Therapeutic Area : Immunology

                            Highest Development Status : Preclinical

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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                            08

                            WuXi Biologics

                            China arrow
                            German Wound Congress
                            Not Confirmed

                            WuXi Biologics

                            China arrow
                            German Wound Congress
                            Not Confirmed
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                            Lead Product(s) : Undisclosed

                            Therapeutic Area : Immunology

                            Study Phase : Preclinical

                            Sponsor : Candid Therapeutics

                            Deal Size : $925.0 million

                            Deal Type : Agreement

                            DEALS_DEV arrow-down

                            Candid Steps up TCE Deal Momentum with $925M WuXi Partnership

                            Details : Under the agreement, Candid will have exclusive global rights to a tri-specific T-cell Engager discovered by the WuXi Biologics platform for treating autoimmune and inflammatory diseases.

                            Product Name : Undisclosed

                            Product Type : Antibody

                            Upfront Cash : Undisclosed

                            January 06, 2025

                            Lead Product(s) : Undisclosed

                            Therapeutic Area : Immunology

                            Highest Development Status : Preclinical

                            Sponsor : Candid Therapeutics

                            Deal Size : $925.0 million

                            Deal Type : Agreement

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                            09

                            Generation Bio

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                            German Wound Congress
                            Not Confirmed

                            Generation Bio

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                            German Wound Congress
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                            Lead Product(s) : Undisclosed

                            Therapeutic Area : Immunology

                            Study Phase : Preclinical

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

                            DEALS_DEV arrow-down

                            Generation Bio Applies ctLNP Technology to Develop siRNA Therapies for Autoimmune

                            Details : siRNA based therapies works by silencing disease-driving targets in T cells, these are being developed for the treatment of autoimmune diseases.

                            Product Name : Undisclosed

                            Product Type : Oligonucleotide

                            Upfront Cash : Inapplicable

                            January 06, 2025

                            Lead Product(s) : Undisclosed

                            Therapeutic Area : Immunology

                            Highest Development Status : Preclinical

                            Sponsor : Inapplicable

                            Deal Size : Inapplicable

                            Deal Type : Inapplicable

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                            10

                            Orphagen Pharmaceuticals

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                            German Wound Congress
                            Not Confirmed

                            Orphagen Pharmaceuticals

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                            German Wound Congress
                            Not Confirmed
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                            Lead Product(s) : OR-812

                            Therapeutic Area : Immunology

                            Study Phase : Preclinical

                            Sponsor : NIDDK

                            Deal Size : $1.7 million

                            Deal Type : Funding

                            DEALS_DEV arrow-down

                            Orphagen Receives NIH Funding to Advance Inflammatory Bowel Disease Drug

                            Details : The funding will support the development of the small molecule OR-812, a selective nuclear receptor antagonist, as a novel oral therapeutic for treatment of ulcerative colitis and Crohn’s disease

                            Product Name : OR-812

                            Product Type : Other Small Molecule

                            Upfront Cash : Undisclosed

                            December 09, 2024

                            Lead Product(s) : OR-812

                            Therapeutic Area : Immunology

                            Highest Development Status : Preclinical

                            Sponsor : NIDDK

                            Deal Size : $1.7 million

                            Deal Type : Funding

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